Capillary-tissue unit using serial stirred tanks with passive exchange via both a passive linear and a saturable transporter
Model number: 0264
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N well stirred tanks (i.e. compartmental models with flow) representing the capillary region are connected in series and exchange with N stagnant tanks in parallel representing the extravascular region. The exchange is via both a passive linear and a saturable Michaelis-Menten transporter.
The equations for this model may be viewed by running the JSim model applet and clicking on the Source tab at the bottom left of JSim's Run Time graphical user interface. The equations are written in JSim's Mathematical Modeling Language (MML). See the Introduction to MML and the MML Reference Manual. Additional documentation for MML can be found by using the search option at the Physiome home page.
Schwartz L.M, Bukowski T.R, Ploger J.D, Bassingthwaighte J.B., Endothelial adenosine transporter characterization in perfused guinea pig hearts. Am. J. Physiol. Heart Circ. Physiol. 279, H1502-H1511, 2000.
CTEX20 models:CTEX20: Basic CTEX20 Model
CTEX20b: Additional extravascular exchange with Michaelis-Menten transporter
CTEX20c: Additional extravascular exchange with adenosine and inosine competing for saturable Michaelis-Menten transporter. Includes CTEX10 for reference intravascular solute (albumin)
See also:BTEX20: Distributed 2 region PDE model
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[This page was last modified 02Nov16, 2:28 pm.]
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