The autoregulatory device (ARD) developed by Gao et al. is reproduced here to simulate the autoregulation of cerebral blood flow in the 300 to 50 micron diameter vessels.
Code: Download the JSim project file.
Key Terms: Autoregulation, Cardiovascular System, Cerbral Blood Flow, Vascular Resistance, Microvasculature, Regulatory Response
Brian Carlson carlsonb@u.washington.edu
Model development and archiving support at physiome.org provided by the following grants: NIH/NHLBI T15 HL88516-01 Modeling for Heart, Lung and Blood: From Cell to Organ, 4/1/07-3/31/11; NSF BES-0506477 Adaptive Multi-Scale Model Simulation, 8/15/05-7/31/08; NIH/NHLBI R01 HL073598 Core 3: 3D Imaging and Computer Modeling of the Respiratory Tract, 9/1/04-8/31/09; as well as prior support from NIH/NCRR P41 RR01243 Simulation Resource in Circulatory Mass Transport and Exchange, 12/1/1980-11/30/01 and NIH/NIBIB R01 EB001973 JSim: A Simulation Analysis Platform, 3/1/02-2/28/07.