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APPENDIX B. PLOTS FROM SELECTED TUTORIAL EXERCISES

This appendix shows the plots that should be produced by several of the tutorial exercises. The plots shown here will not be identical to those produced on- line; the model and data curve symbols will differ, and additional labels and annotation have been added. The magnitudes and shapes of the simulation output and data curves should, however, be the same as in the tutorial graphs.

Exercise: Input functions (Parameter file 1input.par)

Default parameters: Lagged normal density function:

Exercise: MMID4 configuration (Parameter file 2config.par)

Default parameters:

Exercise: Plotting results (Parameter file 3plots.par)

Default parameters: Permeant outflow, vascular residue, and permeant residue added:

Exercise: Crone calculation of PS (Parameter file 6ps_crone.par)

Default parameters:

Exercise: Influence of PS on exchange (Parameter file 7ps_exch.par)

Default parameters: Experiment PS-1:
Experiment PS-2: Experiment PS-3:

Exercise: Influence of the parenchymal cell (Parameter file 8p_vs_e.par)

Experiment PC-1: Experiment PS-2:

Exercise: Influence of the endothelial cell (Parameter file 9endoth.par)

Experiment EC-1: Experiment EC-3:

Exercise: Choosing an input function (Parameter file 10expinput.par)

LAGNDC input: Constant infusion:
LAGNDC input: Constant infusion:

Exercise: Effect of tracer consumption (Parameter file 11consump.par)

Experiment G-2: Experiment G-3:

Exercise: Heterogeneity of flow (Parameter file 12hetero.par)

Experiment H-1 (Vascular outflow): Experiment H-1 (Permeant outflow, PSpc = 0.1):

Exercise: Manual parameter optimization (Parameter file 14manopt.par)

Initial values: Final fits:

Exercise: Deconvolution (Parameter file 16decon1.par)

Deconvolution results:

Exercise: Deconvolution with nonexchanging vessels (Parameter file 17decon2.par)

Deconvolution results:

Exercise: Parameter optimization with noisy data (Parameter file 18noisopt.par)

Note: The inset graphs shown below show the fit at the peak on a linear scale. These insets are not present on the tutorial output.

Optimization results (10% noise): Optimization results (40% noise):

Exercise: Deconvolution with noisy data (Parameter file 19noisdec.par)

Deconvolution results (10% noise, smoothing=30): Deconvolution results (40% noise, smoothing=100):



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Copyright © 1998, National Simulation Resource, University of Washington.
Last modified 03:47pm PST, March 03, 1998.