Cardiac Physiome Society 6-9 Nov. 2017 Toronto, Canada

Next Cardiac Physiome Society Workshop: Looking Forward

The next Cardiac Physiome Society meeting is scheduled in Spring 2019. Please direct questions to Tammo Delhaas at Maastricht Univ. in the Netherlands.

Inquiries about the 2017 Workshop can be directed to Jim Bassingthwaighte at University of Washington, in Seattle.

Cardiac Physiome Society's 20th Workshop: Metabolism, Mechanics and Excitation

The Cardiac Physiome Society's annual meeting was be held at the University of Toronto, Canada from Nov. 6th to Nov 9th, 2017. Opening reception was at the Chelsea Hotel from 6:30 to 8:00 pm on Nov. 6th.

Main meeting: The central theme, building on the past emphasis on electrophysiology and mechanics, is on linking these to metabolism. The overt goal is to foster bridging “silos of knowledge” into conciliated structured knowledge linking metabolism, signaling, electrophysiology and mechanics, via mathematical models. Topics include:

  • Metabolic changes due to changes in electrophysiology and mechanics.
  • Quantitative analysis in tissue engineering, growth processes, and signaling, including substrate influences, and substrate-specific receptors, e.g. FFAR1-5.
  • Analyzing experimental findings via models of metabolism, excitation and contraction in health, exercise, hypertrophy and failure.
  • Examining metabolic shifts, transcription regulation with remodeling, amino acid and protein metabolism, inflammatory responses.
  • Training strategies in development and use of models in experiment design and analysis.
  • Demonstrations of reproducible modeling for dissemination and archiving and applications of modeling in clinical diagnosis and therapy.

A tutorial / technical session (Thursday AM Nov 9th), is on computational methods modeling principles and practice simulation platforms, reproducibility.


Thursday 1:00-6:00 PM: CiPA (Comprehensive in-vitro Pro-arrhythmia Assay), an international initiative, launched in 2013 by the US Food and Drug Administration, other drug regulatory agencies, industry and academic collaborators, to develop and validate a new mechanistic, in vitro and in silico paradigm for evaluating the proarrhythmic risk of new drugs. CiPA studies include ion channel effects in cell lines combined with mathematical action potential modelling to predict the effect of multiple ion channel block and associated pro-arrhythmic risk, and to check the integrated effect with stem-cell derived cardiomyocyte measurements. The CiPA project website is

Important Dates

May 15, 2017 Registration Opens
May 15, 2017 Abstract Submissions Begin
Sept. 28, 2017 Deadline: Abstracts for 10 minute Presentation Selection
Oct 1, 2017 Notification for 10 minute Presentation speakers
Oct. 10, 2017 . Latest date to get discount rate at Chelsea Hotel
Oct. 16, 2017 Abstract Submissions Closed
Oct. 31, 2017 Registration Cancellation and Refunds End
Nov. 6, 2017 Evening Reception (Chelsea Hotel Gerrard Room)6:30-8:00 PM
Nov. 7 & 8, 2017 xxxxx.
Main meeting & posters-U of T Faculty Club 41 Wilcocks St.

Nov. 9, 2017 8:30 am Toronto General Hospital (Room 025/026) -- Tutorial session
Nov. 9, 2017 12:15 pm Lunch in the MaRS Building at the TBEP lounge
Nov. 9, 2017 1:00 pm Toronto General Hospital (Room 025/026) -- CiPA session


Sponsor opportunities are currently available. Please email inquiries or questions to


A PDF of the invitation is available. Click here to initiate the download.