// This model generated automatically from SBML
// WARNING: Renamed variable _space_S_space__minus_Malate to xxx_space_S_space__minus_Malate due to JSim namespace restrictions
// WARNING: Renamed variable _space_2_minus_Oxoglutarate to xxx_space_2_minus_Oxoglutarate due to JSim namespace restrictions

// unit definitions
import nsrunit;
unit conversion off;

// SBML property definitions
property sbmlRole=string;
property sbmlName=string;
property sbmlCompartment=string;

// SBML reactions
// R00405: Succinate => Succinyl_minus_CoA 
// R01899: Isocitrate => Oxalosuccinate 
// R01082: _space_S_space__minus_Malate => Fumarate 
// R00351: Citrate CoA <=> Acetyl_minus_CoA Oxaloacetate 
// R01324: Citrate => Isocitrate 
// R07618: Enzyme_space_N6_minus__space_dihydrolipoyl_space_lysine => Enzyme_space_N6_minus__space_lipoyl_space_lysine 
// R00344: Pyruvate => Oxaloacetate 
// R00268: Oxalosuccinate => _space_2_minus_Oxoglutarate CO2 
// R02164: Succinate => Fumarate 
// R01325: Citrate => cis_minus_Aconitate 
// R00431: Oxaloacetate => Phosphoenolpyruvate 
// R01900: cis_minus_Aconitate => Isocitrate 
// R00412: Succinate => Fumarate 
// R00362: Citrate => Acetate Oxaloacetate 

math main {
  realDomain time second;
  time.min=0;
  extern time.max;
  extern time.delta;

  // variable definitions
  real default = 1 L;
  real uVol = 1 L;
  real E1_space_3_space_99_space_1 = 0 M;
  real E4_space_2_space_1_space_2 = 0 M;
  real E1_space_3_space_5_space_1 = 0 M;
  real E6_space_2_space_1_space_5 = 0 M;
  real E4_space_1_space_1_space_32 = 0 M;
  real E6_space_4_space_1_space_1 = 0 M;
  real E2_space_3_space_3_space_1 = 0 M;
  real E1_space_8_space_1_space_4 = 0 M;
  real E4_space_1_space_3_space_6 = 0 M;
  real E4_space_2_space_1_space_3 = 0 M;
  real E1_space_1_space_1_space_42 = 0 M;
  real Succinate(time) M;
  real xxx_space_S_space__minus_Malate(time) M;
  real Fumarate(time) M;
  real Oxaloacetate(time) M;
  real Succinyl_minus_CoA(time) M;
  real Acetyl_minus_CoA(time) M;
  real Enzyme_space_N6_minus__space_dihydrolipoyl_space_lysine(time) M;
  real Phosphoenolpyruvate(time) M;
  real Pyruvate(time) M;
  real CoA(time) M;
  real Citrate(time) M;
  real Enzyme_space_N6_minus__space_lipoyl_space_lysine(time) M;
  real Acetate(time) M;
  real cis_minus_Aconitate(time) M;
  real Isocitrate(time) M;
  real Oxalosuccinate(time) M;
  real xxx_space_2_minus_Oxoglutarate(time) M;
  real CO2(time) M;
  real R00405(time) katal;
  extern real R00405.kf;
  extern real R00405.kb;
  real R01899(time) katal;
  extern real R01899.kf;
  extern real R01899.kb;
  real R01082(time) katal;
  extern real R01082.kf;
  extern real R01082.kb;
  real R00351(time) katal;
  extern real R00351.kf;
  extern real R00351.kb;
  real R01324(time) katal;
  extern real R01324.kf;
  extern real R01324.kb;
  real R07618(time) katal;
  extern real R07618.kf;
  extern real R07618.kb;
  real R00344(time) katal;
  extern real R00344.kf;
  extern real R00344.kb;
  real R00268(time) katal;
  extern real R00268.kf;
  extern real R00268.kb;
  real R02164(time) katal;
  extern real R02164.kf;
  extern real R02164.kb;
  real R01325(time) katal;
  extern real R01325.kf;
  extern real R01325.kb;
  real R00431(time) katal;
  extern real R00431.kf;
  extern real R00431.kb;
  real R01900(time) katal;
  extern real R01900.kf;
  extern real R01900.kb;
  real R00412(time) katal;
  extern real R00412.kf;
  extern real R00412.kb;
  real R00362(time) katal;
  extern real R00362.kf;
  extern real R00362.kb;

  // equations
  when (time=time.min) Succinate = 0;
  (Succinate*uVol):time = -1*R00405 + -1*R02164 + -1*R00412;
  when (time=time.min) xxx_space_S_space__minus_Malate = 0;
  (xxx_space_S_space__minus_Malate*uVol):time = -1*R01082;
  when (time=time.min) Fumarate = 0;
  (Fumarate*uVol):time = R01082 + R02164 + R00412;
  when (time=time.min) Oxaloacetate = 0;
  (Oxaloacetate*uVol):time = R00351 + R00344 + -1*R00431 + R00362;
  when (time=time.min) Succinyl_minus_CoA = 0;
  (Succinyl_minus_CoA*uVol):time = R00405;
  when (time=time.min) Acetyl_minus_CoA = 0;
  (Acetyl_minus_CoA*uVol):time = R00351;
  when (time=time.min) Enzyme_space_N6_minus__space_dihydrolipoyl_space_lysine = 0;
  (Enzyme_space_N6_minus__space_dihydrolipoyl_space_lysine*uVol):time = -1*R07618;
  when (time=time.min) Phosphoenolpyruvate = 0;
  (Phosphoenolpyruvate*uVol):time = R00431;
  when (time=time.min) Pyruvate = 0;
  (Pyruvate*uVol):time = -1*R00344;
  when (time=time.min) CoA = 0;
  (CoA*uVol):time = -1*R00351;
  when (time=time.min) Citrate = 0;
  (Citrate*uVol):time = -1*R00351 + -1*R01324 + -1*R01325 + -1*R00362;
  when (time=time.min) Enzyme_space_N6_minus__space_lipoyl_space_lysine = 0;
  (Enzyme_space_N6_minus__space_lipoyl_space_lysine*uVol):time = R07618;
  when (time=time.min) Acetate = 0;
  (Acetate*uVol):time = R00362;
  when (time=time.min) cis_minus_Aconitate = 0;
  (cis_minus_Aconitate*uVol):time = R01325 + -1*R01900;
  when (time=time.min) Isocitrate = 0;
  (Isocitrate*uVol):time = -1*R01899 + R01324 + R01900;
  when (time=time.min) Oxalosuccinate = 0;
  (Oxalosuccinate*uVol):time = R01899 + -1*R00268;
  when (time=time.min) xxx_space_2_minus_Oxoglutarate = 0;
  (xxx_space_2_minus_Oxoglutarate*uVol):time = R00268;
  when (time=time.min) CO2 = 0;
  (CO2*uVol):time = R00268;
  R00405 = R00405.kf*Succinate - R00405.kb*Succinyl_minus_CoA;
  R01899 = R01899.kf*Isocitrate - R01899.kb*Oxalosuccinate;
  R01082 = R01082.kf*_space_S_space__minus_Malate - R01082.kb*Fumarate;
  R00351 = R00351.kf*Citrate*CoA - R00351.kb*Acetyl_minus_CoA*Oxaloacetate;
  R01324 = R01324.kf*Citrate - R01324.kb*Isocitrate;
  R07618 = R07618.kf*Enzyme_space_N6_minus__space_dihydrolipoyl_space_lysine - R07618.kb*Enzyme_space_N6_minus__space_lipoyl_space_lysine;
  R00344 = R00344.kf*Pyruvate - R00344.kb*Oxaloacetate;
  R00268 = R00268.kf*Oxalosuccinate - R00268.kb*_space_2_minus_Oxoglutarate*CO2;
  R02164 = R02164.kf*Succinate - R02164.kb*Fumarate;
  R01325 = R01325.kf*Citrate - R01325.kb*cis_minus_Aconitate;
  R00431 = R00431.kf*Oxaloacetate - R00431.kb*Phosphoenolpyruvate;
  R01900 = R01900.kf*cis_minus_Aconitate - R01900.kb*Isocitrate;
  R00412 = R00412.kf*Succinate - R00412.kb*Fumarate;
  R00362 = R00362.kf*Citrate - R00362.kb*Acetate*Oxaloacetate;

  // variable properties
  default.sbmlRole="compartment";
  uVol.sbmlRole="compartment";
  E1_space_3_space_99_space_1.sbmlRole="species";
  E1_space_3_space_99_space_1.sbmlCompartment="uVol";
  E4_space_2_space_1_space_2.sbmlRole="species";
  E4_space_2_space_1_space_2.sbmlCompartment="uVol";
  E1_space_3_space_5_space_1.sbmlRole="species";
  E1_space_3_space_5_space_1.sbmlCompartment="uVol";
  E6_space_2_space_1_space_5.sbmlRole="species";
  E6_space_2_space_1_space_5.sbmlCompartment="uVol";
  E4_space_1_space_1_space_32.sbmlRole="species";
  E4_space_1_space_1_space_32.sbmlCompartment="uVol";
  E6_space_4_space_1_space_1.sbmlRole="species";
  E6_space_4_space_1_space_1.sbmlCompartment="uVol";
  E2_space_3_space_3_space_1.sbmlRole="species";
  E2_space_3_space_3_space_1.sbmlCompartment="uVol";
  E1_space_8_space_1_space_4.sbmlRole="species";
  E1_space_8_space_1_space_4.sbmlCompartment="uVol";
  E4_space_1_space_3_space_6.sbmlRole="species";
  E4_space_1_space_3_space_6.sbmlCompartment="uVol";
  E4_space_2_space_1_space_3.sbmlRole="species";
  E4_space_2_space_1_space_3.sbmlCompartment="uVol";
  E1_space_1_space_1_space_42.sbmlRole="species";
  E1_space_1_space_1_space_42.sbmlCompartment="uVol";
  Succinate.sbmlRole="species";
  Succinate.sbmlCompartment="uVol";
  xxx_space_S_space__minus_Malate.sbmlRole="species";
  xxx_space_S_space__minus_Malate.sbmlName="_space_S_space__minus_Malate";
  xxx_space_S_space__minus_Malate.sbmlCompartment="uVol";
  Fumarate.sbmlRole="species";
  Fumarate.sbmlCompartment="uVol";
  Oxaloacetate.sbmlRole="species";
  Oxaloacetate.sbmlCompartment="uVol";
  Succinyl_minus_CoA.sbmlRole="species";
  Succinyl_minus_CoA.sbmlCompartment="uVol";
  Acetyl_minus_CoA.sbmlRole="species";
  Acetyl_minus_CoA.sbmlCompartment="uVol";
  Enzyme_space_N6_minus__space_dihydrolipoyl_space_lysine.sbmlRole="species";
  Enzyme_space_N6_minus__space_dihydrolipoyl_space_lysine.sbmlCompartment="uVol";
  Phosphoenolpyruvate.sbmlRole="species";
  Phosphoenolpyruvate.sbmlCompartment="uVol";
  Pyruvate.sbmlRole="species";
  Pyruvate.sbmlCompartment="uVol";
  CoA.sbmlRole="species";
  CoA.sbmlCompartment="uVol";
  Citrate.sbmlRole="species";
  Citrate.sbmlCompartment="uVol";
  Enzyme_space_N6_minus__space_lipoyl_space_lysine.sbmlRole="species";
  Enzyme_space_N6_minus__space_lipoyl_space_lysine.sbmlCompartment="uVol";
  Acetate.sbmlRole="species";
  Acetate.sbmlCompartment="uVol";
  cis_minus_Aconitate.sbmlRole="species";
  cis_minus_Aconitate.sbmlCompartment="uVol";
  Isocitrate.sbmlRole="species";
  Isocitrate.sbmlCompartment="uVol";
  Oxalosuccinate.sbmlRole="species";
  Oxalosuccinate.sbmlCompartment="uVol";
  xxx_space_2_minus_Oxoglutarate.sbmlRole="species";
  xxx_space_2_minus_Oxoglutarate.sbmlName="_space_2_minus_Oxoglutarate";
  xxx_space_2_minus_Oxoglutarate.sbmlCompartment="uVol";
  CO2.sbmlRole="species";
  CO2.sbmlCompartment="uVol";
  R00405.sbmlRole="rate";
  R00405.kf.sbmlRole="rate";
  R00405.kb.sbmlRole="rate";
  R01899.sbmlRole="rate";
  R01899.kf.sbmlRole="rate";
  R01899.kb.sbmlRole="rate";
  R01082.sbmlRole="rate";
  R01082.kf.sbmlRole="rate";
  R01082.kb.sbmlRole="rate";
  R00351.sbmlRole="rate";
  R00351.kf.sbmlRole="rate";
  R00351.kb.sbmlRole="rate";
  R01324.sbmlRole="rate";
  R01324.kf.sbmlRole="rate";
  R01324.kb.sbmlRole="rate";
  R07618.sbmlRole="rate";
  R07618.kf.sbmlRole="rate";
  R07618.kb.sbmlRole="rate";
  R00344.sbmlRole="rate";
  R00344.kf.sbmlRole="rate";
  R00344.kb.sbmlRole="rate";
  R00268.sbmlRole="rate";
  R00268.kf.sbmlRole="rate";
  R00268.kb.sbmlRole="rate";
  R02164.sbmlRole="rate";
  R02164.kf.sbmlRole="rate";
  R02164.kb.sbmlRole="rate";
  R01325.sbmlRole="rate";
  R01325.kf.sbmlRole="rate";
  R01325.kb.sbmlRole="rate";
  R00431.sbmlRole="rate";
  R00431.kf.sbmlRole="rate";
  R00431.kb.sbmlRole="rate";
  R01900.sbmlRole="rate";
  R01900.kf.sbmlRole="rate";
  R01900.kb.sbmlRole="rate";
  R00412.sbmlRole="rate";
  R00412.kf.sbmlRole="rate";
  R00412.kb.sbmlRole="rate";
  R00362.sbmlRole="rate";
  R00362.kf.sbmlRole="rate";
  R00362.kb.sbmlRole="rate";
}