Four-compartment whole body model with recirculation: repeated injections and first order hepatic clearance of Indocyanine Green dye.
Model number: 0103
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Figure: Time course of ICG clearance during multiple injections of ICG over the course of 240 minutes.
Green line is model simulation results, triangles are Edwards 1960 figure 1 data, and black lines
are injections of ICG (for timing purposes only).
The equations for this model may be viewed by running the JSim model applet and clicking on the Source tab at the bottom left of JSim's Run Time graphical user interface. The equations are written in JSim's Mathematical Modeling Language (MML). See the Introduction to MML and the MML Reference Manual. Additional documentation for MML can be found by using the search option at the Physiome home page.
- Edwards AWT, Bassingthwaighte JB, Sutterer WF, and Wood EH. Blood level of indocyanine green in the dog during multiple dye curves and its effect on instrumental calibration. Proc S M Mayo Clin 35: 747-751, 1960.
- Edwards AWT, Isaacson J, Sutterer WF, Bassingthwaighte JB, and Wood EH. Indocyanine green densitometry in flowing blood compensated for background dye. J Appl Physiol 18: 1294-1304, 1963.
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Posted by: BEJ
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[This page was last modified 02Nov16, 2:27 pm.]
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