APPENDIX B.    Plots from Selected Tutorial Exercises

This appendix shows the plots that should be produced by several of the tutorial exercises. The plots shown here will not be identical to those produced on-line; the model and data curve symbols will differ, and additional labels and annotation have been added. The magnitudes and shapes of the simulation output and data curves should, however, be the same as in the tutorial graphs.

Exercise:    Input functions (Parameter file 1input.par)

Default parameters:
Extracted pic [1]

Lagged normal density function:
Extracted pic [2]

Exercise:    GENTEX configuration (Parameter file 2config.par)

Default parameters:
Extracted pic [3]

Exercise:    Plotting results (Parameter file 3plots.par)

Default parameters:


Extracted pic [4]

Permeant outflow, vascular residue, and permeant residue added:
Extracted pic [5]

Exercise:    Crone calculation of PS (Parameter file 6ps_crone.par)

Default parameters:
Extracted pic [6]

Exercise:    Influence of PS on exchange (Parameter file 7ps_exch.par)

Default parameters:
Extracted pic [7]

Experiment PS-1:
Extracted pic [8]


Experiment PS-2:
Extracted pic [9]


Experiment PS-3:
Extracted pic [10]

Exercise:    Influence of the parenchymal cell (Parameter file 8p_vs_e.par)

Experiment PC-1:
Extracted pic [11]

Experiment PS-2:
Extracted pic [12]

Exercise:    Influence of the endothelial cell (Parameter file 9endoth.par)

Experiment EC-1:
Extracted pic [13]

Experiment EC-3:
Extracted pic [14]

Exercise:    Choosing an input function (Parameter file 10expinput.par)

LAGNDC input:
Extracted pic [15]

Constant infusion:
Extracted pic [16]


LAGNDC input:
Extracted pic [17]


Constant infusion:
Extracted pic [18]

Exercise:    Effect of tracer consumption (Parameter file 11consump.par)

Experiment G-2:
Extracted pic [19]

Experiment G-3:
Extracted pic [20]

Exercise:    Heterogeneity of flow (Parameter file 12hetero.par)

Experiment H-1 (Vascular outflow):
Extracted pic [21]

Experiment H-1 (Permeant outflow, PSpc = 0.1):
Extracted pic [22]

Exercise:    Manual parameter optimization (Parameter file 14manopt.par)

Initial values:
Extracted pic [23]

Final fits:
Extracted pic [24]

Exercise:    Deconvolution (Parameter file 16decon1.par)

Deconvolution results:
Extracted pic [25]

Exercise:    Deconvolution with nonexchanging vessels (Parameter file 17decon2.par)

Deconvolution results:
Extracted pic [26]

Exercise:    Parameter optimization with noisy data (Parameter file 18noisopt.par)

Note: The inset graphs shown below show the fit at the peak on a linear scale. These insets are not present on the tutorial output.

Optimization results (10% noise):
Extracted pic [27]

Optimization results (40% noise):
Extracted pic [28]

Exercise:    Deconvolution with noisy data (Parameter file 19noisdec.par)

Deconvolution results (10% noise, smoothing=30):
Extracted pic [29]

Deconvolution results (40% noise, smoothing=100)
Extracted pic [30]

Copyright 1998-2000, National Simulation Resource, University of Washington, Author: Zheng Li and Rick King <zhengli@bioeng.washington.edu> Last modified: 26 Nov 2000

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