// This model generated automatically from SBML

// unit definitions
import nsrunit;
unit conversion off;

// SBML property definitions
property sbmlRole=string;
property sbmlName=string;
property sbmlCompartment=string;

// SBML reactions
// reaction_0000001: <=> species_0000004 
// reaction_0000002: <=> species_0000007 
// reaction_0000003: <=> species_0000009 
// reaction_0000004: <=> species_0000008 
// reaction_0000005: species_0000008 
// reaction_0000006: species_0000009 
// reaction_0000007: species_0000007 
// reaction_0000008: species_0000004 <=> species_0000005 
// reaction_0000009: species_0000005 <=> species_0000006 
// reaction_0000010: species_0000006 <=> species_0000001 
// reaction_0000011: species_0000001 <=> species_0000002 
// reaction_0000012: species_0000002 <=> species_0000003 
// reaction_0000013: species_0000003 
// reaction_0000014: species_0000008 
// reaction_0000015: species_0000009 
// reaction_0000016: species_0000007 
// reaction_0000017: species_0000004 
// reaction_0000018: species_0000005 
// reaction_0000019: species_0000006 
// reaction_0000020: species_0000001 
// reaction_0000021: species_0000002 
// reaction_0000022: species_0000003 

math main {
  realDomain time second;
  time.min=0;
  extern time.max;
  extern time.delta;

  // variable definitions
  real compartment_0000002 = 1 L;
  real compartment_0000001 = 1 L;
  extern real parameter_0000001_init;
  real parameter_0000001(time);
  extern real parameter_0000002_init;
  real parameter_0000002(time);
  extern real parameter_0000003_init;
  real parameter_0000003(time);
  real parameter_0000005 = .2;
  real parameter_0000006 = .24;
  real parameter_0000007 = .1;
  real parameter_0000008 = .54;
  real parameter_0000010 = .54;
  real parameter_0000011 = .083;
  real parameter_0000012 = .134;
  real parameter_0000013 = .248;
  real parameter_0000014 = .2124;
  real parameter_0000015 = .2124;
  real parameter_0000016 = .2124;
  real parameter_0000017 = 1.062;
  real parameter_0000018 = 1.062;
  real parameter_0000019 = 1.062;
  extern real parameter_0000020_init;
  real parameter_0000020(time);
  extern real parameter_0000021_init;
  real parameter_0000021(time);
  extern real parameter_0000022_init;
  real parameter_0000022(time);
  real parameter_0000023 = 2.8249;
  real parameter_0000024 = 2.8249;
  real parameter_0000025 = 2.8249;
  real parameter_0000026 = 5;
  real parameter_0000027 = 10.62;
  real parameter_0000028 = 76.464;
  real parameter_0000029 = 344.09;
  real parameter_0000030 = 1.062;
  real parameter_0000031 = .02124;
  real parameter_0000032 = .19116;
  real parameter_0000033 = .001062;
  real parameter_0000034 = .38232;
  real parameter_0000036 = .2124;
  real parameter_0000037 = .7434;
  real parameter_0000038 = .6903;
  real parameter_0000039 = 2.8249;
  real parameter_0000040 = 1.6992;
  real parameter_0000041 = .25;
  real parameter_0000042 = .3186;
  real parameter_0000043 = .001;
  real parameter_0000044 = 1.6992;
  real parameter_0000045 = .25;
  real parameter_0000046 = 5.31;
  real parameter_0000047 = .01;
  real parameter_0000048 = .00531;
  real species_0000001(time) nM;
  real species_0000002(time) nM;
  real species_0000003(time) nM;
  real species_0000004(time) nM;
  real species_0000005(time) nM;
  real species_0000006(time) nM;
  real species_0000007(time) nM;
  real species_0000008(time) nM;
  real species_0000009(time) nM;
  real reaction_0000001(time) nmol/hr;
  real reaction_0000002(time) nmol/hr;
  real reaction_0000003(time) nmol/hr;
  real delayExpr0(time);
  real reaction_0000004(time) nmol/hr;
  real reaction_0000005(time) nmol/hr;
  real reaction_0000006(time) nmol/hr;
  real reaction_0000007(time) nmol/hr;
  real reaction_0000008(time) nmol/hr;
  real reaction_0000009(time) nmol/hr;
  real reaction_0000010(time) nmol/hr;
  real reaction_0000011(time) nmol/hr;
  real reaction_0000012(time) nmol/hr;
  real reaction_0000013(time) nmol/hr;
  real reaction_0000014(time) nmol/hr;
  real reaction_0000015(time) nmol/hr;
  real reaction_0000016(time) nmol/hr;
  real reaction_0000017(time) nmol/hr;
  real reaction_0000018(time) nmol/hr;
  real reaction_0000019(time) nmol/hr;
  real reaction_0000020(time) nmol/hr;
  real reaction_0000021(time) nmol/hr;
  real reaction_0000022(time) nmol/hr;

  // equations
  when (time=time.min) parameter_0000001 = parameter_0000001_init;
  parameter_0000001:time = parameter_0000017*(species_0000008/(species_0000008+parameter_0000011))*(parameter_0000005/(parameter_0000005+species_0000001+species_0000002+species_0000003))*(1-parameter_0000001)-parameter_0000014*parameter_0000001;
  when (time=time.min) parameter_0000002 = parameter_0000002_init;
  parameter_0000002:time = parameter_0000018*(species_0000008/(species_0000008+parameter_0000012))*(parameter_0000006/(parameter_0000006+species_0000001+species_0000002+species_0000003))*(1-parameter_0000002)-parameter_0000015*parameter_0000002;
  when (time=time.min) parameter_0000003 = parameter_0000003_init;
  parameter_0000003:time = parameter_0000019*(species_0000008/(species_0000008+parameter_0000013))*(parameter_0000007/(parameter_0000007+species_0000001+species_0000002+species_0000003))*(1-parameter_0000003)-parameter_0000016*parameter_0000003;
  when (time=time.min) parameter_0000020 = parameter_0000020_init;
  parameter_0000020:time = (parameter_0000001^parameter_0000026-parameter_0000020)/parameter_0000023;
  when (time=time.min) parameter_0000021 = parameter_0000021_init;
  parameter_0000021:time = (parameter_0000002^parameter_0000026-parameter_0000021)/parameter_0000024;
  when (time=time.min) parameter_0000022 = parameter_0000022_init;
  parameter_0000022:time = (parameter_0000003^parameter_0000026-parameter_0000022)/parameter_0000025;
  when (time=time.min) species_0000001 = .001;
  species_0000001:time = (reaction_0000010 + -1*reaction_0000011 + -1*reaction_0000020)/compartment_0000001;
  when (time=time.min) species_0000002 = .001;
  species_0000002:time = (reaction_0000011 + -1*reaction_0000012 + -1*reaction_0000021)/compartment_0000001;
  when (time=time.min) species_0000003 = .001;
  species_0000003:time = (reaction_0000012 + -1*reaction_0000013 + -1*reaction_0000022)/compartment_0000001;
  when (time=time.min) species_0000004 = .001;
  species_0000004:time = (reaction_0000001 + -1*reaction_0000008 + -1*reaction_0000017)/compartment_0000002;
  when (time=time.min) species_0000005 = .001;
  species_0000005:time = (reaction_0000008 + -1*reaction_0000009 + -1*reaction_0000018)/compartment_0000002;
  when (time=time.min) species_0000006 = .001;
  species_0000006:time = (reaction_0000009 + -1*reaction_0000010 + -1*reaction_0000019)/compartment_0000002;
  when (time=time.min) species_0000007 = .001;
  species_0000007:time = (reaction_0000002 + -1*reaction_0000007 + -1*reaction_0000016)/compartment_0000001;
  when (time=time.min) species_0000008 = .001;
  species_0000008:time = (reaction_0000004 + -1*reaction_0000005 + -1*reaction_0000014)/compartment_0000001;
  when (time=time.min) species_0000009 = .001;
  species_0000009:time = (reaction_0000003 + -1*reaction_0000006 + -1*reaction_0000015)/compartment_0000001;
  reaction_0000001 = compartment_0000002*(parameter_0000027*parameter_0000021+parameter_0000031);
  reaction_0000002 = compartment_0000001*(parameter_0000028*parameter_0000020+parameter_0000032);
  reaction_0000003 = compartment_0000001*delayExpr0(if (time<(time.min+parameter_0000039)) time.min else time-(parameter_0000039));
  delayExpr0 = parameter_0000029*parameter_0000022+parameter_0000034;
  reaction_0000004 = compartment_0000001*(parameter_0000030*(species_0000009^2/(species_0000009^2+parameter_0000010^2))*(parameter_0000008^2/(species_0000007^2+parameter_0000008^2))+parameter_0000033);
  reaction_0000005 = compartment_0000001*parameter_0000036*species_0000008;
  reaction_0000006 = compartment_0000001*parameter_0000038*species_0000009;
  reaction_0000007 = compartment_0000001*parameter_0000037*species_0000007;
  reaction_0000008 = compartment_0000002*(parameter_0000040*species_0000004/(parameter_0000041+species_0000004));
  reaction_0000009 = compartment_0000002*(parameter_0000040*species_0000005/(parameter_0000041+species_0000005));
  reaction_0000010 = compartment_0000002*(parameter_0000044*species_0000006/(parameter_0000045+species_0000006));
  reaction_0000011 = compartment_0000001*(parameter_0000042*species_0000001/(parameter_0000043+species_0000001));
  reaction_0000012 = compartment_0000001*(parameter_0000042*species_0000002/(parameter_0000043+species_0000002));
  reaction_0000013 = compartment_0000001*(parameter_0000046*species_0000003/(parameter_0000047+species_0000003));
  reaction_0000014 = compartment_0000001*parameter_0000048*species_0000008;
  reaction_0000015 = compartment_0000001*parameter_0000048*species_0000009;
  reaction_0000016 = compartment_0000001*parameter_0000048*species_0000007;
  reaction_0000017 = compartment_0000002*parameter_0000048*species_0000004;
  reaction_0000018 = compartment_0000002*parameter_0000048*species_0000005;
  reaction_0000019 = compartment_0000002*parameter_0000048*species_0000006;
  reaction_0000020 = compartment_0000001*parameter_0000048*species_0000001;
  reaction_0000021 = compartment_0000001*parameter_0000048*species_0000002;
  reaction_0000022 = compartment_0000001*parameter_0000048*species_0000003;

  // variable properties
  compartment_0000002.sbmlRole="compartment";
  compartment_0000002.sbmlName="cytoplasm";
  compartment_0000001.sbmlRole="compartment";
  compartment_0000001.sbmlName="nucleus";
  parameter_0000001_init.sbmlRole="derived";
  parameter_0000001.sbmlRole="parameter";
  parameter_0000001.sbmlName="ACvri";
  parameter_0000002_init.sbmlRole="derived";
  parameter_0000002.sbmlRole="parameter";
  parameter_0000002.sbmlName="ACper";
  parameter_0000003_init.sbmlRole="derived";
  parameter_0000003.sbmlRole="parameter";
  parameter_0000003.sbmlName="ACpdp";
  parameter_0000005.sbmlRole="parameter";
  parameter_0000005.sbmlName="Kpv";
  parameter_0000006.sbmlRole="parameter";
  parameter_0000006.sbmlName="Kpp";
  parameter_0000007.sbmlRole="parameter";
  parameter_0000007.sbmlName="Kppd";
  parameter_0000008.sbmlRole="parameter";
  parameter_0000008.sbmlName="Kvc";
  parameter_0000010.sbmlRole="parameter";
  parameter_0000010.sbmlName="Kpdc";
  parameter_0000011.sbmlRole="parameter";
  parameter_0000011.sbmlName="Kcv";
  parameter_0000012.sbmlRole="parameter";
  parameter_0000012.sbmlName="Kcp";
  parameter_0000013.sbmlRole="parameter";
  parameter_0000013.sbmlName="Kcpd";
  parameter_0000014.sbmlRole="parameter";
  parameter_0000014.sbmlName="Kvdeac";
  parameter_0000015.sbmlRole="parameter";
  parameter_0000015.sbmlName="Kpdeac";
  parameter_0000016.sbmlRole="parameter";
  parameter_0000016.sbmlName="Kpddeac";
  parameter_0000017.sbmlRole="parameter";
  parameter_0000017.sbmlName="Fv";
  parameter_0000018.sbmlRole="parameter";
  parameter_0000018.sbmlName="Fp";
  parameter_0000019.sbmlRole="parameter";
  parameter_0000019.sbmlName="Fpd";
  parameter_0000020_init.sbmlRole="derived";
  parameter_0000020.sbmlRole="parameter";
  parameter_0000020.sbmlName="OPvri";
  parameter_0000021_init.sbmlRole="derived";
  parameter_0000021.sbmlRole="parameter";
  parameter_0000021.sbmlName="OPper";
  parameter_0000022_init.sbmlRole="derived";
  parameter_0000022.sbmlRole="parameter";
  parameter_0000022.sbmlName="OPpdp";
  parameter_0000023.sbmlRole="parameter";
  parameter_0000023.sbmlName="Tvriop";
  parameter_0000024.sbmlRole="parameter";
  parameter_0000024.sbmlName="Tperop";
  parameter_0000025.sbmlRole="parameter";
  parameter_0000025.sbmlName="Tpdpop";
  parameter_0000026.sbmlRole="parameter";
  parameter_0000026.sbmlName="N";
  parameter_0000027.sbmlRole="parameter";
  parameter_0000027.sbmlName="Vper";
  parameter_0000028.sbmlRole="parameter";
  parameter_0000028.sbmlName="Vvri";
  parameter_0000029.sbmlRole="parameter";
  parameter_0000029.sbmlName="Vpdp";
  parameter_0000030.sbmlRole="parameter";
  parameter_0000030.sbmlName="Vclk";
  parameter_0000031.sbmlRole="parameter";
  parameter_0000031.sbmlName="Rpbas";
  parameter_0000032.sbmlRole="parameter";
  parameter_0000032.sbmlName="Rvbas";
  parameter_0000033.sbmlRole="parameter";
  parameter_0000033.sbmlName="Rcbas";
  parameter_0000034.sbmlRole="parameter";
  parameter_0000034.sbmlName="Rpdbas";
  parameter_0000036.sbmlRole="parameter";
  parameter_0000036.sbmlName="Vdclk";
  parameter_0000037.sbmlRole="parameter";
  parameter_0000037.sbmlName="vdvri";
  parameter_0000038.sbmlRole="parameter";
  parameter_0000038.sbmlName="vdpdp";
  parameter_0000039.sbmlRole="parameter";
  parameter_0000039.sbmlName="Tdelay";
  parameter_0000040.sbmlRole="parameter";
  parameter_0000040.sbmlName="Vpcyt";
  parameter_0000041.sbmlRole="parameter";
  parameter_0000041.sbmlName="Kpcyt";
  parameter_0000042.sbmlRole="parameter";
  parameter_0000042.sbmlName="Vpnuc";
  parameter_0000043.sbmlRole="parameter";
  parameter_0000043.sbmlName="Kpnuc";
  parameter_0000044.sbmlRole="parameter";
  parameter_0000044.sbmlName="Vtrans";
  parameter_0000045.sbmlRole="parameter";
  parameter_0000045.sbmlName="Ktrans";
  parameter_0000046.sbmlRole="parameter";
  parameter_0000046.sbmlName="Vdegp";
  parameter_0000047.sbmlRole="parameter";
  parameter_0000047.sbmlName="Kdegp";
  parameter_0000048.sbmlRole="parameter";
  parameter_0000048.sbmlName="kd";
  species_0000001.sbmlRole="species";
  species_0000001.sbmlCompartment="compartment_0000001";
  species_0000002.sbmlRole="species";
  species_0000002.sbmlCompartment="compartment_0000001";
  species_0000003.sbmlRole="species";
  species_0000003.sbmlCompartment="compartment_0000001";
  species_0000004.sbmlRole="species";
  species_0000004.sbmlCompartment="compartment_0000002";
  species_0000005.sbmlRole="species";
  species_0000005.sbmlCompartment="compartment_0000002";
  species_0000006.sbmlRole="species";
  species_0000006.sbmlCompartment="compartment_0000002";
  species_0000007.sbmlRole="species";
  species_0000007.sbmlCompartment="compartment_0000001";
  species_0000008.sbmlRole="species";
  species_0000008.sbmlCompartment="compartment_0000001";
  species_0000009.sbmlRole="species";
  species_0000009.sbmlCompartment="compartment_0000001";
  reaction_0000001.sbmlRole="rate";
  reaction_0000002.sbmlRole="rate";
  reaction_0000003.sbmlRole="rate";
  delayExpr0.sbmlRole="delay";
  reaction_0000004.sbmlRole="rate";
  reaction_0000005.sbmlRole="rate";
  reaction_0000006.sbmlRole="rate";
  reaction_0000007.sbmlRole="rate";
  reaction_0000008.sbmlRole="rate";
  reaction_0000009.sbmlRole="rate";
  reaction_0000010.sbmlRole="rate";
  reaction_0000011.sbmlRole="rate";
  reaction_0000012.sbmlRole="rate";
  reaction_0000013.sbmlRole="rate";
  reaction_0000014.sbmlRole="rate";
  reaction_0000015.sbmlRole="rate";
  reaction_0000016.sbmlRole="rate";
  reaction_0000017.sbmlRole="rate";
  reaction_0000018.sbmlRole="rate";
  reaction_0000019.sbmlRole="rate";
  reaction_0000020.sbmlRole="rate";
  reaction_0000021.sbmlRole="rate";
  reaction_0000022.sbmlRole="rate";
}