/* * Limit cycle models for circadian rhythms based on transcriptional * regulation in Drosophila and Neurospora * * Model Status * * This is an import for the model "leloup_1999_1.1model.cellml". * It is used to define a reoccuring structure within the model * and may be used for multiple equations in the model. This file * is known to run only in OpenCell in conjunction with the base * file. * * Model Structure * * The original paper reference is cited below: * * Limit Cycle Models for Circadian Rhythms Based on Transcriptional * Regulation in Drosophila and Neurospora, Jean-Christophe Leloup, * Didier Gonze, and Albert Goldbeter, 1999, Journal of Biological * Rhythms, 14, 433-448. PubMed ID: 10643740 */ import nsrunit; unit conversion on; // unit nanomolar predefined unit hour=3600 second^1; unit flux=2.7777778E-10 meter^(-3)*second^(-1)*mole^1; unit first_order_rate_constant=2.7777778E-4 second^(-1); unit second_order_rate_constant=2.7777778E2 meter^3*second^(-1)*mole^(-1); math main { //Warning: the following variables were set 'extern' or given // an initial value of '0' because the model would otherwise be // underdetermined: Y0, Y1, Y2, C, CN extern real Y0 nanomolar; extern real Y1 nanomolar; extern real Y2 nanomolar; extern real C nanomolar; extern real CN nanomolar; real Yt nanomolar; // Yt=(Y0+Y1+Y2+C+CN); }