// This model generated automatically from SBML

// unit definitions
import nsrunit;
unit conversion off;

// SBML property definitions
property sbmlRole=string;
property sbmlName=string;
property sbmlCompartment=string;

// SBML reactions
// R04209: space_1_minus_space_5_minus_Phospho_minus_D_minus_ribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxylate => Aminoimidazole_space_ribotide 
// R04325: space_5_space_minus_Phosphoribosylglycinamide <=> space_5_space_minus_Phosphoribosyl_minus_N_minus_formylglycinamide 
// R01049: D_minus_Ribose_space_5_minus_phosphate <=> space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate 
// R00127: AMP => ADP 
// R00376: dGTP => DNA 
// R00124: ADP => ATP 
// R04560: space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxamide <=> space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_formamido_minus_4_minus_imidazolecarboxamide 
// R03530: dIDP => dITP 
// R04463: space_5_space_minus_Phosphoribosyl_minus_N_minus_formylglycinamide <=> space_2_minus_space_Formamido_space_minus_N1_minus_space_5_space_minus_phosphoribosyl_space_acetamidine 
// R00441: GTP => RNA 
// R00435: ATP => RNA 
// R00183: AMP <=> Adenosine 
// R01857: dGDP => dGTP 
// R00330: GDP => GTP 
// R02088: dAMP => Deoxyadenosine 
// R01083: N6_minus_space_1_space_2_minus_Dicarboxyethyl_space_minus_AMP <=> AMP 
// R01227: GMP <=> Guanosine 
// R04591: space_1_minus_space_5_minus_Phospho_minus_D_minus_ribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxylate => space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_space_N_minus_succinocarboxamide_space_minus_imidazole 
// R02719: Xanthosine_space_5_space_minus_phosphate <=> Xanthosine 
// R02090: dGMP => dGDP 
// R02017: dADP <=> ADP 
// R00332: GMP => GDP 
// R01137: dADP => dATP 
// R01968: dGMP => Deoxyguanosine 
// R01547: dAMP => dADP 
// R01130: IMP => Xanthosine_space_5_space_minus_phosphate 
// R00722: IDP => ITP 
// R02019: dGDP <=> GDP 
// R04144: space_5_minus_Phosphoribosylamine <=> space_5_space_minus_Phosphoribosylglycinamide 
// R00439: RNA => GDP 
// R01072: space_5_minus_Phosphoribosylamine <=> space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate L_minus_Glutamine 
// R04208: space_2_minus_space_Formamido_space_minus_N1_minus_space_5_space_minus_phosphoribosyl_space_acetamidine <=> Aminoimidazole_space_ribotide 
// R00375: dATP => DNA 
// R01135: IMP <=> N6_minus_space_1_space_2_minus_Dicarboxyethyl_space_minus_AMP 
// R01126: IMP <=> Inosine 
// R00437: RNA => ADP 
// R01127: space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_formamido_minus_4_minus_imidazolecarboxamide => IMP 
// R04559: space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_space_N_minus_succinocarboxamide_space_minus_imidazole => space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxamide 
// R01230: Xanthosine_space_5_space_minus_phosphate <=> GMP 

math main {
  realDomain time second;
  time.min=0;
  extern time.max;
  extern time.delta;

  // variable definitions
  real default = 1 L;
  real uVol = 1 L;
  real E2_space_7_space_4_space_8 = 0 M;
  real E1_space_17_space_4_space_1 = 0 M;
  real E2_space_7_space_4_space_6 = 0 M;
  real E3_space_1_space_3_space_5 = 0 M;
  real E2_space_7_space_7_space_7 = 0 M;
  real E2_space_7_space_7_space_8 = 0 M;
  real E2_space_7_space_7_space_6 = 0 M;
  real E2_space_7_space_4_space_3 = 0 M;
  real E2_space_7_space_6_space_1 = 0 M;
  real E2_space_4_space_2_space_14 = 0 M;
  real E4_space_3_space_2_space_2 = 0 M;
  real E6_space_3_space_4_space_13 = 0 M;
  real E2_space_1_space_2_space_3 = 0 M;
  real E3_space_5_space_4_space_10 = 0 M;
  real E6_space_3_space_4_space_4 = 0 M;
  real E2_space_1_space_2_space_2 = 0 M;
  real E1_space_1_space_1_space_205 = 0 M;
  real E6_space_3_space_5_space_3 = 0 M;
  real E6_space_3_space_2_space_6 = 0 M;
  real E6_space_3_space_5_space_2 = 0 M;
  real E6_space_3_space_3_space_1 = 0 M;
  real E4_space_1_space_1_space_21 = 0 M;
  real GDP(time) M;
  real dGDP(time) M;
  real dGMP(time) M;
  real dIDP(time) M;
  real GTP(time) M;
  real dGTP(time) M;
  real dITP(time) M;
  real Deoxyguanosine(time) M;
  real RNA(time) M;
  real DNA(time) M;
  real Deoxyadenosine(time) M;
  real ATP(time) M;
  real dATP(time) M;
  real ADP(time) M;
  real dADP(time) M;
  real dAMP(time) M;
  real D_minus_Ribose_space_5_minus_phosphate(time) M;
  real space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate(time) M;
  real L_minus_Glutamine(time) M;
  real AMP(time) M;
  real Adenosine(time) M;
  real space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_formamido_minus_4_minus_imidazolecarboxamide(time) M;
  real space_5_minus_Phosphoribosylamine(time) M;
  real N6_minus_space_1_space_2_minus_Dicarboxyethyl_space_minus_AMP(time) M;
  real space_5_space_minus_Phosphoribosylglycinamide(time) M;
  real space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxamide(time) M;
  real IMP(time) M;
  real Inosine(time) M;
  real space_5_space_minus_Phosphoribosyl_minus_N_minus_formylglycinamide(time) M;
  real space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_space_N_minus_succinocarboxamide_space_minus_imidazole(time) M;
  real IDP(time) M;
  real Xanthosine_space_5_space_minus_phosphate(time) M;
  real Xanthosine(time) M;
  real space_2_minus_space_Formamido_space_minus_N1_minus_space_5_space_minus_phosphoribosyl_space_acetamidine(time) M;
  real ITP(time) M;
  real space_1_minus_space_5_minus_Phospho_minus_D_minus_ribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxylate(time) M;
  real GMP(time) M;
  real Guanosine(time) M;
  real Aminoimidazole_space_ribotide(time) M;
  real R04209(time) katal;
  extern real R04209.kf;
  extern real R04209.kb;
  real R04325(time) katal;
  extern real R04325.kf;
  extern real R04325.kb;
  real R01049(time) katal;
  extern real R01049.kf;
  extern real R01049.kb;
  real R00127(time) katal;
  extern real R00127.kf;
  extern real R00127.kb;
  real R00376(time) katal;
  extern real R00376.kf;
  extern real R00376.kb;
  real R00124(time) katal;
  extern real R00124.kf;
  extern real R00124.kb;
  real R04560(time) katal;
  extern real R04560.kf;
  extern real R04560.kb;
  real R03530(time) katal;
  extern real R03530.kf;
  extern real R03530.kb;
  real R04463(time) katal;
  extern real R04463.kf;
  extern real R04463.kb;
  real R00441(time) katal;
  extern real R00441.kf;
  extern real R00441.kb;
  real R00435(time) katal;
  extern real R00435.kf;
  extern real R00435.kb;
  real R00183(time) katal;
  extern real R00183.kf;
  extern real R00183.kb;
  real R01857(time) katal;
  extern real R01857.kf;
  extern real R01857.kb;
  real R00330(time) katal;
  extern real R00330.kf;
  extern real R00330.kb;
  real R02088(time) katal;
  extern real R02088.kf;
  extern real R02088.kb;
  real R01083(time) katal;
  extern real R01083.kf;
  extern real R01083.kb;
  real R01227(time) katal;
  extern real R01227.kf;
  extern real R01227.kb;
  real R04591(time) katal;
  extern real R04591.kf;
  extern real R04591.kb;
  real R02719(time) katal;
  extern real R02719.kf;
  extern real R02719.kb;
  real R02090(time) katal;
  extern real R02090.kf;
  extern real R02090.kb;
  real R02017(time) katal;
  extern real R02017.kf;
  extern real R02017.kb;
  real R00332(time) katal;
  extern real R00332.kf;
  extern real R00332.kb;
  real R01137(time) katal;
  extern real R01137.kf;
  extern real R01137.kb;
  real R01968(time) katal;
  extern real R01968.kf;
  extern real R01968.kb;
  real R01547(time) katal;
  extern real R01547.kf;
  extern real R01547.kb;
  real R01130(time) katal;
  extern real R01130.kf;
  extern real R01130.kb;
  real R00722(time) katal;
  extern real R00722.kf;
  extern real R00722.kb;
  real R02019(time) katal;
  extern real R02019.kf;
  extern real R02019.kb;
  real R04144(time) katal;
  extern real R04144.kf;
  extern real R04144.kb;
  real R00439(time) katal;
  extern real R00439.kf;
  extern real R00439.kb;
  real R01072(time) katal;
  extern real R01072.kf;
  extern real R01072.kb;
  real R04208(time) katal;
  extern real R04208.kf;
  extern real R04208.kb;
  real R00375(time) katal;
  extern real R00375.kf;
  extern real R00375.kb;
  real R01135(time) katal;
  extern real R01135.kf;
  extern real R01135.kb;
  real R01126(time) katal;
  extern real R01126.kf;
  extern real R01126.kb;
  real R00437(time) katal;
  extern real R00437.kf;
  extern real R00437.kb;
  real R01127(time) katal;
  extern real R01127.kf;
  extern real R01127.kb;
  real R04559(time) katal;
  extern real R04559.kf;
  extern real R04559.kb;
  real R01230(time) katal;
  extern real R01230.kf;
  extern real R01230.kb;

  // equations
  when (time=time.min) GDP = 0;
  GDP:time = (-1*R00330 + R00332 + R02019 + R00439)/uVol;
  when (time=time.min) dGDP = 0;
  dGDP:time = (-1*R01857 + R02090 + -1*R02019)/uVol;
  when (time=time.min) dGMP = 0;
  dGMP:time = (-1*R02090 + -1*R01968)/uVol;
  when (time=time.min) dIDP = 0;
  dIDP:time = (-1*R03530)/uVol;
  when (time=time.min) GTP = 0;
  GTP:time = (-1*R00441 + R00330)/uVol;
  when (time=time.min) dGTP = 0;
  dGTP:time = (-1*R00376 + R01857)/uVol;
  when (time=time.min) dITP = 0;
  dITP:time = (R03530)/uVol;
  when (time=time.min) Deoxyguanosine = 0;
  Deoxyguanosine:time = (R01968)/uVol;
  when (time=time.min) RNA = 0;
  RNA:time = (R00441 + R00435 + -1*R00439 + -1*R00437)/uVol;
  when (time=time.min) DNA = 0;
  DNA:time = (R00376 + R00375)/uVol;
  when (time=time.min) Deoxyadenosine = 0;
  Deoxyadenosine:time = (R02088)/uVol;
  when (time=time.min) ATP = 0;
  ATP:time = (R00124 + -1*R00435)/uVol;
  when (time=time.min) dATP = 0;
  dATP:time = (R01137 + -1*R00375)/uVol;
  when (time=time.min) ADP = 0;
  ADP:time = (R00127 + -1*R00124 + R02017 + R00437)/uVol;
  when (time=time.min) dADP = 0;
  dADP:time = (-1*R02017 + -1*R01137 + R01547)/uVol;
  when (time=time.min) dAMP = 0;
  dAMP:time = (-1*R02088 + -1*R01547)/uVol;
  when (time=time.min) D_minus_Ribose_space_5_minus_phosphate = 0;
  D_minus_Ribose_space_5_minus_phosphate:time = (-1*R01049)/uVol;
  when (time=time.min) space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate = 0;
  space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate:time = (R01049 + R01072)/uVol;
  when (time=time.min) L_minus_Glutamine = 0;
  L_minus_Glutamine:time = (R01072)/uVol;
  when (time=time.min) AMP = 0;
  AMP:time = (-1*R00127 + -1*R00183 + R01083)/uVol;
  when (time=time.min) Adenosine = 0;
  Adenosine:time = (R00183)/uVol;
  when (time=time.min) space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_formamido_minus_4_minus_imidazolecarboxamide = 0;
  space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_formamido_minus_4_minus_imidazolecarboxamide:time = (R04560 + -1*R01127)/uVol;
  when (time=time.min) space_5_minus_Phosphoribosylamine = 0;
  space_5_minus_Phosphoribosylamine:time = (-1*R04144 + -1*R01072)/uVol;
  when (time=time.min) N6_minus_space_1_space_2_minus_Dicarboxyethyl_space_minus_AMP = 0;
  N6_minus_space_1_space_2_minus_Dicarboxyethyl_space_minus_AMP:time = (-1*R01083 + R01135)/uVol;
  when (time=time.min) space_5_space_minus_Phosphoribosylglycinamide = 0;
  space_5_space_minus_Phosphoribosylglycinamide:time = (-1*R04325 + R04144)/uVol;
  when (time=time.min) space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxamide = 0;
  space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxamide:time = (-1*R04560 + R04559)/uVol;
  when (time=time.min) IMP = 0;
  IMP:time = (-1*R01130 + -1*R01135 + -1*R01126 + R01127)/uVol;
  when (time=time.min) Inosine = 0;
  Inosine:time = (R01126)/uVol;
  when (time=time.min) space_5_space_minus_Phosphoribosyl_minus_N_minus_formylglycinamide = 0;
  space_5_space_minus_Phosphoribosyl_minus_N_minus_formylglycinamide:time = (R04325 + -1*R04463)/uVol;
  when (time=time.min) space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_space_N_minus_succinocarboxamide_space_minus_imidazole = 0;
  space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_space_N_minus_succinocarboxamide_space_minus_imidazole:time = (R04591 + -1*R04559)/uVol;
  when (time=time.min) IDP = 0;
  IDP:time = (-1*R00722)/uVol;
  when (time=time.min) Xanthosine_space_5_space_minus_phosphate = 0;
  Xanthosine_space_5_space_minus_phosphate:time = (-1*R02719 + R01130 + -1*R01230)/uVol;
  when (time=time.min) Xanthosine = 0;
  Xanthosine:time = (R02719)/uVol;
  when (time=time.min) space_2_minus_space_Formamido_space_minus_N1_minus_space_5_space_minus_phosphoribosyl_space_acetamidine = 0;
  space_2_minus_space_Formamido_space_minus_N1_minus_space_5_space_minus_phosphoribosyl_space_acetamidine:time = (R04463 + -1*R04208)/uVol;
  when (time=time.min) ITP = 0;
  ITP:time = (R00722)/uVol;
  when (time=time.min) space_1_minus_space_5_minus_Phospho_minus_D_minus_ribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxylate = 0;
  space_1_minus_space_5_minus_Phospho_minus_D_minus_ribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxylate:time = (-1*R04209 + -1*R04591)/uVol;
  when (time=time.min) GMP = 0;
  GMP:time = (-1*R01227 + -1*R00332 + R01230)/uVol;
  when (time=time.min) Guanosine = 0;
  Guanosine:time = (R01227)/uVol;
  when (time=time.min) Aminoimidazole_space_ribotide = 0;
  Aminoimidazole_space_ribotide:time = (R04209 + R04208)/uVol;
  R04209 = R04209.kf*space_1_minus_space_5_minus_Phospho_minus_D_minus_ribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxylate - R04209.kb*Aminoimidazole_space_ribotide;
  R04325 = R04325.kf*space_5_space_minus_Phosphoribosylglycinamide - R04325.kb*space_5_space_minus_Phosphoribosyl_minus_N_minus_formylglycinamide;
  R01049 = R01049.kf*D_minus_Ribose_space_5_minus_phosphate - R01049.kb*space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate;
  R00127 = R00127.kf*AMP - R00127.kb*ADP;
  R00376 = R00376.kf*dGTP - R00376.kb*DNA;
  R00124 = R00124.kf*ADP - R00124.kb*ATP;
  R04560 = R04560.kf*space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxamide - R04560.kb*space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_formamido_minus_4_minus_imidazolecarboxamide;
  R03530 = R03530.kf*dIDP - R03530.kb*dITP;
  R04463 = R04463.kf*space_5_space_minus_Phosphoribosyl_minus_N_minus_formylglycinamide - R04463.kb*space_2_minus_space_Formamido_space_minus_N1_minus_space_5_space_minus_phosphoribosyl_space_acetamidine;
  R00441 = R00441.kf*GTP - R00441.kb*RNA;
  R00435 = R00435.kf*ATP - R00435.kb*RNA;
  R00183 = R00183.kf*AMP - R00183.kb*Adenosine;
  R01857 = R01857.kf*dGDP - R01857.kb*dGTP;
  R00330 = R00330.kf*GDP - R00330.kb*GTP;
  R02088 = R02088.kf*dAMP - R02088.kb*Deoxyadenosine;
  R01083 = R01083.kf*N6_minus_space_1_space_2_minus_Dicarboxyethyl_space_minus_AMP - R01083.kb*AMP;
  R01227 = R01227.kf*GMP - R01227.kb*Guanosine;
  R04591 = R04591.kf*space_1_minus_space_5_minus_Phospho_minus_D_minus_ribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxylate - R04591.kb*space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_space_N_minus_succinocarboxamide_space_minus_imidazole;
  R02719 = R02719.kf*Xanthosine_space_5_space_minus_phosphate - R02719.kb*Xanthosine;
  R02090 = R02090.kf*dGMP - R02090.kb*dGDP;
  R02017 = R02017.kf*dADP - R02017.kb*ADP;
  R00332 = R00332.kf*GMP - R00332.kb*GDP;
  R01137 = R01137.kf*dADP - R01137.kb*dATP;
  R01968 = R01968.kf*dGMP - R01968.kb*Deoxyguanosine;
  R01547 = R01547.kf*dAMP - R01547.kb*dADP;
  R01130 = R01130.kf*IMP - R01130.kb*Xanthosine_space_5_space_minus_phosphate;
  R00722 = R00722.kf*IDP - R00722.kb*ITP;
  R02019 = R02019.kf*dGDP - R02019.kb*GDP;
  R04144 = R04144.kf*space_5_minus_Phosphoribosylamine - R04144.kb*space_5_space_minus_Phosphoribosylglycinamide;
  R00439 = R00439.kf*RNA - R00439.kb*GDP;
  R01072 = R01072.kf*space_5_minus_Phosphoribosylamine - R01072.kb*space_5_minus_Phospho_minus_alpha_minus_D_minus_ribose_space_1_minus_diphosphate*L_minus_Glutamine;
  R04208 = R04208.kf*space_2_minus_space_Formamido_space_minus_N1_minus_space_5_space_minus_phosphoribosyl_space_acetamidine - R04208.kb*Aminoimidazole_space_ribotide;
  R00375 = R00375.kf*dATP - R00375.kb*DNA;
  R01135 = R01135.kf*IMP - R01135.kb*N6_minus_space_1_space_2_minus_Dicarboxyethyl_space_minus_AMP;
  R01126 = R01126.kf*IMP - R01126.kb*Inosine;
  R00437 = R00437.kf*RNA - R00437.kb*ADP;
  R01127 = R01127.kf*space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_formamido_minus_4_minus_imidazolecarboxamide - R01127.kb*IMP;
  R04559 = R04559.kf*space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_space_N_minus_succinocarboxamide_space_minus_imidazole - R04559.kb*space_1_minus_space_5_space_minus_Phosphoribosyl_space_minus_5_minus_amino_minus_4_minus_imidazolecarboxamide;
  R01230 = R01230.kf*Xanthosine_space_5_space_minus_phosphate - R01230.kb*GMP;

  // variable properties
  default.sbmlRole="compartment";
  uVol.sbmlRole="compartment";
  E2_space_7_space_4_space_8.sbmlRole="species";
  E2_space_7_space_4_space_8.sbmlCompartment="uVol";
  E1_space_17_space_4_space_1.sbmlRole="species";
  E1_space_17_space_4_space_1.sbmlCompartment="uVol";
  E2_space_7_space_4_space_6.sbmlRole="species";
  E2_space_7_space_4_space_6.sbmlCompartment="uVol";
  E3_space_1_space_3_space_5.sbmlRole="species";
  E3_space_1_space_3_space_5.sbmlCompartment="uVol";
  E2_space_7_space_7_space_7.sbmlRole="species";
  E2_space_7_space_7_space_7.sbmlCompartment="uVol";
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