Compliant_bifurcating_bronchiole_compliant_alveoli

This model represents a bifurcating compliant bronchiole with two compliant alveoli.

Model number: 0124

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Description

  This model represents a bifurcating compliant bronchiole with two compliant alveoli.
  The resistance offered by bronchial wall to the flow of air is represented by the resistor 
  in the electrical circuit. The compliance of the bronchiole is represented by the capacitor.
  All three bronchi have separate compliances which are represented by three individual 
  capacitors. The alveolar sac compliance is repsented by a capcitor. The alveolar sac changes 
  its volume as a function of inlet flow or pressure.

The equations for this model may be viewed by running the JSim model applet and clicking on the Source tab at the bottom left of JSim's Run Time graphical user interface. The equations are written in JSim's Mathematical Modeling Language (MML). See the Introduction to MML and the MML Reference Manual. Additional documentation for MML can be found by using the search option at the Physiome home page.

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References

   K. R. Lutchen and G. M. Saidel, Estimation of mechanical parameters in multicompartment 
   models applied to normal and obstructed lungs during tidal breathing, 
   IEEE Trans. Biomed. Eng., vol. BME-33, no. 9, pp. 878-887, Sept. 1986.

   Biomechanics by Y.C. Fung (Text Book)

Related Models

Key Terms

Compliant bronchiole, Compliant alveoli, Compliant alveolus, Bronchiole, Alveolus, Respiratory system, respiratory mechanics, airway

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Posted by: BEJ

Acknowledgements

Please cite www.physiome.org in any publication for which this software is used and send an email with the citation and, if possible, a PDF file of the paper to: staff@physiome.org.
Or send a copy to:
The National Simulation Resource, Director J. B. Bassingthwaighte, Department of Bioengineering, University of Washington, Seattle WA 98195-5061.

[This page was last modified 07Jun11, 9:39 am.]

Model development and archiving support at physiome.org provided by the following grants: NIH/NIBIB BE08407 Software Integration, JSim and SBW 6/1/09-5/31/13; NIH/NHLBI T15 HL88516-01 Modeling for Heart, Lung and Blood: From Cell to Organ, 4/1/07-3/31/11; NSF BES-0506477 Adaptive Multi-Scale Model Simulation, 8/15/05-7/31/08; NIH/NHLBI R01 HL073598 Core 3: 3D Imaging and Computer Modeling of the Respiratory Tract, 9/1/04-8/31/09; as well as prior support from NIH/NCRR P41 RR01243 Simulation Resource in Circulatory Mass Transport and Exchange, 12/1/1980-11/30/01 and NIH/NIBIB R01 EB001973 JSim: A Simulation Analysis Platform, 3/1/02-2/28/07.