// This model generated automatically from SBML

// unit definitions
import nsrunit;
unit conversion off;

// SBML property definitions
property sbmlRole=string;
property sbmlName=string;
property sbmlCompartment=string;

// SBML reactions
// R03408: space_3_beta_minus_Hydroxyandrost_minus_5_minus_en_minus_17_minus_one <=> space_16_alpha_minus_Hydroxydehydroepiandrosterone 
// R04764: space_2_minus_Hydroxyestradiol_minus_17beta <=> space_2_minus_Methoxyestradiol_minus_17beta 
// R03980: Estrone <=> Estrone_space_3_minus_sulfate 

math main {
  realDomain time second;
  time.min=0;
  extern time.max;
  extern time.delta;

  // variable definitions
  real default = 1 L;
  real uVol = 1 L;
  real E1_space_14_space_99_space_minus_ = 0 M;
  real E2_space_1_space_1_space_minus_ = 0 M;
  real E3_space_1_space_6_space_1 = 0 M;
  real Estrone_space_3_minus_sulfate(time) M;
  real space_3_beta_minus_Hydroxyandrost_minus_5_minus_en_minus_17_minus_one(time) M;
  real Estrone(time) M;
  real space_16_alpha_minus_Hydroxydehydroepiandrosterone(time) M;
  real space_2_minus_Hydroxyestradiol_minus_17beta(time) M;
  real space_2_minus_Methoxyestradiol_minus_17beta(time) M;
  real R03408(time) katal;
  extern real R03408.kf;
  extern real R03408.kb;
  real R04764(time) katal;
  extern real R04764.kf;
  extern real R04764.kb;
  real R03980(time) katal;
  extern real R03980.kf;
  extern real R03980.kb;

  // equations
  when (time=time.min) Estrone_space_3_minus_sulfate = 0;
  Estrone_space_3_minus_sulfate:time = (R03980)/uVol;
  when (time=time.min) space_3_beta_minus_Hydroxyandrost_minus_5_minus_en_minus_17_minus_one = 0;
  space_3_beta_minus_Hydroxyandrost_minus_5_minus_en_minus_17_minus_one:time = (-1*R03408)/uVol;
  when (time=time.min) Estrone = 0;
  Estrone:time = (-1*R03980)/uVol;
  when (time=time.min) space_16_alpha_minus_Hydroxydehydroepiandrosterone = 0;
  space_16_alpha_minus_Hydroxydehydroepiandrosterone:time = (R03408)/uVol;
  when (time=time.min) space_2_minus_Hydroxyestradiol_minus_17beta = 0;
  space_2_minus_Hydroxyestradiol_minus_17beta:time = (-1*R04764)/uVol;
  when (time=time.min) space_2_minus_Methoxyestradiol_minus_17beta = 0;
  space_2_minus_Methoxyestradiol_minus_17beta:time = (R04764)/uVol;
  R03408 = R03408.kf*space_3_beta_minus_Hydroxyandrost_minus_5_minus_en_minus_17_minus_one - R03408.kb*space_16_alpha_minus_Hydroxydehydroepiandrosterone;
  R04764 = R04764.kf*space_2_minus_Hydroxyestradiol_minus_17beta - R04764.kb*space_2_minus_Methoxyestradiol_minus_17beta;
  R03980 = R03980.kf*Estrone - R03980.kb*Estrone_space_3_minus_sulfate;

  // variable properties
  default.sbmlRole="compartment";
  uVol.sbmlRole="compartment";
  E1_space_14_space_99_space_minus_.sbmlRole="species";
  E1_space_14_space_99_space_minus_.sbmlCompartment="uVol";
  E2_space_1_space_1_space_minus_.sbmlRole="species";
  E2_space_1_space_1_space_minus_.sbmlCompartment="uVol";
  E3_space_1_space_6_space_1.sbmlRole="species";
  E3_space_1_space_6_space_1.sbmlCompartment="uVol";
  Estrone_space_3_minus_sulfate.sbmlRole="species";
  Estrone_space_3_minus_sulfate.sbmlCompartment="uVol";
  space_3_beta_minus_Hydroxyandrost_minus_5_minus_en_minus_17_minus_one.sbmlRole="species";
  space_3_beta_minus_Hydroxyandrost_minus_5_minus_en_minus_17_minus_one.sbmlCompartment="uVol";
  Estrone.sbmlRole="species";
  Estrone.sbmlCompartment="uVol";
  space_16_alpha_minus_Hydroxydehydroepiandrosterone.sbmlRole="species";
  space_16_alpha_minus_Hydroxydehydroepiandrosterone.sbmlCompartment="uVol";
  space_2_minus_Hydroxyestradiol_minus_17beta.sbmlRole="species";
  space_2_minus_Hydroxyestradiol_minus_17beta.sbmlCompartment="uVol";
  space_2_minus_Methoxyestradiol_minus_17beta.sbmlRole="species";
  space_2_minus_Methoxyestradiol_minus_17beta.sbmlCompartment="uVol";
  R03408.sbmlRole="rate";
  R03408.kf.sbmlRole="rate";
  R03408.kb.sbmlRole="rate";
  R04764.sbmlRole="rate";
  R04764.kf.sbmlRole="rate";
  R04764.kb.sbmlRole="rate";
  R03980.sbmlRole="rate";
  R03980.kf.sbmlRole="rate";
  R03980.kb.sbmlRole="rate";
}