// This model generated automatically from SBML

// unit definitions
import nsrunit;
unit conversion off;

// SBML property definitions
property sbmlRole=string;
property sbmlName=string;
property sbmlCompartment=string;

// SBML reactions
// R01415: space_5_space_6_minus_Dihydrothymine => Thymine 
// R00963: UMP <=> Uridine 
// R02101: dUMP <=> dTMP 
// R01993: space_S_space_minus_Dihydroorotate => N_minus_Carbamoyl_minus_L_minus_aspartate 
// R01569: dTMP <=> Thymidine 
// R02325: dCTP <=> dUTP 
// R02093: dTDP => dTTP 
// R00156: UDP => UTP 
// R01870: Orotidine_space_5_space_minus_phosphate => Orotate space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate 
// R02269: space_5_space_6_minus_Dihydrouracil => space_3_minus_Ureidopropionate 
// R02018: dUDP Thioredoxin_space_disulfide <=> UDP Thioredoxin 
// R01867: space_S_space_minus_Dihydroorotate => Orotate 
// R03929: space_2_space_space_3_space_minus_Cyclic_space_CMP <=> space_3_space_minus_CMP 
// R01665: dCMP <=> dCDP 
// R00570: CDP => CTP 
// R02094: dTMP => dTDP 
// R00442: CTP => RNA 
// R00377: dCTP => DNA 
// R01664: dCMP <=> Deoxycytidine 
// R00438: RNA => UDP 
// R03538: space_2_space_space_3_space_minus_Cyclic_space_UMP <=> space_3_space_minus_UMP 
// R00575: L_minus_Glutamine <=> Carbamoyl_space_phosphate 
// R01397: Carbamoyl_space_phosphate <=> N_minus_Carbamoyl_minus_L_minus_aspartate 
// R00571: UTP <=> CTP 
// R00978: space_5_space_6_minus_Dihydrouracil => Uracil 
// R03055: space_5_space_6_minus_Dihydrothymine => space_3_minus_Ureidoisobutyrate 
// R00965: Orotidine_space_5_space_minus_phosphate <=> UMP 
// R00511: CMP <=> Cytidine 
// R02331: dUDP => dUTP 
// R00158: UMP => UDP 
// R02100: dUTP <=> dUMP 
// R00443: UTP => RNA 
// R02024: dCDP Thioredoxin_space_disulfide <=> CDP Thioredoxin 
// R02098: dUMP => dUDP 
// R00378: dTTP => DNA 
// R02326: dCDP => dCTP 
// R00568: CTP <=> UTP 
// R02016: Thioredoxin_space_disulfide <=> Thioredoxin 
// R00512: CMP => CDP 
// R00966: UMP => Uracil 
// R00440: RNA => CDP 

math main {
  realDomain time second;
  time.min=0;
  extern time.max;
  extern time.delta;

  // variable definitions
  real default = 1 L;
  real uVol = 1 L;
  real E1_space_8_space_1_space_9 = 0 M;
  real E3_space_5_space_2_space_3 = 0 M;
  real E2_space_7_space_7_space_7 = 0 M;
  real E2_space_7_space_7_space_8 = 0 M;
  real E2_space_7_space_7_space_6 = 0 M;
  real E3_space_5_space_4_space_13 = 0 M;
  real E1_space_3_space_3_space_1 = 0 M;
  real E6_space_3_space_4_space_2 = 0 M;
  real E2_space_7_space_4_space_6 = 0 M;
  real E2_space_4_space_2_space_10 = 0 M;
  real E3_space_6_space_1_space_23 = 0 M;
  real E1_space_17_space_4_space_1 = 0 M;
  real E2_space_7_space_4_space_9 = 0 M;
  real E2_space_7_space_4_space_14 = 0 M;
  real E2_space_7_space_4_space_22 = 0 M;
  real E4_space_1_space_1_space_23 = 0 M;
  real E3_space_1_space_4_space_16 = 0 M;
  real E2_space_1_space_1_space_45 = 0 M;
  real E3_space_1_space_3_space_5 = 0 M;
  real E2_space_4_space_2_space_9 = 0 M;
  real E1_space_3_space_1_space_2 = 0 M;
  real E3_space_5_space_2_space_2 = 0 M;
  real E2_space_1_space_3_space_2 = 0 M;
  real E6_space_3_space_5_space_5 = 0 M;
  real space_3_minus_Ureidopropionate(time) M;
  real N_minus_Carbamoyl_minus_L_minus_aspartate(time) M;
  real Carbamoyl_space_phosphate(time) M;
  real L_minus_Glutamine(time) M;
  real Thioredoxin(time) M;
  real Thioredoxin_space_disulfide(time) M;
  real space_S_space_minus_Dihydroorotate(time) M;
  real RNA(time) M;
  real DNA(time) M;
  real CTP(time) M;
  real dCTP(time) M;
  real dUTP(time) M;
  real dTTP(time) M;
  real UTP(time) M;
  real Orotate(time) M;
  real space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate(time) M;
  real UDP(time) M;
  real CDP(time) M;
  real dUDP(time) M;
  real dTDP(time) M;
  real dCDP(time) M;
  real Orotidine_space_5_space_minus_phosphate(time) M;
  real space_2_space_space_3_space_minus_Cyclic_space_CMP(time) M;
  real dUMP(time) M;
  real CMP(time) M;
  real dCMP(time) M;
  real dTMP(time) M;
  real UMP(time) M;
  real space_3_space_minus_CMP(time) M;
  real Deoxycytidine(time) M;
  real Thymidine(time) M;
  real Uridine(time) M;
  real Cytidine(time) M;
  real space_3_space_minus_UMP(time) M;
  real Thymine(time) M;
  real space_2_space_space_3_space_minus_Cyclic_space_UMP(time) M;
  real Uracil(time) M;
  real space_5_space_6_minus_Dihydrothymine(time) M;
  real space_5_space_6_minus_Dihydrouracil(time) M;
  real space_3_minus_Ureidoisobutyrate(time) M;
  real R01415(time) katal;
  extern real R01415.kf;
  extern real R01415.kb;
  real R00963(time) katal;
  extern real R00963.kf;
  extern real R00963.kb;
  real R02101(time) katal;
  extern real R02101.kf;
  extern real R02101.kb;
  real R01993(time) katal;
  extern real R01993.kf;
  extern real R01993.kb;
  real R01569(time) katal;
  extern real R01569.kf;
  extern real R01569.kb;
  real R02325(time) katal;
  extern real R02325.kf;
  extern real R02325.kb;
  real R02093(time) katal;
  extern real R02093.kf;
  extern real R02093.kb;
  real R00156(time) katal;
  extern real R00156.kf;
  extern real R00156.kb;
  real R01870(time) katal;
  extern real R01870.kf;
  extern real R01870.kb;
  real R02269(time) katal;
  extern real R02269.kf;
  extern real R02269.kb;
  real R02018(time) katal;
  extern real R02018.kf;
  extern real R02018.kb;
  real R01867(time) katal;
  extern real R01867.kf;
  extern real R01867.kb;
  real R03929(time) katal;
  extern real R03929.kf;
  extern real R03929.kb;
  real R01665(time) katal;
  extern real R01665.kf;
  extern real R01665.kb;
  real R00570(time) katal;
  extern real R00570.kf;
  extern real R00570.kb;
  real R02094(time) katal;
  extern real R02094.kf;
  extern real R02094.kb;
  real R00442(time) katal;
  extern real R00442.kf;
  extern real R00442.kb;
  real R00377(time) katal;
  extern real R00377.kf;
  extern real R00377.kb;
  real R01664(time) katal;
  extern real R01664.kf;
  extern real R01664.kb;
  real R00438(time) katal;
  extern real R00438.kf;
  extern real R00438.kb;
  real R03538(time) katal;
  extern real R03538.kf;
  extern real R03538.kb;
  real R00575(time) katal;
  extern real R00575.kf;
  extern real R00575.kb;
  real R01397(time) katal;
  extern real R01397.kf;
  extern real R01397.kb;
  real R00571(time) katal;
  extern real R00571.kf;
  extern real R00571.kb;
  real R00978(time) katal;
  extern real R00978.kf;
  extern real R00978.kb;
  real R03055(time) katal;
  extern real R03055.kf;
  extern real R03055.kb;
  real R00965(time) katal;
  extern real R00965.kf;
  extern real R00965.kb;
  real R00511(time) katal;
  extern real R00511.kf;
  extern real R00511.kb;
  real R02331(time) katal;
  extern real R02331.kf;
  extern real R02331.kb;
  real R00158(time) katal;
  extern real R00158.kf;
  extern real R00158.kb;
  real R02100(time) katal;
  extern real R02100.kf;
  extern real R02100.kb;
  real R00443(time) katal;
  extern real R00443.kf;
  extern real R00443.kb;
  real R02024(time) katal;
  extern real R02024.kf;
  extern real R02024.kb;
  real R02098(time) katal;
  extern real R02098.kf;
  extern real R02098.kb;
  real R00378(time) katal;
  extern real R00378.kf;
  extern real R00378.kb;
  real R02326(time) katal;
  extern real R02326.kf;
  extern real R02326.kb;
  real R00568(time) katal;
  extern real R00568.kf;
  extern real R00568.kb;
  real R02016(time) katal;
  extern real R02016.kf;
  extern real R02016.kb;
  real R00512(time) katal;
  extern real R00512.kf;
  extern real R00512.kb;
  real R00966(time) katal;
  extern real R00966.kf;
  extern real R00966.kb;
  real R00440(time) katal;
  extern real R00440.kf;
  extern real R00440.kb;

  // equations
  when (time=time.min) space_3_minus_Ureidopropionate = 0;
  space_3_minus_Ureidopropionate:time = (R02269)/uVol;
  when (time=time.min) N_minus_Carbamoyl_minus_L_minus_aspartate = 0;
  N_minus_Carbamoyl_minus_L_minus_aspartate:time = (R01993 + R01397)/uVol;
  when (time=time.min) Carbamoyl_space_phosphate = 0;
  Carbamoyl_space_phosphate:time = (R00575 + -1*R01397)/uVol;
  when (time=time.min) L_minus_Glutamine = 0;
  L_minus_Glutamine:time = (-1*R00575)/uVol;
  when (time=time.min) Thioredoxin = 0;
  Thioredoxin:time = (R02018 + R02024 + R02016)/uVol;
  when (time=time.min) Thioredoxin_space_disulfide = 0;
  Thioredoxin_space_disulfide:time = (-1*R02018 + -1*R02024 + -1*R02016)/uVol;
  when (time=time.min) space_S_space_minus_Dihydroorotate = 0;
  space_S_space_minus_Dihydroorotate:time = (-1*R01993 + -1*R01867)/uVol;
  when (time=time.min) RNA = 0;
  RNA:time = (R00442 + -1*R00438 + R00443 + -1*R00440)/uVol;
  when (time=time.min) DNA = 0;
  DNA:time = (R00377 + R00378)/uVol;
  when (time=time.min) CTP = 0;
  CTP:time = (R00570 + -1*R00442 + R00571 + -1*R00568)/uVol;
  when (time=time.min) dCTP = 0;
  dCTP:time = (-1*R02325 + -1*R00377 + R02326)/uVol;
  when (time=time.min) dUTP = 0;
  dUTP:time = (R02325 + R02331 + -1*R02100)/uVol;
  when (time=time.min) dTTP = 0;
  dTTP:time = (R02093 + -1*R00378)/uVol;
  when (time=time.min) UTP = 0;
  UTP:time = (R00156 + -1*R00571 + -1*R00443 + R00568)/uVol;
  when (time=time.min) Orotate = 0;
  Orotate:time = (R01870 + R01867)/uVol;
  when (time=time.min) space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate = 0;
  space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate:time = (R01870)/uVol;
  when (time=time.min) UDP = 0;
  UDP:time = (-1*R00156 + R02018 + R00438 + R00158)/uVol;
  when (time=time.min) CDP = 0;
  CDP:time = (-1*R00570 + R02024 + R00512 + R00440)/uVol;
  when (time=time.min) dUDP = 0;
  dUDP:time = (-1*R02018 + -1*R02331 + R02098)/uVol;
  when (time=time.min) dTDP = 0;
  dTDP:time = (-1*R02093 + R02094)/uVol;
  when (time=time.min) dCDP = 0;
  dCDP:time = (R01665 + -1*R02024 + -1*R02326)/uVol;
  when (time=time.min) Orotidine_space_5_space_minus_phosphate = 0;
  Orotidine_space_5_space_minus_phosphate:time = (-1*R01870 + -1*R00965)/uVol;
  when (time=time.min) space_2_space_space_3_space_minus_Cyclic_space_CMP = 0;
  space_2_space_space_3_space_minus_Cyclic_space_CMP:time = (-1*R03929)/uVol;
  when (time=time.min) dUMP = 0;
  dUMP:time = (-1*R02101 + R02100 + -1*R02098)/uVol;
  when (time=time.min) CMP = 0;
  CMP:time = (-1*R00511 + -1*R00512)/uVol;
  when (time=time.min) dCMP = 0;
  dCMP:time = (-1*R01665 + -1*R01664)/uVol;
  when (time=time.min) dTMP = 0;
  dTMP:time = (R02101 + -1*R01569 + -1*R02094)/uVol;
  when (time=time.min) UMP = 0;
  UMP:time = (-1*R00963 + R00965 + -1*R00158 + -1*R00966)/uVol;
  when (time=time.min) space_3_space_minus_CMP = 0;
  space_3_space_minus_CMP:time = (R03929)/uVol;
  when (time=time.min) Deoxycytidine = 0;
  Deoxycytidine:time = (R01664)/uVol;
  when (time=time.min) Thymidine = 0;
  Thymidine:time = (R01569)/uVol;
  when (time=time.min) Uridine = 0;
  Uridine:time = (R00963)/uVol;
  when (time=time.min) Cytidine = 0;
  Cytidine:time = (R00511)/uVol;
  when (time=time.min) space_3_space_minus_UMP = 0;
  space_3_space_minus_UMP:time = (R03538)/uVol;
  when (time=time.min) Thymine = 0;
  Thymine:time = (R01415)/uVol;
  when (time=time.min) space_2_space_space_3_space_minus_Cyclic_space_UMP = 0;
  space_2_space_space_3_space_minus_Cyclic_space_UMP:time = (-1*R03538)/uVol;
  when (time=time.min) Uracil = 0;
  Uracil:time = (R00978 + R00966)/uVol;
  when (time=time.min) space_5_space_6_minus_Dihydrothymine = 0;
  space_5_space_6_minus_Dihydrothymine:time = (-1*R01415 + -1*R03055)/uVol;
  when (time=time.min) space_5_space_6_minus_Dihydrouracil = 0;
  space_5_space_6_minus_Dihydrouracil:time = (-1*R02269 + -1*R00978)/uVol;
  when (time=time.min) space_3_minus_Ureidoisobutyrate = 0;
  space_3_minus_Ureidoisobutyrate:time = (R03055)/uVol;
  R01415 = R01415.kf*space_5_space_6_minus_Dihydrothymine - R01415.kb*Thymine;
  R00963 = R00963.kf*UMP - R00963.kb*Uridine;
  R02101 = R02101.kf*dUMP - R02101.kb*dTMP;
  R01993 = R01993.kf*space_S_space_minus_Dihydroorotate - R01993.kb*N_minus_Carbamoyl_minus_L_minus_aspartate;
  R01569 = R01569.kf*dTMP - R01569.kb*Thymidine;
  R02325 = R02325.kf*dCTP - R02325.kb*dUTP;
  R02093 = R02093.kf*dTDP - R02093.kb*dTTP;
  R00156 = R00156.kf*UDP - R00156.kb*UTP;
  R01870 = R01870.kf*Orotidine_space_5_space_minus_phosphate - R01870.kb*Orotate*space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate;
  R02269 = R02269.kf*space_5_space_6_minus_Dihydrouracil - R02269.kb*space_3_minus_Ureidopropionate;
  R02018 = R02018.kf*dUDP*Thioredoxin_space_disulfide - R02018.kb*UDP*Thioredoxin;
  R01867 = R01867.kf*space_S_space_minus_Dihydroorotate - R01867.kb*Orotate;
  R03929 = R03929.kf*space_2_space_space_3_space_minus_Cyclic_space_CMP - R03929.kb*space_3_space_minus_CMP;
  R01665 = R01665.kf*dCMP - R01665.kb*dCDP;
  R00570 = R00570.kf*CDP - R00570.kb*CTP;
  R02094 = R02094.kf*dTMP - R02094.kb*dTDP;
  R00442 = R00442.kf*CTP - R00442.kb*RNA;
  R00377 = R00377.kf*dCTP - R00377.kb*DNA;
  R01664 = R01664.kf*dCMP - R01664.kb*Deoxycytidine;
  R00438 = R00438.kf*RNA - R00438.kb*UDP;
  R03538 = R03538.kf*space_2_space_space_3_space_minus_Cyclic_space_UMP - R03538.kb*space_3_space_minus_UMP;
  R00575 = R00575.kf*L_minus_Glutamine - R00575.kb*Carbamoyl_space_phosphate;
  R01397 = R01397.kf*Carbamoyl_space_phosphate - R01397.kb*N_minus_Carbamoyl_minus_L_minus_aspartate;
  R00571 = R00571.kf*UTP - R00571.kb*CTP;
  R00978 = R00978.kf*space_5_space_6_minus_Dihydrouracil - R00978.kb*Uracil;
  R03055 = R03055.kf*space_5_space_6_minus_Dihydrothymine - R03055.kb*space_3_minus_Ureidoisobutyrate;
  R00965 = R00965.kf*Orotidine_space_5_space_minus_phosphate - R00965.kb*UMP;
  R00511 = R00511.kf*CMP - R00511.kb*Cytidine;
  R02331 = R02331.kf*dUDP - R02331.kb*dUTP;
  R00158 = R00158.kf*UMP - R00158.kb*UDP;
  R02100 = R02100.kf*dUTP - R02100.kb*dUMP;
  R00443 = R00443.kf*UTP - R00443.kb*RNA;
  R02024 = R02024.kf*dCDP*Thioredoxin_space_disulfide - R02024.kb*CDP*Thioredoxin;
  R02098 = R02098.kf*dUMP - R02098.kb*dUDP;
  R00378 = R00378.kf*dTTP - R00378.kb*DNA;
  R02326 = R02326.kf*dCDP - R02326.kb*dCTP;
  R00568 = R00568.kf*CTP - R00568.kb*UTP;
  R02016 = R02016.kf*Thioredoxin_space_disulfide - R02016.kb*Thioredoxin;
  R00512 = R00512.kf*CMP - R00512.kb*CDP;
  R00966 = R00966.kf*UMP - R00966.kb*Uracil;
  R00440 = R00440.kf*RNA - R00440.kb*CDP;

  // variable properties
  default.sbmlRole="compartment";
  uVol.sbmlRole="compartment";
  E1_space_8_space_1_space_9.sbmlRole="species";
  E1_space_8_space_1_space_9.sbmlCompartment="uVol";
  E3_space_5_space_2_space_3.sbmlRole="species";
  E3_space_5_space_2_space_3.sbmlCompartment="uVol";
  E2_space_7_space_7_space_7.sbmlRole="species";
  E2_space_7_space_7_space_7.sbmlCompartment="uVol";
  E2_space_7_space_7_space_8.sbmlRole="species";
  E2_space_7_space_7_space_8.sbmlCompartment="uVol";
  E2_space_7_space_7_space_6.sbmlRole="species";
  E2_space_7_space_7_space_6.sbmlCompartment="uVol";
  E3_space_5_space_4_space_13.sbmlRole="species";
  E3_space_5_space_4_space_13.sbmlCompartment="uVol";
  E1_space_3_space_3_space_1.sbmlRole="species";
  E1_space_3_space_3_space_1.sbmlCompartment="uVol";
  E6_space_3_space_4_space_2.sbmlRole="species";
  E6_space_3_space_4_space_2.sbmlCompartment="uVol";
  E2_space_7_space_4_space_6.sbmlRole="species";
  E2_space_7_space_4_space_6.sbmlCompartment="uVol";
  E2_space_4_space_2_space_10.sbmlRole="species";
  E2_space_4_space_2_space_10.sbmlCompartment="uVol";
  E3_space_6_space_1_space_23.sbmlRole="species";
  E3_space_6_space_1_space_23.sbmlCompartment="uVol";
  E1_space_17_space_4_space_1.sbmlRole="species";
  E1_space_17_space_4_space_1.sbmlCompartment="uVol";
  E2_space_7_space_4_space_9.sbmlRole="species";
  E2_space_7_space_4_space_9.sbmlCompartment="uVol";
  E2_space_7_space_4_space_14.sbmlRole="species";
  E2_space_7_space_4_space_14.sbmlCompartment="uVol";
  E2_space_7_space_4_space_22.sbmlRole="species";
  E2_space_7_space_4_space_22.sbmlCompartment="uVol";
  E4_space_1_space_1_space_23.sbmlRole="species";
  E4_space_1_space_1_space_23.sbmlCompartment="uVol";
  E3_space_1_space_4_space_16.sbmlRole="species";
  E3_space_1_space_4_space_16.sbmlCompartment="uVol";
  E2_space_1_space_1_space_45.sbmlRole="species";
  E2_space_1_space_1_space_45.sbmlCompartment="uVol";
  E3_space_1_space_3_space_5.sbmlRole="species";
  E3_space_1_space_3_space_5.sbmlCompartment="uVol";
  E2_space_4_space_2_space_9.sbmlRole="species";
  E2_space_4_space_2_space_9.sbmlCompartment="uVol";
  E1_space_3_space_1_space_2.sbmlRole="species";
  E1_space_3_space_1_space_2.sbmlCompartment="uVol";
  E3_space_5_space_2_space_2.sbmlRole="species";
  E3_space_5_space_2_space_2.sbmlCompartment="uVol";
  E2_space_1_space_3_space_2.sbmlRole="species";
  E2_space_1_space_3_space_2.sbmlCompartment="uVol";
  E6_space_3_space_5_space_5.sbmlRole="species";
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