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Single Channel

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Single Channel Model

Description | Equations | Implementation | Examples | Discussion

Discussion

This is a simulation for a single channel kinetics in stochastic terms. The basic kinetic model for a single channel is
                                                  C = = O
where C represents the closed state, and O represents the open state of the membrane protein. Let's assume that the rate constants for the two steps are k1 and k_1. 

For a single channel, it opens and closes successively in a stochastic term. The distribution for the open state (and closed state) is an exponential function with the mean dwell-time inversely proportional the rate constant. 

Now if there are two channels, then conductance can be either 0, or 1, or 2. 

When there are 1000 independent, identical channels are present, the behavior is essentially deterministic. The "macroscopic" behavior can be predicated by the law of mass action.