/* * Fibre Dispersion Law * * Model Structure * * Constitutive relations are fundamental to the solution of problems * in continuum mechanics, and are required in the study of, for * example, mechanically dominated clinical interventions involving * soft biological tissues. Structural continuum constitutive models * of arterial layers integrate information about the tissue morphology * and therefore allow investigation of the interrelation between * structure and function in response to mechanical loading. Collagen * fibres are key ingredients in the structure of arteries. In * the media (the middle layer of the artery wall) they are arranged * in two helically distributed families with a small pitch and * very little dispersion in their orientation (i.e. they are aligned * quite close to the circumferential direction). By contrast, * in the adventitial and intimal layers, the orientation of the * collagen fibres is dispersed, as shown by polarized light microscopy * of stained arterial tissue. As a result, continuum models that * do not account for the dispersion are not able to capture accurately * the stress-strain response of these layers. The purpose of this * paper, therefore, is to develop a structural continuum framework * that is able to represent the dispersion of the collagen fibre * orientation. This then allows the development of a new hyperelastic * free-energy function that is particularly suited for representing * the anisotropic elastic properties of adventitial and intimal * layers of arterial walls, and is a generalization of the fibre-reinforced * structural model introduced by Holzapfel and Gasser (Holzapfel * and Gasser 2001 Comput. Meth. Appl. Mech. Eng. 190, 4379-4403) * and Holzapfel et al. (Holzapfel et al. 2000 J. Elast. 61, 1-48). * The model incorporates an additional scalar structure parameter * that characterizes the dispersed collagen orientation. An efficient * finite element implementation of the model is then presented * and numerical examples show that the dispersion of the orientation * of collagen fibres in the adventitia of human iliac arteries * has a significant effect on their mechanical response. * * The original paper reference is cited below: * * Hyperelastic modelling of arterial layers with distributed collagen * fibre orientations, T.C. Gasser, R.W. Ogden and G.A. Holzapfel, * 2006, Journal of the Royal Society, 3(6), 15-35. PubMed ID: * 16849214 */ import nsrunit; unit conversion on; unit strain=1 dimensionless; unit stress=1 dimensionless; math main { //Warning: the following variables were set 'extern' or given // an initial value of '0' because the model would otherwise be // underdetermined: Emm, Emn, Ems, Enn, Ens, Ess extern real Emm strain; extern real Emn strain; extern real Ems strain; extern real Enn strain; extern real Ens strain; extern real Ess strain; real c11 strain; c11=0; real c12 strain; c12=0; real c21 strain; c21=0; real c22 strain; c22=0; real c41 strain; c41=0; real c42 strain; c42=0; real c81 strain; c81=0; real c82 strain; c82=0; real kappa1 strain; kappa1=0; real kappa2 strain; kappa2=0; real Tdevmm stress; real Tdevmn stress; real Tdevms stress; real Tdevnn stress; real Tdevns stress; real Tdevss stress; real I1 strain; real I2 strain; real I4 strain; real I6 strain; real I8 strain; // // I1=(3+2*Emm+2*Enn+2*Ess); I2=(3+(-4)*Emn*Emn+4*Enn+(-4)*Ems*Ems+(-4)*Ens*Ens+4*(1+Enn)*Ess+4*(1+Enn)*Ess+4*(1+Enn+Ess)*Emm); I4=(1+2*Emm); I6=(1+2*Enn); I8=(1+2*Ess); Tdevmm=(2*c11*exp(c12*(I1-3)^2)*(I1-3)+4*c21*exp(c22*(I2-3)^2)*(I2-3)*(1+Enn+Ess)+2*c41*exp(c42*(I4*(1-3*kappa1)-1)^2)*(I4*(1-3*kappa1)-1)*(1-3*kappa1)); Tdevmn=((-4)*c21*exp(c22*(I2-3)^2)*(I2-3)*Emn); Tdevms=((-4)*c21*exp(c22*(I2-3)^2)*(I2-3)*Ems); Tdevnn=(2*c11*exp(c12*(I1-3)^2)*(I1-3)+4*c21*exp(c22*(I2-3)^2)*(I2-3)*(1+Emm+Ess)); Tdevss=(2*c11*exp(c12*(I1-3)^2)*(I1-3)+4*c21*exp(c22*(I2-3)^2)*(I2-3)*(1+Emm+Enn)+2*c81*exp(c82*(I8*(1-3*kappa2)-1)^2)*(I8*(1-3*kappa2)-1)*(1-3*kappa2)); Tdevns=((-4)*c21*exp(c22*(I2-3)^2)*(I2-3)*Ens); }