JSim CellML Models Page
This page allows users to run models from the CellML model archive under JSim. To run these models online, you must have Java installed on your computer. To run them in JSim on your own computer, download the model code and the JSim application. Either way, see Running JSim for instructions on how to use JSim. Since CellML models do not specify simulation time length or delta, these must be set by the user before running the model.
Users are strongly advised to read Running CellML Models under JSim before running CellML models under JSim.
Currently available models
- Number of CellML v1.0 models in the archive: 910
- Number of those models runnable under JSim: 840
- Number of those models passing unit balance: 698
- Models not passing unit balance are indicated by
adrian_chandler_hodgkin_1970
Voltage clamp experiments in striated muscle fibres
- adrian_chandler_hodgkin_1970: View MML
(Java required)
aguda_b_1999
A quantitative analysis of the kinetics of the G2 DNA damage checkpoint system
- aguda_b_1999: View MML (Java required)
aguda_tang_1999
The kinetic origins of the restriction point in the mammalian cell cycle
- aguda_tang_1999: View MML (Java required)
albert_haanstra_hannaert_vanroy_opperdoes_bakker_michels_2005
- albert_2005: View MML (Java required)
albrecht_colegrove_friel_2002
Differential Regulation of ER Ca2+ Uptake and Release Rates Accounts for Multiple Modes of Ca2+-induced Ca2+ Release
- albrecht_colegrove_friel_2002: View MML
(Java required)
albrecht_colegrove_hongpaisan_pivovarova_andrews_friel_2001
Multiple Modes of Calcium-induced Calcium Release in Sympathetic Neurons I: Attenuation of Endoplasmic Reticulum Ca2+ Accumulation at Low [Ca2+]i during Weak Depolarisation
- albrecht_colegrove_hongpaisan_pivovarova_andrews_friel_2001: View MML (Java required)
alexander_wahl_2010
Self-tolerance and Autoimmunity in a Regulatory T Cell Model
- alexander_2010: View MML (Java required)
- alexander_2010_system2: View MML (Java required)
- alexander_2010_system3: View MML (Java required)
- alexander_2010_system4: View MML (Java required)
aon_cortassa_2002
Coherent and robust modulation of a metabolic network by cytoskeletal organization and dynamics
- aon_cortassa_2002: View MML (Java required)
aslanidi_atrial_model_2009
Mechanisms of transition from normal to reentrant electrical activity in a model of rabbit atrial tissue: interaction of tissue heterogeneity and anisotropy
- aslanidi_atrial_model_2009_LindbladCa_corrected: View MML (Java required)
aslanidi_purkinje_model_2009
Optimal velocity and safety of discontinuous conduction through the heterogeneous Purkinje-ventricular junction
- aslanidi_2009: View MML (Java required)
asthagiri_lauffenburger_2001
A Compuational Study of Feedback Effects on Signal Dynamics in a Mitogen-Activated Protein Kinase (MAPK) Pathway Model
- asthagiri_lauffenburger_2001: View MML
(Java required)
bagci_2006
Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores
- bagci_2006: View MML (Java required)
bagci_2008
Computational insights on the competing effects of nitric oxide in regulating apoptosis
- bagci_2008a: View MML (Java required)
- bagci_2008b: View MML (Java required)
bakker_mensonides_teusink_vanhoek_michels_westerhoff_2000
Compartmentation protects trypanosomes from the dangerous design of glycolysis
- bakker_mensonides_teusink_vanhoek_michels_westerhoff_2000: View MML (Java required)
bakker_michels_opperdoes_westerhoff_1997
Glycolysis in Bloodstream Form Trypanosoma brucei Can Be Understood in Terms of the Kinetics of the Glycolytic Enzymes
- bakker_michels_opperdoes_westerhoff_1997: View MML (Java required)
barberis_klipp_vanoni_alberghina_2007
Cell Size at S Phase Initiation: An Emergent Property of the G1/S Network
- barberis_klipp_vanoni_alberghina_2007: View MML (Java required)
baylor_hollingworth_chandler_2002
Comparison of Simulated and Measured Calcium Sparks in Intact Skeletal Muscle Fibers of the Frog
- baylor_hollingworth_chandler_2002_a: View MML (Java required)
- baylor_hollingworth_chandler_2002_b: View MML (Java required)
- baylor_hollingworth_chandler_2002_c: View MML (Java required)
- baylor_hollingworth_chandler_2002_d: View MML (Java required)
- baylor_hollingworth_chandler_2002_e: View MML (Java required)
- baylor_hollingworth_chandler_2002_f: View MML (Java required)
beard_2005
A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation
- beard_2005: View MML (Java required)
beeler_reuter_1977
Reconstruction of the action potential of ventricular myocardial fibres
- beeler_reuter_1977: View MML (Java required)
benson_2008
The canine virtual ventricular wall: a platform for dissecting pharmacological effects on propagation and arrhythmogenesis
- benson_endocardial_2008: View MML (Java required)
- benson_epicardial_2008: View MML (Java required)
- benson_mcell_2008: View MML (Java required)
bental_2006
Simplified models for gas exchange in the human lungs
- bental_2006: View MML (Java required)
bernus_wilders_zemlin_verschelde_panfilov_2002
A computationally efficient electrophysiological model of human ventricular cells
- bernus_wilders_zemlin_verschelde_panfilov_2002: No JSim version is currently available. (View error log)
bertram_arnot_zamponi_2002
Role for G protein G-beta-gamma isoform specificity in synaptic signal processing: a computational study
- bertram_arnot_zamponi_2002: View MML (Java required)
- bertram_arnot_zamponi_2002_post: View MML (Java required)
bertram_previte_sherman_kinard_satin_2000
The Phantom Burster Model for Pancreatic Beta Cells
- bertram_previte_sherman_kinard_satin_2000_fast: View MML (Java required)
- bertram_previte_sherman_kinard_satin_2000_medium: View MML (Java required)
- bertram_previte_sherman_kinard_satin_2000_slow: View MML (Java required)
bertram_rhoads_cimbora_2008
A phantom bursting mechanism for episodic bursting
- bertram_2008: View MML
(Java required)
- bertram_2008_noisy: View MML
(Java required)
bertram_satin_pedersen_luciani_sherman_2007
Intra- and inter-islet synchronization of metabolically driven insulin secretion
- bertram_satin_pedersen_luciani_sherman_2007: View MML (Java required)
bertram_satin_zhang_smolen_sherman_2004
Calcium and Glycolysis Mediate Multiple Bursting Modes in Pancreatic Islets
- bertram_satin_zhang_smolen_sherman_2004_a: View MML (Java required)
- bertram_satin_zhang_smolen_sherman_2004_b: View MML (Java required)
bertram_sherman_2004
A Calcium-based Phantom Bursting Model for Pancreatic Islets
- bertram_sherman_2004: View MML (Java required)
bertram_smolen_sherman_mears_atwater_martin_soria_1995
A role for calcium release-activated current (CRAC) in cholinergic modulation of electrical activity in pancreatic beta-cells
- bertram_smolen_sherman_mears_atwater_martin_soria_1995: View MML (Java required)
bhalla_iyengar_1999
Emergent Properties of Networks of Biological Signaling Pathways
- bhalla_iyengar_1999_a: View MML
(Java required)
- bhalla_iyengar_1999_b: View MML
(Java required)
- bhalla_iyengar_1999_c: View MML
(Java required)
- bhalla_iyengar_1999_d: View MML
(Java required)
- bhalla_iyengar_1999_e: View MML
(Java required)
- bhalla_iyengar_1999_f: View MML
(Java required)
- bhalla_iyengar_1999_g: View MML
(Java required)
- bhalla_iyengar_1999_h: View MML
(Java required)
- bhalla_iyengar_1999_i: View MML
(Java required)
- bhalla_iyengar_1999_j: No JSim version is currently available. (View error log)
bindschadler_sneyd_2001
A Bifurcation Analysis of Two Coupled Calcium Oscillators
- bindschadler_sneyd_2001: View MML (Java required)
bingzheng_zhenye_liansong_1990
A mathematical model of the regulation system of the secretion of glucocorticoids
- bingzheng_zhenye_liansong_1990: View MML (Java required)
bondarenko_szigeti_bett_kim_rasmusson_2004
Computer model of action potential of mouse ventricular myocytes
- bondarenko_szigeti_bett_kim_rasmusson_2004_apical: View MML (Java required)
- bondarenko_szigeti_bett_kim_rasmusson_2004_septal: View MML (Java required)
bonhoeffer_rembiszewski_ortiz_nixon_2000
Risks and benefits of structured antiretroviral drug therapy interruptions in HIV-1 infection
- bonhoeffer_rembiszewski_ortiz_nixon_2000_a: View MML (Java required)
- bonhoeffer_rembiszewski_ortiz_nixon_2000_b: View MML (Java required)
- bonhoeffer_rembiszewski_ortiz_nixon_2000_c: View MML (Java required)
borghans_1997
Complex intracellular calcium oscillations. A theoretical exploration of possible mechanisms
- borghans_dupont_goldbeter_1997a: View MML (Java required)
- borghans_dupont_goldbeter_1997b: View MML (Java required)
- borghans_dupont_goldbeter_1997c: View MML (Java required)
bornheimer_maurya_farquhar_subramaniam_2004
Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction
- bornheimer_2004: View MML (Java required)
boyett_zhang_garny_holden_2001
Control of the pacemaker activity of the sinoatrial node by intracellular Ca2+. Experiments and modelling
- boyett_zhang_garny_holden_2001: View MML (Java required)
brightman_fell_2000
Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells.
- brightman_fell_2000: View MML (Java required)
brown_choe_shanahan_czeisler_1997
A mathematical model of diurnal variations in human plasma melatonin levels
- brown_choe_shanahan_czeisler_1997: View MML (Java required)
bueno_2007
Mathematical modeling and spectral simulation of genetic diseases in the human heart
- bueno_2007: View MML (Java required)
butera_rinzel_smith_1999
Models of Respiratory Rhythm Generation in the Pre-Botzinger Complex. I. Bursting Pacemaker Neurons
- butera_rinzel_smith_1999: View MML (Java required)
- butera_rinzel_smith_1999_model2: View MML (Java required)
- butera_single_cell_1999: View MML (Java required)
- butera_ten_cell_1999: View MML (Java required)
calzone_thieffry_tyson_novak_2007
Dynamical modeling of syncytial mitotic cycles in Drosophila embryos
- calzone_thieffry_tyson_novak_2007: View MML (Java required)
campbell_chandra_2006
Functions of Stretch Activation in Heart Muscle
- campbell_chandra_2006: View MML (Java required)
cartwright_husain_1986
A model for the control of testosterone secretion
- cartwright_husain_1986: View MML (Java required)
chang_fujita_1999
A kinetic model of the thiazide-sensitive Na-Cl cotransporter
- chang_fujita_1999: View MML (Java required)
chang_fujita_2001
A numerical model of acid-base transport in rat distal tubule
- chang_fujita_2001_H_ATPase: View MML (Java required)
- chang_fujita_2001_Na_H_exchanger: View MML (Java required)
- chang_fujita_2001_anion_exchanger: View MML (Java required)
chang_fujita_b_1999
A numerical model of the renal distal tubule
- chang_fujita_b_1999: View MML
(Java required)
chassagnole_rais_quentin_fell_mazat_2001
An integrated study of Threonine-pathway enzyme kinetics in Escherichia coli
- chassagnole_rais_quentin_fell_mazat_2001: View MML (Java required)
chauhan_legewie_westermark_lorenzen_herzel_2008
- chauhan_2008: View MML
(Java required)
chay_1997
Effects of extracellular calcium on electrical bursting and intracellular and luminal calcium oscillations in insulin secreting pancreatic beta-cells
- chay_1997: View MML (Java required)
chay_lee_fan_1995
Appearance of Phase-locked Wenchbach-like Rhythms, Devil's Staircase and Universality in Intracellular Calcium Spikes in Non-excitable Cell Models
- chay_lee_fan_1995: View MML
(Java required)
chen_calzone_csikasznagy_cross_novak_tyson_2004
Integrative Analysis of Cell Cycle Control in Budding Yeast
- chen_calzone_csikasznagy_cross_novak_tyson_2004: View MML (Java required)
chen_csikasz-nagy_gyorffy_val_novak_tyson_2000
Kinetic Analysis of a Molecular Model of the Budding Yeast Cell Cycle
- chen_csikasz-nagy_gyorffy_val_novak_tyson_2000: View MML (Java required)
chen_popel_2006
Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells
- chen_popel_2006: View MML (Java required)
chen_popel_2007
Vascular and perivascular nitric oxide release and transport: biochemical pathways of neuronal nitric oxide synthase (NOS1) and endothelial nitric oxide synthase (NOS3)
- chen_popel_2007_b: View MML (Java required)
- chen_popel_2007_c: View MML (Java required)
cheng_brown_loeb_2000
Virtual muscle: a computational approach to understanding the effects of muscle properties on motor control
- cheng_brown_loeb_2000: View MML (Java required)
ciliberto_novak_tyson_2003
Mathematical Model of the Morphogenesis Checkpoint in Budding Yeast
- ciliberto_novak_tyson_2003: View MML (Java required)
ciliberto_petrus_tyson_sible_2003
A kinetic model of the cyclin E/Cdk2 developmental timer in Xenopus
- ciliberto_petrus_tyson_sible_2003: View MML (Java required)
ciliberto_tyson_2000
Mathematical Model for Early Development of the Sea Urchin Embryo
- ciliberto_tyson_2000: View MML (Java required)
clancy_rudy_2001
Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death
- clancy_rudy_2001: View MML
(Java required)
- clancy_rudy_2001_IKrN629D_Epi_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2001_IKrN629D_Mcell_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2001_IKrR56Q_Epi_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2001_IKrR56Q_Mcell_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2001_IKrT474I_Epi_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2001_IKrT474I_Mcell_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2001_INaKPQ_Epi_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2001_WT_Mcell_seconds_flooristim: View MML
(Java required)
clancy_rudy_2002
Na Channel Mutation That Causes Both Brugada Syndrome and Long-QT Syndrome Phenotypes: A Simulation Study of Mechanism
- clancy_rudy_2002: View MML
(Java required)
- clancy_rudy_2002_INa1795insD_Endo_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2002_INa1795insD_Epi_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2002_INa1795insD_Mcell_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2002_WT_Endo_seconds_flooristim: View MML
(Java required)
- clancy_rudy_2002_WT_Mcell_seconds_flooristim: View MML
(Java required)
cloutier_2009
An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements
- cloutier_2009: View MML (Java required)
cloutier_wellstead_2009
The control systems structures of energy metabolism
- cloutier_2009_a: View MML (Java required)
- cloutier_2009_b: View MML (Java required)
- cloutier_2009_c: View MML (Java required)
- cloutier_2009_d: View MML (Java required)
- cloutier_2009_e: View MML (Java required)
- cloutier_2009_f: View MML (Java required)
colegrove_albrecht_friel_2000
Quantitive Analysis of Mitochondrial Ca2+ Uptake and Release Pathways in Sympathetic Neurons Reconstruction of the Recovery after Depolarisation-evoked [Ca2+] Elevations
- colegrove_albrecht_friel_2000: View MML (Java required)
conradie_bruggeman_ciliberto_csikasz-nagy_novak_westerhoff_snoep_2010
Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex
- conradie_2010: View MML (Java required)
- cooling_hunter_crampin_2007: View MML (Java required)
- NFATCycling_DualProtocol: View MML (Java required)
- NFATCycling_ShenProtocol: View MML (Java required)
- NFATCycling_TomidaProtocol: View MML (Java required)
- NFATMyocyte_DualProtocol_Submodel: View MML
(Java required)
- NFATMyocyte_ShenProtocol_Submodel: View MML (Java required)
- NFATMyocyte_TomidaProtocol_Submodel: View MML (Java required)
- calcineurin_DualProtocol: View MML (Java required)
- calcineurin_ShenProtocol: View MML (Java required)
- calcineurin_TomidaProtocol: View MML (Java required)
- calcium_DualProtocol: View MML
(Java required)
- calcium_ShenProtocol: View MML (Java required)
- calcium_TomidaProtocol: View MML (Java required)
cooling_hunter_crampin_CellML_2008
- GPCR_Cycle: View MML (Java required)
- Galpha: View MML (Java required)
- IP3: View MML (Java required)
- IP3Submodel_Main: View MML (Java required)
- IP3_degradation: View MML (Java required)
- PIP2: View MML (Java required)
- PLC_Cycle: View MML (Java required)
- calcium: View MML (Java required)
- extracellular_ligand: View MML (Java required)
corrias_buist_2007
Corrias, Buist, 2007
- corrias_buist_2007: View MML (Java required)
corrias_buist_2008
Quantitative cellular description of gastric slow wave activity
- corrias_buist_2008: View MML (Java required)
cortassa_aon_marban_winslow_orourke_2003
An Integrated Model of Cardiac Mitrochondrial Energy Metabolism and Calcium Dynamics
- cortassa_aon_marban_winslow_orourke_2003: View MML (Java required)
cortassa_aon_winslow_orourke_2004
A mitochondrial oscillator dependent on reactive oxygen species
- cortassa_aon_winslow_orourke_2004: View MML (Java required)
costa_holmes_mcculloch_2001
Modelling Cardiac Mechanical Properties In Three Dimensions
- costa_holmes_mcculloch_2001: View MML (Java required)
courtemanche_ramirez_nattel_1998
Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model
- courtemanche_ramirez_nattel_1998: View MML (Java required)
cronwright_rohwer_prior_2002
Metabolic Control Analysis of Glycerol Synthesis in Saccharomyces cerevisiae
- cronwright_rohwer_prior_2002: View MML (Java required)
csilkasz_nagy_2006
Analysis of a generic model of eukaryotic cell-cycle regulation: budding yeast taken from the original model code
- csikasz_nagy_2006_budding_yeast_from_code: View MML (Java required)
- csikasz_nagy_2006_budding_yeast_from_paper: View MML (Java required)
- csikasz_nagy_2006_mammalian_from_code: View MML (Java required)
cui_kaandorp_2006
Mathematical modeling of calcium homeostasis in yeast cells
- cui_kaandorp_2006: View MML (Java required)
cui_kaandorp_2008
Simulating Complex Calcium-Calcineurin Signaling Network
- cui_kaandorp_2008: View MML (Java required)
cui_kaandorp_lloyd_2008
Simulating in vitro transcriptional response of zinc homeostasis system in Escherichia coli
- cui_kaandorp_lloyd_2008_a: View MML (Java required)
- cui_kaandorp_lloyd_2008_b: View MML (Java required)
curien_ravanel_dumas_2003
A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana
- curien_ravanel_dumas_2003: View MML (Java required)
dash_bassingthwaighte_2004
Blood HbO2 and HbCO2 dissociation curves at varied O2, CO2, pH, 2,3-DPG and temperature levels
- dash_bassingthwaighte_2004: View MML
(Java required)
dawson_lea_irvine_2003
Kinetic model of the inositol trisphosphate receptor that shows both steady-state and quantal patterns of Ca2+ release from intracellular stores
- dawson_lea_irvine_2003: View MML (Java required)
decker_2009
Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium
- decker_2009: View MML (Java required)
demir_clark_giles_1999
Parasympathetic modulation of sinoatrial node pacemaker activity in rabbit heart: a unifying model
- demir_clark_giles_1999: View MML (Java required)
demir_clark_giles_murphey_1994
A Mathematical Model of a Rabbit Sinoatrial Node Cell
- demir_clark_giles_murphey_1994: View MML (Java required)
demiray_1981
Large deformation analysis of some soft biological tissues
- demiray_1981: View MML (Java required)
dempsher_gann_phair_1984
A mechanistic model of ACTH-stimulated cortisol secretion
- dempsher_gann_phair_1984: View MML (Java required)
depaor_timmons_1986
A feedback oscillator model for circulatory autoregulation
- depaor_timmons_1986: View MML (Java required)
devries_sherman_2000
Channel Sharing in Pancreatic Beta-Cells Revisited: Enhancement of Emergent Bursting by Noise
- devries_sherman_2000: View MML
(Java required)
devries_sherman_2001
From Spikers to Bursters Via Coupling: Help from Heterogeneity
- devries_sherman_2001: View MML
(Java required)
deyoung_keizer_1992
A single-pool inositol 1,4,5-triphosphate-receptor-based model for agonist-stimulated oscillations in Ca 2+ concentration
- deyoung_keizer_1992: View MML
(Java required)
difrancesco_noble_1985
A Model of Cardiac Electrical Activity Incorporating Ionic Pumps and Concentration Changes
- difrancesco_noble_1985: View MML (Java required)
dijkstra_neal_beever_france_1992
Simulation of nutrient digestion, absorption and outflow in the rumen: model description
- dijkstra_1992: View MML (Java required)
dixit_perelson_2004
Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delay
- dixit_perelson_2004: View MML
(Java required)
dokos_celler_lovell_1996
Ion currents underlying sinoatrial node pacemaker activity: a new single cell mathematical model
- dokos_celler_lovell_1996: View MML (Java required)
- dokos_celler_lovell_b_1996: View MML
(Java required)
dougherty_wright_yew_2005
Computational model of the cAMP-mediated sensory response and calcium-dependent adaptation in vertebrate olfactory receptor neurons
- dougherty_wright_yew_2005: View MML (Java required)
drouhard_roberge_1987
Revised formulation of the Hodgkin-Huxley representation of the sodium current in cardiac cells
- drouhard_roberge_1987: View MML
(Java required)
dumaine_towbin_brugada_vatta_nesterenko_nesterenko_brugada_brugada_antzelevitch_1999
Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada Syndrome are temperature dependent
- dumaine_towbin_brugada_vatta_nesterenko_nesterenko_brugada_brugada_antzelevitch_1999: View MML
(Java required)
dupont_berridge_goldbeter_1991
Signal-induced Ca2+ oscillations: Properties of a model based on (Ca2+)-induced Ca2+ release
- dupont_1991a: View MML (Java required)
- dupont_1991a_1.1model: View MML (Java required)
- dupont_1991b: View MML (Java required)
- dupont_1991b_1.1model: View MML (Java required)
dupont_goldbeter_1992
Protein phosphorylation driven by intracellular calcium oscillations: A kinetic analysis
- dupont_1992_1.1model: View MML (Java required)
- dupont_1992a: View MML (Java required)
- dupont_1992b: View MML (Java required)
- dupont_1992b_1.1model: View MML (Java required)
earm_noble_1990
A Model of the Single Atrial Cell: Relation between Calcium Current and Calcium Release
- earm_noble_1990: View MML (Java required)
ebihara_johnson_1980
Fast sodium current in cardiac muscle: A quantitative description
- ebihara_johnson_1980: View MML
(Java required)
egli_bertram_sellix_freeman_2004
Rhythmic secretion of prolactin in rats: action of oxytocin coordinated by vasoactive intestinal polypeptide of suprachiasmatic nucleus origin
- egli_bertram_sellix_freeman_2004: View MML (Java required)
elowitz_leibler_2000
A Synthetic Oscillatory Network of Transciptional Regulators
- elowitz_leibler_2000: View MML (Java required)
enciso_sontag_2004
On the stability of a model of testosterone dynamics
- enciso_sontag_2004: View MML (Java required)
endresen_1996
Chaos in Weakly-coupled Pacemaker Cells
- endresen_1996: View MML (Java required)
eskandari_wright_loo_2005
Kinetics of the Reverse Mode of the Na+/Glucose Cotransporter
- Eskandari_et_al_2005: View MML (Java required)
espinosa_1998
L'Echange Na+/Ca2+ dans l'Hypertrophie Ventriculaire D'Altitude chez le Rat: Etude Electrophysiologique et Utilisation du Modele "Oxsoft Heart"
- espinosa_1998_hypertrophic: View MML (Java required)
- espinosa_1998_normal: View MML (Java required)
evans_errington_shelly_feeney_chapman_godfrey_smith_chappell_2004
A mathematical model for the in vitro kinetics of the anti-cancer agent topotecan
- evans_errington_shelly_feeney_chapman_godfrey_smith_chappell_2004: View MML (Java required)
faber_rudy_2000
Action potential and contractility changes in [Na(+)](i) overloaded cardiac myocytes: a simulation study.
- faber_rudy_2000: View MML (Java required)
- faber_rudy_modified_version_2000: View MML (Java required)
fall_keizer_2001
Mitochondrial Modulation of Intracellular Ca2+ Signalling
- fall_keizer_2001: View MML
(Java required)
fallon_lauffenburger_2000
Computational Model for Effects of Ligand/Receptor Binding Properties on Interleukin-2 Trafficking Dynamics and T Cell Proliferation Response
- fallon_lauffenburger_2000: View MML (Java required)
farhy_bowers_veldhuis_2007
Model-projected mechanistic bases for sex differences in growth hormone regulation in humans.
- farhy_bowers_veldhuis_2007_a: View MML (Java required)
- farhy_bowers_veldhuis_2007_b: View MML (Java required)
faville_pullan_sanders_koh_lloyd_smith_2009
- faville_model_2008: View MML (Java required)
- faville_pacemaker_unit_2008: View MML (Java required)
faville_pullan_sanders_smith_2008
A Biophysically Based Mathematical Model of Unitary Potential Activity in Interstitial Cells of Cajal
- faville_pullan_sanders_smith_2008: View MML (Java required)
fenton_karma_1998
Vortex dynamics in three-dimensional continuous myocardium with fiber rotation: Filament instability and fibrillation
- fenton_karma_1998_BR: View MML (Java required)
- fenton_karma_1998_GP: View MML (Java required)
- fenton_karma_1998_MBR: View MML (Java required)
- fenton_karma_1998_MLR1: View MML (Java required)
- fenton_karma_2006: View MML
(Java required)
fink_noble_virag_varro_giles_2008
Contributions of HERG K+ current to repolarization of the human ventricular action potential
- fink_noble_virag_varro_giles_2008: View MML (Java required)
fink_slepchenko_loew_1999
Determination of time-dependent inositol-1,4,5-triphosphate concentrations during calcium release in a smooth muscle cell
- fink_slepchenko_loew_1999: View MML (Java required)
fink_slepchenko_moraru_watras_schaff_loew_2000
An image-based model of calcium waves in differentiated neuroblastoma cells
- fink_slepchenko_moraru_watras_schaff_loew_2000: View MML
(Java required)
fitzhugh_1961
Impulses and Physiological States in Theoretical Models of Nerve Membrane
- fitzhugh_1961: View MML (Java required)
flynn_green_pedley_boxer_dearling_watson_boden_begent_2002
A Model-Based Approach for the Optimization of Radioimmunotherapy through Antibody Design and Radionuclide Selection
- flynn_green_pedley_boxer_dearling_watson_boden_begent_2002: No JSim version is currently available. (View error log)
fohlmeister_miller_1997
Impulse Encoding Mechanisms of Ganglion Cells in the Tiger Salamander Retina
- fohlmeister_miller_1997: View MML
(Java required)
fox_mcharg_gilmour_2002
Ionic mechanism of electrical alternans
- fox_mcharg_gilmour_2002: View MML (Java required)
fridlyand_tamarina_philipson_2003
Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores
- fridlyand_tamarina_philipson_2003: View MML
(Java required)
- friel_1995: View MML (Java required)
fujita_toyoshima_uda_ozaki_kubota_kuroda_2010
Decoupling of receptor and downstream signals in the Akt pathway by its low-pass filter characteristics
- fujita_2010_EGFR_inhibited_Akt: View MML (Java required)
- fujita_2010_EGF_dependent_Akt: View MML (Java required)
- fujita_2010_NGF_dependent_Akt: View MML (Java required)
gall_susa_1999
Effect of Na/Ca Exchange on Plateau Fraction and [Ca]i in Models for Bursting in Pancreatic Beta-Cells
- gall_susa_1999_a: View MML (Java required)
- gall_susa_1999_b: View MML (Java required)
- gall_susa_1999_c: View MML (Java required)
gardner_dolnik_collins_1998
A theory for controlling cell cycle dynamics using a reversibly binding inhibitor
- gardner_dolnik_collins_1998: View MML (Java required)
garmendia-torres_goldbeter_jacquet_2007
- Msn2_fractions: View MML (Java required)
- V_rates: View MML
(Java required)
- garmendiatorres_2007: View MML (Java required)
- garmendiatorres_2007_1.1model: No JSim version is currently available. (View error log)
- nucleocytoplasm: View MML (Java required)
- process_fractions: View MML (Java required)
- subunits: View MML (Java required)
garny_kohl_hunter_boyett_noble_2003
One-dimensional Rabbit Sinoatrial Node Models: Benefits and Limitations
- garny_kohl_hunter_boyett_noble_2003: View MML (Java required)
gasser_ogden_holzapfel_2006
Hyperelastic modelling of arterial layers with distributed collagen fibre orientations
- gasser_ogden_holzapfel_2006_a: View MML (Java required)
- gasser_ogden_holzapfel_2006_b: View MML (Java required)
gerard_goldbeter_2009
Temporal self-organization of the cyclin/Cdk network driving the mammalian cell cycle
- gerard_2009: View MML (Java required)
gilbert_heiner_rosser_fulton_gu_trybilo_2007
A Case Study in Model-driven Synthetic Biology
- gilbert_heiner_rosser_fulton_gu_trybilo_2007: View MML (Java required)
goforth_bertram_khan_zhang_sherman_satin_2002
Calcium-activated K+ Channels of Mouse Beta Cells are Controlled by Both Store and Cytoplasmic Ca2+: Experimental and Theoretical Studies
- goforth_bertram_khan_zhang_sherman_satin_2002: View MML
(Java required)
- goldbeter_1991: View MML (Java required)
- goldbeter_1991_1.1: View MML
(Java required)
- goldbeter_1991_constitutive_law1: No JSim version is currently available. (View error log)
- goldbeter_1991_constitutive_law2: No JSim version is currently available. (View error log)
- goldbeter_1991_units: View MML (Java required)
- goldbeter_annotated_1991: View MML (Java required)
- goldbeter_1995: View MML (Java required)
- goldbeter_1995_1.1: View MML (Java required)
- goldbeter_1995_units: View MML (Java required)
- goldbeter_2006: View MML (Java required)
- goldbeter_2006_1.1: View MML (Java required)
- goldbeter_2006_law1: No JSim version is currently available. (View error log)
- goldbeter_2006_units: View MML (Java required)
goldbeter_dupont_berridge_1990
- goldbeter_1990_1.1: View MML (Java required)
- goldbeter_1990_units: View MML (Java required)
- goldbeter_dupont_berridge_1990: View MML (Java required)
- goldbeter_2007: View MML (Java required)
- goldbeter_2007_1.1: View MML (Java required)
- goldbeter_2007_law1: No JSim version is currently available. (View error log)
- goldbeter_2007_units: View MML (Java required)
goldbeter_pourquie_2008
Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways
- goldbeter_pourquie_2008_a: View MML (Java required)
- goldbeter_pourquie_2008_b: View MML (Java required)
gonzalezheydrich_steingard_kohane_1994
A computer simulation of the hypothalamic-pituitary-adrenal axis
- gonzalezheydrich_steingard_kohane_1994: View MML (Java required)
goodwin_1965
Oscillatory behavior in enzymatic control processes
- goodwin_1965_a: View MML (Java required)
- goodwin_1965_b: View MML (Java required)
- goodwin_1965_c: View MML (Java required)
- grandi_2010_envelope: View MML (Java required)
- grandi_2010_iv: View MML (Java required)
- grandi_2010_none: View MML (Java required)
- grandi_2010_pace1: View MML (Java required)
- grandi_2010_pace2: View MML (Java required)
- grandi_2010_pace4: View MML (Java required)
- grandi_2010_pacenew: View MML (Java required)
- grandi_2010_recovery: View MML (Java required)
- grandi_2010_vclamp: View MML (Java required)
- grandi_pasqualini_bers_2010: View MML (Java required)
- grandi_pasqualini_bers_2010_flat: View MML (Java required)
grange_2001
A pharmacokinetic model to predict the PK interaction of L-dopa and benserazide in rats
- grange_2001: View MML (Java required)
- grange_2001_bens: View MML (Java required)
greenstein_wu_po_tomaselli_winslow_2000
Role of the Calcium-Independent Transient Outward Current Ito1 in Shaping Action Potential Morphology and Duration
- greenstein_wu_po_tomaselli_winslow_2000: View MML
(Java required)
- gross_and_hopfer_1998: View MML (Java required)
- gross_and_hopfer_1999: View MML (Java required)
grossman_feinberg_kuznetsov_dimitrov_paul_1998
HIV infection: how effective is drug combination treatment?
- grossman_feinberg_kuznetsov_dimitrov_paul_1998: View MML
(Java required)
guccione_mcculloch_waldman_1991
Passive Material Properties of Intact Ventricular Myocardium Determined From a Cylindrical Model
- guccione_mcculloch_waldman_1991: View MML (Java required)
gupta_aslakson_gurbaxani_vernon_2007
Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability
- gupta_aslakson_gurbaxani_vernon_2007_a: View MML
(Java required)
- gupta_aslakson_gurbaxani_vernon_2007_b: View MML (Java required)
gupta_maurya_stephens_dennis_subramanium_2009
An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis
- gupta_2009: View MML (Java required)
guyton_2008
Description of Guyton 1992 Full Cardiovascular Circulation Model
- Guyton_Model_1-0: No JSim version is currently available. (View error log)
- aldosterone: No JSim version is currently available. (View error log)
- aldosterone_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_aldosterone_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
- angiotensin: No JSim version is currently available. (View error log)
- angiotensin_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_angiotensin_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_antidiuretic_hormone_2008
- antidiuretic_hormone: No JSim version is currently available. (View error log)
- antidiuretic_hormone_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_antidiuretic_hormone_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_atrial_natriuretic_peptide_2008
- atr_natriuretic_peptide: No JSim version is currently available. (View error log)
- atr_natriuretic_peptide_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_atrial_natriuretic_peptide_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
- autonomics: No JSim version is currently available. (View error log)
- autonomics_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_autonomics_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_capillary_dynamics_2008
- cap_dynamics: No JSim version is currently available. (View error log)
- cap_dynamics_parent: View MML
(Java required)
- environment: View MML (Java required)
- guyton_capillary_dynamics_2008: View MML
(Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_circulatory_dynamics_2008
- circulation: No JSim version is currently available. (View error log)
- circulation_parent: View MML
(Java required)
- environment: View MML (Java required)
- guyton_circulatory_dynamics_2008: View MML
(Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
- electrolytes: No JSim version is currently available. (View error log)
- electrolytes_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_electrolytes_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_heart_hypertrophy_or_deterioration_2008
- environment: View MML (Java required)
- guyton_heart_hypertrophy_or_deterioration_2008: View MML (Java required)
- hypertrophy_or_deterioration: No JSim version is currently available. (View error log)
- hypertrophy_or_deterioration_parent: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_heart_rate_and_stroke_volume_2008
- HR_and_SV: No JSim version is currently available. (View error log)
- HR_and_SV_parent: View MML
(Java required)
- environment: View MML (Java required)
- guyton_heart_rate_and_stroke_volume_2008: View MML
(Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
- environment: View MML (Java required)
- guyton_kidney_2008: No JSim version is currently available. (View error log)
- kidney: No JSim version is currently available. (View error log)
- kidney_parent: No JSim version is currently available. (View error log)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_muscle_blood_flow_control_2008
- M_blood_flow: No JSim version is currently available. (View error log)
- M_blood_flow_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_muscle_blood_flow_control_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_muscle_oxygen_delivery_2008
- M_O2_delivery: No JSim version is currently available. (View error log)
- M_O2_delivery_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_muscle_oxygen_delivery_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_non_muscle_blood_flow_control_2008
- NM_blood_flow: No JSim version is currently available. (View error log)
- NM_blood_flow_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_non_muscle_blood_flow_control_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_non_muscle_oxygen_delivery_2008
- NM_O2_Delivery: No JSim version is currently available. (View error log)
- NM_O2_Delivery_parent: View MML (Java required)
- environment: View MML (Java required)
- guyton_non_muscle_oxygen_delivery_2008: View MML (Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
guyton_pulmonary_fluid_dynamics_2008
- environment: View MML (Java required)
- guyton_pulmonary_fluid_dynamics_2008: View MML (Java required)
- parameters: View MML (Java required)
- pulmonary_fluid: No JSim version is currently available. (View error log)
- pulmonary_fluid_parent: View MML (Java required)
- units: View MML (Java required)
guyton_pulmonary_oxygen_uptake_2008
- environment: View MML (Java required)
- guyton_pulmonary_oxygen_uptake_2008: View MML (Java required)
- parameters: View MML (Java required)
- pulmonary_O2: No JSim version is currently available. (View error log)
- pulmonary_O2_parent: View MML (Java required)
- units: View MML (Java required)
guyton_red_cells_and_viscosity_2008
- environment: View MML (Java required)
- guyton_red_cells_and_viscosity_2008: View MML (Java required)
- parameters: View MML (Java required)
- red_cells: No JSim version is currently available. (View error log)
- red_cells_parent: View MML (Java required)
- units: View MML (Java required)
- environment: View MML (Java required)
- guyton_stress_relaxation_2008: View MML (Java required)
- parameters: View MML (Java required)
- stress: No JSim version is currently available. (View error log)
- stress_parent: View MML (Java required)
- units: View MML (Java required)
guyton_thirst_drinking_and_salt_appetite_2008
- environment: View MML (Java required)
- guyton_thirst_drinking_and_salt_appetite_2008: View MML (Java required)
- parameters: View MML (Java required)
- thirst: No JSim version is currently available. (View error log)
- thirst_parent: View MML (Java required)
- units: View MML (Java required)
- environment: View MML (Java required)
- guyton_volume_receptors_2008: View MML
(Java required)
- parameters: View MML (Java required)
- units: View MML (Java required)
- volume_receptors: No JSim version is currently available. (View error log)
- volume_receptors_parent: View MML
(Java required)
hai_murphy_1988
Cross-bridge phosphorylation and regulation of latch state in smooth muscle
- hai_1988: View MML (Java required)
halloy_bernard_loussouarn_goldbeter_2002
- Y: No JSim version is currently available. (View error log)
- Y_0: No JSim version is currently available. (View error log)
- fraction: View MML (Java required)
- halloy_2002_1.1: View MML (Java required)
- halloy_bernard_loussouarn_goldbeter_2002: View MML (Java required)
hatakeyama_kimura_naka_kawasaki_yumoto_ichikawa_kim_saito_saeki_shirouzu_yokoyama_konagaya_2003
A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling
- hatakeyama_kimura_naka_kawasaki_yumoto_ichikawa_kim_saito_saeki_shirouzu_yokoyama_konagaya_2003: View MML (Java required)
hatzimanikatis_lee_bailey_1999
A mathematical description of regulation of the G1-S transition of the mammalian cell cycle
- hatzimanikatis_lee_bailey_1999: View MML (Java required)
haugh_2004
Mathematical model of human growth hormone (hGH)-stimulated cell proliferation explains the efficacy of hGH variants as receptor agonists or antagonists
- haugh_2004: View MML (Java required)
- haugh_2004b: View MML (Java required)
heinze_keener_midgley_1998
A mathematical model of luteinizing hormone release from ovine pituitary cells in perifusion
- heinze_keener_midgley_1998_a: View MML (Java required)
- heinze_keener_midgley_1998_b: View MML (Java required)
- heinze_keener_midgley_1998_c: View MML (Java required)
heldt_2002
Computational modeling of cardiovascular response to orthostatic stress
- circ_pbpk: View MML
(Java required)
- heart: View MML
(Java required)
- lpc: View MML
(Java required)
herz_bonhoeffer_anderson_may_nowak_1996
Viral Dynamics in vivo: Limitations on estimates of intracellular delay and virus decay
- herz_bonhoeffer_anderson_may_nowak_1996: View MML
(Java required)
heyd_drew_2003
A mathematical model for elongation of a peptide chain
- heyd_drew_2003: View MML (Java required)
hilgemann_noble_1987
Excitation-contraction coupling and extracellular calcium transients in rabbit atrium: reconstruction of basic cellular mechanisms
- hilgemann_noble_1987: View MML (Java required)
hinch_greenstein_tanskanen_xu_winslow_2004
A Simplified Local Control Model of Calcium-Induced Calcium Release in Cardiac Ventricular Myocytes
- hinch_greenstein_tanskanen_xu_winslow_2004: View MML (Java required)
hodgkin_huxley_1952
A quantitative description of membrane current and its application to conductance and excitation in nerve
- hodgkin_huxley_1952: View MML (Java required)
- hodgkin_huxley_1952_variant01: View MML (Java required)
hoefnagel_starrenburg_martens_hugenholtz_kleerebezem_vanswam_bongers_westerhoff_snoep_2002
Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis
- hoefnagel_starrenburg_martens_hugenholtz_kleerebezem_vanswam_bongers_westerhoff_snoep_2002: View MML (Java required)
holmes_2006
Teaching from classic papers: Hill's model of muscle contraction
- holmes_2006: View MML (Java required)
hornberg_binder_bruggeman_schoeberl_heinrich_westerhoff_2005
Control of MAPK signalling: from complexity to what really matters
- hornberg_binder_bruggeman_schoeberl_heinrich_westerhoff_2005: View MML (Java required)
- constitutive_law1: View MML
(Java required)
- constitutive_law2: View MML (Java required)
- houart_1999: View MML (Java required)
- houart_1999_1.0: View MML (Java required)
- houart_1999_1.1: View MML (Java required)
huang_ferrell_1996
Ultrasensitivity in the mitogen-activated protein kinase cascade
- huang_ferrell_1996: View MML (Java required)
hund_rudy_2004
Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model
- hund_rudy_2004_a: View MML (Java required)
- hund_rudy_2004_b: View MML (Java required)
hunter_mcculloch_terkeurs_1998
Modelling the mechanical properties of cardiac muscle
- hunter_mcculloch_terkeurs_1998: View MML
(Java required)
hunter_mcnaughton_noble_1975
Analytical models of propagation in excitable cells
- hunter_mcnaughton_noble_1975: View MML
(Java required)
hunter_smaill_hunter_1995
A pole-zero constitutive law for myocardium
- hunter_smaill_hunter_1995: View MML (Java required)
hynne_dano_sorensen_2001
Full-scale model of glycolysis in Saccharomyces cerevisiae
- hynne_dano_sorensen_2001: View MML (Java required)
iancu_2007
Compartmentation of cAMP signaling in cardiac myocytes: a computational study
- iancu_jones_harvey_2007: View MML (Java required)
iber_maini_2002
A Mathematical Model for Germinal Centre Kinetics and Affinity Maturation
- iber_maini_2002: View MML
(Java required)
inada_2009
One-dimensional mathematical model of the atrioventricular node including atrio-nodal, nodal, and nodal-his cells
- inada_AN_2009: View MML (Java required)
- inada_NH_2009: View MML (Java required)
- inada_N_2009: View MML (Java required)
international_si_units_2006
International SI Units, 2006
- international_si_units_2006: View MML (Java required)
iribe_kohl_noble_2006
Modulatory effect of calmodulin-dependent kinase II (CaMKII) on sarcoplasmic reticulum Ca2+ handling and interval-force relations: a modelling study.
- iribe_kohl_noble_2006: View MML (Java required)
irvine_jafri_winslow_1999
Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation
- irvine_jafri_winslow_1999: View MML (Java required)
itskov_ehret_mavrilas_2006
A Polyconvex Anisotropic Strain-Energy Function for Soft Collagenous Tissues
- itskov_ehret_mavrilas_2006: No JSim version is currently available. (View error log)
iyer_hajjar_armoundas_2007
Mechanisms of Abnormal Calcium Homeostasis in Mutations Responsible for Catecholaminergic Polymorphic Ventricular Tachycardia
- iyer_2007_ss: View MML (Java required)
iyer_mazhari_winslow_2004
A computational model of the human left-ventricular epicardial myocyte
- iyer_mazhari_winslow_2004: View MML (Java required)
izakov_katsnelson_blyakhman_markhasin_shkylar_1991
Cooperative Effects Due to Calcium Binding by Troponin and Their Consequences for Contraction and Relaxation of Cardiac Muscle Under Various Conditions of Mechanical Loading
- izakov_katsnelson_blyakhman_markhasin_shkylar_1991: View MML (Java required)
jafri_rice_winslow_1998
Cardiac Ca2+ Dynamics: The Roles of Ryanodine Receptor Adaptation and Sarcoplasmic Reticulum Load
- jafri_rice_winslow_1998_a: View MML (Java required)
- jafri_rice_winslow_1998_b: View MML (Java required)
jelic_cupic_kolaranic_2005
A Hypothalamic-Pituitary-Adrenal System Model: Full Model
- jelic_cupic_kolaranic_2005: View MML (Java required)
- jelic_cupic_kolaranic_2005_Fig4: View MML (Java required)
- jelic_cupic_kolaranic_2005_Fig5: View MML (Java required)
joseph_zavros_merchant_kirschner_2003
A model for integrative study of human gastric acid secretion
- joseph_zavros_merchant_kirschner_2003: View MML
(Java required)
karagiannis_popel_2004
A theoretical model of type I collagen proteolysis by matrix metalloproteinase (MMP) 2 and membrane type 1 MMP in the presence of tissue inhibitor of metalloproteinase 2
- karagiannis_popel_2004: View MML (Java required)
karagiannis_popel_2006
Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model
- karagiannis_popel_2006: View MML (Java required)
katsnelson_nikitina_chemla_solovyova_coirault_lecarpentier_markhasin_2004
Influence of viscosity on myocardium mechanical activity: a mathematical model
- katsnelson_2004a: View MML (Java required)
- katsnelson_2004b: View MML (Java required)
- katsnelson_2004c: View MML (Java required)
keener_2001
Diffusion Induced Oscillatory Insulin Secretion
- keener_2001: No JSim version is currently available. (View error log)
keizer_levine_1996
Ryanodine Receptor Adaptation and Ca2+-Induced Ca2+ Release-Dependent Ca2+ Oscillations
- keizer_levine_1996: View MML
(Java required)
kesmir_deboer_1999
A Mathematical Model on Germinal Center Kinetics and Termination
- kesmir_deboer_1999: View MML (Java required)
kholodenko_demin_moehren_hoek_1999
Quantification of short term signalling by the epidermal growth
- kholodenko_demin_moehren_hoek_1999: View MML (Java required)
kirschner_panetta_1998
Modeling immunotherapy of the tumor-immune interaction
- kirschner_panetta_1998: View MML (Java required)
kirschner_webb_1996
A Model For Treatment Strategy In The Chemotherapy Of AIDS
- kirschner_webb_1996: No JSim version is currently available. (View error log)
kneller_ramirez_chartier_courtemanche_nattel_2002
Time-dependent transients in an ionically based mathematical model of the canine atrial action potential
- kneller_ramirez_chartier_courtemanche_nattel_2002: No JSim version is currently available. (View error log)
koivumaki_2009
Modelling Sarcoplasmic Reticulum Calcium APTase and its Regulation in Cardiac Myocytes
- koivumaki_takalo_korhonen_tavi_weckstrom_2009_reduced_myocyte_long: View MML
(Java required)
- koivumaki_takalo_korhonen_tavi_weckstrom_2009_reduced_myocyte_short: View MML
(Java required)
- koivumaki_takalo_korhonen_tavi_weckstrom_2009_standalone: View MML (Java required)
komarova_2005
Mathematical model of paracrine interactions between osteoclasts and osteoblasts predicts anabolic action of parathyroid hormone on bone
- komarova_2005: View MML
(Java required)
komarova_smith_dixon_sims_wahl_2003
Mathematical model predicts a critical role for osteoclast autocrine regulation in the control of bone remodeling
- komarova_2003: View MML
(Java required)
- komarova_2003b: View MML
(Java required)
komarova_wodarz_2003
Evolutionary Dynamics of Mutator Phenotypes in Cancer: Implications for Chemotherapy
- komarova_wodarz_2003_complex: View MML (Java required)
- komarova_wodarz_2003_simple: View MML (Java required)
kongas_vanbeek_2001
Creatine kinase in energy metabolic signaling in muscle
- kongas_vanbeek_2001: View MML (Java required)
korzeniewski_zoladz_2001
A model of oxidative phosphorylation in mammaliam skeletal muscle
- korzeniewski_zoladz_2001: View MML
(Java required)
kroll_2000
Parathyroid hormone temporal effects on bone formation and resorption
- kroll_2000: View MML (Java required)
kurata_hisatome_imanishi_shibamoto_2002
Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell
- kurata_hisatome_imanishi_shibamoto_2002: View MML (Java required)
kyrylov_severyanova_vieira_2005
Modeling robust oscillatory behavior of the hypothalamic-pituitary-adrenal axis
- kyrylov_severyanova_vieira_2005: View MML (Java required)
lambeth_kushmerick_2002
A computational model for glycogenolysis in skeletal muscle
- lambeth_kushmerick_2002: View MML (Java required)
landesberg_sideman_1994
Mechanical regulation of cardiac muscle by coupling calcium kinetics with cross-bridge cycling: a dynamic model
- landesberg_sideman_1994: View MML
(Java required)
lebeau_robson_mckinnon_donald_sneyd_1997
Generation of Action Potentials in a Mathematical Model of Corticotrophs
- lebeau_robson_mckinnon_donald_sneyd_1997: View MML
(Java required)
lebeau_yule_groblewski_sneyd_1999
Agonist-dependent Phosphorylation of the Inositol 1,4,5-Triphosphate Receptor
- lebeau_yule_groblewski_sneyd_1999: View MML
(Java required)
- Stage0: View MML (Java required)
- Stage1: View MML (Java required)
- Stage2: View MML (Java required)
- Totals: View MML (Java required)
- leloup_1998a: View MML (Java required)
- leloup_1998a_1.1model: View MML (Java required)
- leloup_1998b: View MML (Java required)
- leloup_1998b_1.1model: View MML
(Java required)
- mRNAs: View MML
(Java required)
- law1: View MML (Java required)
- law2: View MML (Java required)
- law3: View MML (Java required)
- leloup_goldbeter_2003: View MML (Java required)
- leloup_goldbeter_2003_1.1model: View MML (Java required)
- mRNAs: View MML
(Java required)
- law1: View MML (Java required)
- law2: View MML (Java required)
- law3: View MML (Java required)
- leloup_2004_1.1model: View MML (Java required)
- leloup_goldbeter_2004: View MML (Java required)
- mRNAs: View MML
(Java required)
- law1: View MML
(Java required)
- law2: View MML (Java required)
- law3: View MML (Java required)
- law4: View MML (Java required)
- leloup_1999_1.1model: View MML (Java required)
- leloup_gonze_goldbeter_1999_a: View MML (Java required)
- leloup_gonze_goldbeter_1999_b: View MML (Java required)
- total: View MML (Java required)
lemaire_tobin_greller_cho_suva_2004
Modeling the interactions between osteoblast and osteoclast activities in bone remodeling
- lemaire_tobin_greller_cho_suva_2004: View MML (Java required)
- lemaire_tobin_greller_cho_suva_2004_a: View MML (Java required)
- lemaire_tobin_greller_cho_suva_2004_b: View MML (Java required)
- lemaire_tobin_greller_cho_suva_2004_c: View MML (Java required)
- lemaire_tobin_greller_cho_suva_2004_d: View MML (Java required)
- lemaire_tobin_greller_cho_suva_2004_e: View MML (Java required)
- lemaire_tobin_greller_cho_suva_2004_f: View MML (Java required)
- lemaire_tobin_greller_cho_suva_2004_g: View MML (Java required)
- lemaire_tobin_greller_cho_suva_2004_h: View MML (Java required)
- lemaire_tobin_greller_cho_suva_2004_i: View MML (Java required)
lemon_gibson_bennett_2003
Metabotropic receptor activation, desensitization and sequestration-I: modelling calcium and inositol 1,4,5-trisphosphate dynamics following receptor activation
- lemon_2003: View MML (Java required)
lenbury_pacheenburawana_1991
Modelling fluctuation phenomena in the plasma cortisol secretion system in normal man
- lenbury_pacheenburawana_1991: View MML (Java required)
lenbury_pornsawad_2005
A delay-differential equation model of the feedback-controlled hypothalamus-pituitary-adrenal axis in humans
- lenbury_pornsawad_2005: View MML (Java required)
lenbury_ruktamatakul_amornsamarnkul_2001
Modeling insulin kinetics: responses to a single oral glucose administration or ambulatory-fed conditions
- lenbury_ruktamatakul_amornsamarnkul_2001_a: View MML (Java required)
- lenbury_ruktamatakul_amornsamarnkul_2001_b: View MML (Java required)
li_bertram_rinzel_1996
Modeling N-methyl-D-aspartate-induced bursting in dopamine neurons
- li_1996_complex: View MML (Java required)
- li_1996_simple: View MML (Java required)
- li_1996_simple_from_paper: View MML (Java required)
li_kuang_mason_2006
Modeling the glucose-insulin regulatory system and ultradian insulin secretory oscillations with two explicit time delays
- li_kuang_mason_2006: View MML (Java required)
li_rinzel_1994
Equations for InsP3 Receptor-mediated [Ca2+]i Oscillations Derived from a Detailed Kinetic Model: A Hodgkin-Huxley Like Formalism
- li_rinzel_1994: View MML
(Java required)
- C57BL7_WT_model_version1: View MML (Java required)
- Li_Smith_2009_C57BL7_WT: View MML (Java required)
lindblad_murphey_clark_giles_1996
A Model of the Action Potential and Underlying Membrane Currents in a Rabbit Atrial Cell
- lindblad_murphey_clark_giles_1996: View MML (Java required)
liu_hu_peng_liu_1999
A dynamical model for the pulsatile secretion of the hypothalamo-pituitary-adrenal axis
- liu_hu_peng_liu_1999: View MML (Java required)
livshitz_rudy_2007
Regulation of Ca2+ and electrical alternans in cardiac myocytes: role of CAMKII and repolarizing currents
- livshitz_rudy_2007: View MML (Java required)
lockwood_ewy_hermann_holford_2006
Application of clinical trial simulation to compare proof-of-concept study designs for drugs with a slow onset of effect; an example in Alzheimer's disease
- lockwood_ewy_hermann_holford_2006: View MML (Java required)
lovell_cloherty_celler_dokos_2004
A gradient model of cardiac pacemaker myocytes
- lovell_cloherty_celler_dokos_2004: View MML
(Java required)
luo_rudy_1991
A Model of the Ventricular Cardiac Action Potential. Depolarization, repolarization and their interaction
- luo_rudy_1991: View MML (Java required)
luo_rudy_1994
A Dynamic Model of the Cardiac Ventricular Action Potential I. Simulations of Ionic Currents and Concentration Changes
- luo_rudy_1994: View MML
(Java required)
macgregor_leng_2005
Modelling the hypothalamic control of growth hormone secretion.
- macgregor_leng_2005_a: View MML (Java required)
- macgregor_leng_2005_b: View MML (Java required)
mackenzie_loo_panayotova-heiermann_wright_1996
Biophysical Characteristics of the Pig Kidney Na/Glucose Cotransporter SGLT2 Reveal a Common Mechanism for SGLT1 and SGLT2
- mackenzie_1996: View MML (Java required)
magnus_keizer_1997
Minimal Model of beta-cell mitochondrial Ca2+ handling
- magnus_keizer_1997: View MML
(Java required)
magnus_keizer_1998
Model of beta_cell mitochondrial calcium handling and electrical activity. I. Cytoplasmic variables
- magnus_keizer_1998: View MML
(Java required)
mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_restrepo_karma_garfinkel_qu_weiss_2008
A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates
- mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_restrepo_karma_garfinkel_qu_weiss_2008: View MML (Java required)
maldonado_borchers_findeisen_allgower_2006
Mathematical modeling and analysis of force induced bone growth
- maldonado_2006: View MML
(Java required)
maleckar_greenstein_trayanova_giles_2009
Mathematical simulations of ligand-gated and cell-type specific effects on the action potential of human atrium
- maleckar_greenstein_trayanova_giles_2009: View MML (Java required)
maltsev_2009
Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model.
- maltsev_2009_paper: View MML (Java required)
- maltsev_2009_steady_state: View MML (Java required)
maly_wiley_lauffenburger_2004
Self-Organization of Polarized Cell Signaling via Autocrine Circuits: Computational Model Analysis
- maly_wiley_lauffenburger_2004: No JSim version is currently available. (View error log)
- malys_2010: View MML (Java required)
marcano_yang_nievesgonzalez_clausen_moore_2009
- Marcano_et_al_2009_NaK2Cl_isoformA_Cl: View MML (Java required)
- Marcano_et_al_2009_NaK2Cl_isoformA_K: View MML (Java required)
- Marcano_et_al_2009_NaK2Cl_isoformA_Na: View MML (Java required)
- Marcano_et_al_2009_NaK2Cl_isoformA_Na_Net: View MML (Java required)
- Marcano_et_al_2009_NaK2Cl_isoformB_Cl: View MML (Java required)
- Marcano_et_al_2009_NaK2Cl_isoformB_K: View MML (Java required)
- Marcano_et_al_2009_NaK2Cl_isoformB_Na: View MML (Java required)
- Marcano_et_al_2009_NaK2Cl_isoformF_Cl: View MML (Java required)
- Marcano_et_al_2009_NaK2Cl_isoformF_K: View MML (Java required)
- Marcano_et_al_2009_NaK2Cl_isoformF_Na: View MML (Java required)
margaridamartins_mendes_coreiro_pocesfreire_2001
In situ kinetic analysis of glyoxalase I and glyoxalase II in Saccharomyces cerevisiae
- martins_mendes_coreiro_freire_2001: View MML (Java required)
marhl_haberichter_brumen_heinrich_2000
Complex calcium oscillations and the role of mitochondria and cytosolic proteins
- marhl_haberichter_brumen_heinrich_2000: View MML (Java required)
marhl_schuster_brumen_heinrich_1997
Modelling the interrelations between calcium oscillations and ER membrane potential oscillations
- marhl_schuster_brumen_heinrich_1997: View MML
(Java required)
martinov_vitvitsky_mosharov_banerjee_ataullakhanov_2000
A Substrate Switch: A New Mode of Regulation in the Methionine Metabolic Pathway
- martinov_vitvitsky_mosharov_banerjee_ataullakhanov_2000: View MML (Java required)
marwan_2003
Theory of Time-Resolved Somatic Complementation and Its Use to Explore the Sporulation Control Network in Physarum polycephalum
- marwan_2003: View MML
(Java required)
matsuoka_sarai_kuratomi_ono_noma_2003
Role of individual ionic current systems in ventricular cells hypothesized by a model study
- matsuoka_sarai_kuratomi_ono_noma_2003: View MML (Java required)
maurya_bornheimer_venkatasubramanian_subramaniam_2005
Reduced-order modelling of biochemical networks: application to the GTPase-cycle signalling module
- maurya_2005: View MML (Java required)
mazhari_greenstein_winslow_marban_nuss_2001
Molecular Interactions Between Two Long-QT Syndrome Gene Products, HERG and KCNE2, Rationalized by In Vitro and In Silico Analysis
- mazhari_greenstein_winslow_marban_nuss_2001: View MML
(Java required)
mcallister_noble_tsien_1975
Reconstruction of the electrical activity of cardiac Purkinje fibres.
- mcallister_noble_tsien_1975_a: View MML (Java required)
- mcallister_noble_tsien_1975_b: View MML (Java required)
mckenzie_sneyd_1998
On the Formation and Breakup of Spiral Waves of Calcium
- mckenzie_sneyd_1998: No JSim version is currently available. (View error log)
mclean_su_vandenbogert_2003
Development and Validation of a 3-D Model to Predict Knee Joint Loading During Dynamic Movement
- mclean_su_vandenbogert_2003: View MML (Java required)
mears_sheppard_atwater_rojas_bertram_sherman_1997
Evidence That Calcium Release-activated Current Mediates the Biphasic Electrical Activity of Mouse Pancreatic Beta-Cells
- mears_sheppard_atwater_rojas_bertram_sherman_1997: View MML (Java required)
michailova_mcculloch_2001
Model study of ATP and ADP buffering, transport of Ca2+ and Mg2+, and regulation of ion pumps in ventricular myocyte
- michailova_mcculloch_2001: View MML (Java required)
michailova_saucerman_belik_mcculloch_2005
Modeling regulation of cardiac KATP and L-type Ca2+ currents by ATP, ADP, and Mg2+
- michailova_2005: View MML (Java required)
miftakhov_abdusheva_christensen_1999
Numerical Simulation of Motility Patterns of the Small Bowel. I. Formulation of a Mathematical Model
- miftakhov_abdusheva_christensen_1999: View MML (Java required)
mijailovich_butler_fredburg_2000
Perturbed Equilibria of Myosin Binding in Airway Smooth Muscle: Bond-Length Distributions, Mechanics and ATP Metabolism
- mijailovich_butler_fredburg_2000: View MML (Java required)
mikane_araki_kohno_nakayama_suzuki_shimuzi_matsubara_hirakawa_takaki_suga_1997
Mechanism of Constant Contractile Efficiency Under Cooling Intropy of Myocardium: Simulation
- mikane_araki_kohno_nakayama_suzuki_shimuzi_matsubara_hirakawa_takaki_suga_1997: View MML (Java required)
mitchell_schaeffer_2003
A two-current model for the dynamics of cardiac membrane
- mitchell_schaeffer_2003: View MML (Java required)
mittler_sulzer_neumann_perelson_1998
Influence of delayed viral production on viral dynamics in HIV-1 infected patients
- mittler_sulzer_neumann_perelson_1998: View MML (Java required)
mlcek_neumann_kittnar_novak_2001
Mathematical Model of the Electromechanical Heart Contractile System - Regulatory Subsystem Physiological Considerations
- mlcek_neumann_kittnar_novak_2001: View MML
(Java required)
mohr_taylor_newell_2008
Mohr, Taylor, Newell, 2008
- mohr_taylor_newell_2008: View MML (Java required)
moore_li_2004
A mathematical model for chronic myelogenous leukemia (CML) and T cell interaction
- moore_li_2004: View MML (Java required)
- moore_li_2004b: View MML (Java required)
- moore_li_2004c: View MML (Java required)
morris_lecar_1981
Voltage oscillations in the barnacle giant muscle fiber
- morris_1981: View MML (Java required)
- morris_1981_reduced: View MML (Java required)
mosekilde_lading_yanchuk_maistrenko_2001
Bifurcation structure of a model of bursting pancreatic cells
- mosekilde_lading_yanchuk_maistrenko_2001: No JSim version is currently available. (View error log)
moss_kazmierczak_kirley_harris_2009
A computational model for emergent dynamics in the kidney
- moss_kazmierczak_kirley_harris_2009: No JSim version is currently available. (View error log)
muller_obeyesekere_mills_ram_2008
Network topology determines dynamics of the mammalian MAPK1,2 signaling network: bifan motif regulation of C-Raf and B-Raf isoforms by FGFR and MC1R
- muller_obeyesekere_mills_ram_2008: View MML (Java required)
nagano_gerritsen_2001
Effects of Neuromuscular Strength Training on Vertical Jumping Performance - A Computer Simulation Study
- nagano_2001: View MML (Java required)
nagerl_novo_mody_vergara_2000
Binding Kinetics of Calbindin-D28k Determined by Flash Photolysis of Caged Ca2+
- nagerl_novo_mody_vergara_2000: View MML
(Java required)
nash_panfilov_2004
Electromechanical model of excitable tissue to study reentrant cardiac arrhythmias
- nash_panfilov_2004: View MML
(Java required)
nazaret_heiske_thurley_mazat_2009
Mitochondrial energetic metabolism: a simplified model of TCA cycle with ATP production (unscaled version)
- nazaret_2009: View MML (Java required)
- nazaret_2009_scaled: View MML
(Java required)
nelson_murray_perelson_2000
A model of HIV-1 pathogenesis that includes an intracellular delay
- nelson_murray_perelson_2000_delay: View MML (Java required)
- nelson_murray_perelson_2000_general: View MML (Java required)
nelson_perelson_1995
Modeling defective interfering virus therapy for AIDS: conditions for DIV survival
- nelson_1995a: View MML (Java required)
- nelson_1995b: View MML (Java required)
neumann_lam_dahari_gretch_wiley_layden_perelson_1998
Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-alpha Therapy
- neumann_lam_dahari_gretch_wiley_layden_perelson_1998: View MML (Java required)
nevo_golding_neumann_schwartz_akselrod_2004
Nevo et al.'s 2004 mathematical model of autoimmunity.
- nevo_golding_neumann_schwartz_akselrod_2004: No JSim version is currently available. (View error log)
niederer_hunter_smith_2006
A quantitative analysis of cardiac myocyte relaxation: a simulation study
- niederer_hunter_smith_2006: View MML (Java required)
niederer_smith_2007
A Mathematical Model of the Slow Force Response to Stretch in Rat Ventricular Myocytes
- niederer_smith_2007: View MML
(Java required)
noble_1962
A Modification of the Hodgkin-Huxley Equations Applicable to Purkinje Fibre Action and Pace-Maker Potentials
- noble_1962: View MML (Java required)
noble_2000
Improved guinea-pig ventricular cell model incorporating a diadic space, IKr and IKs, and length- and tension-dependent processes.
- noble_2000_a: View MML (Java required)
- noble_2000_b: View MML (Java required)
noble_difrancesco_denyer_1989
Ionic Mechanisms in Normal and Abnormal Cardiac Pacemaker Activity
- noble_difrancesco_denyer_1989: View MML (Java required)
noble_noble_1984
A Model of Sino-Atrial Node Electrical Activity Based on a Modification of the DiFrancesco-Noble (1984) Equations
- noble_noble_1984: View MML (Java required)
noble_noble_2001
Remodelling of Calcium Dynamics in Guinea-Pig Ventricular Cells
- noble_noble_2001: View MML (Java required)
noble_noble_bett_earm_ho_so_1991
The Role of Sodium-Calcium Exchange During the Cardiac Action Potential
- noble_noble_bett_earm_ho_so_1991: View MML (Java required)
noble_varghese_kohl_noble_1998
Improved guinea-pig ventricular cell model incorporating a diadic space, IKr and IKs, and length- and tension-dependent processes.
- noble_varghese_kohl_noble_1998_a: View MML (Java required)
- noble_varghese_kohl_noble_1998_b: View MML (Java required)
- noble_varghese_kohl_noble_1998_c: View MML (Java required)
novak_csikasznagy_gyorffy_chen_tyson_1998
Mathematical model of the fission yeast cell cycle with checkpoint controls at the G1/S, G2/M and metaphase/anaphase transitions
- novak_csikasznagy_gyorffy_chen_tyson_1998: View MML (Java required)
novak_pataki_ciliberto_tyson_2001
Mathematical model of the cell division cycle of fission yeast
- novak_pataki_ciliberto_tyson_2001: View MML (Java required)
novak_tyson_1993
Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos.
- novak_tyson_1993_a: View MML (Java required)
- novak_tyson_1993_b: View MML (Java required)
novak_tyson_1997
Modeling the control of DNA replication in fission yeast
- novak_tyson_1997: View MML (Java required)
novak_tyson_2004
A model for restriction point control of the mammalian cell cycle
- novak_tyson_2004: View MML (Java required)
nowak_bangham_1996
Population dynamics of immune responses to persistent viruses
- nowak_bangham_1996: View MML (Java required)
- nowak_bangham_1996b: View MML (Java required)
nygren_fiset_firek_clark_lindblad_clark_giles_1998
Mathematical Model of an Adult Human Atrial Cell: The Role of K+ Currents in Repolarization
- nygren_fiset_firek_clark_lindblad_clark_giles_1998: View MML (Java required)
obeyesekere_zimmerman_tecarro_auchmuty_1999
A model of cell cycle behavior dominated by kinetics of a pathway stimulated by growth factors
- obeyesekere_zimmerman_tecarro_auchmuty_1999: View MML (Java required)
olsen_hauser_kummer_2003
Mechanism of protection of peroxidase activity by oscillatory dynamics
- olsen_hauser_kummer_2003: View MML (Java required)
oomens_maenhout_vanoijen_drost_baaijens_2003
Finite element modelling of contracting skeletal muscle
- oomens_maenhout_vanoijen_drost_baaijens_2003: No JSim version is currently available. (View error log)
ostby_oyehaug_einevoll_nagelhus_plahte_zeuthen_voipio_lloyd_ottersen_omholt_2008
Astrocytic processes explaining neural-activity-induced shrinkage of extraneuronal space
- ostby_oyehaug_einevoll_nagelhus_plahte_zeuthen_voipio_lloyd_ottersen_omholt_2008: No JSim version is currently available. (View error log)
overgaard_2007
PKPD model of interleukin-21 effects on thermoregulation in monkeys--application and evaluation of stochastic differential equations
- overgaard_baseline_2007: View MML (Java required)
- overgaard_pharmacodynamic_2007: View MML (Java required)
oyehaug_ostby_lloyd_omholt_einevoll_2011
Dependence of spontaneous neuronal firing and depolarization block on astroglial membrane processes: Fig 2B
- oyehaug_2009_version1: View MML (Java required)
- oyehaug_2009_version2: View MML (Java required)
oyehaug_ostby_lloyd_ottersen_omholt_einevoll_2009
Dependence of spontaneous neuronal firing and depolarization block on astroglial membrane processes: Fig 2A
- oyehaug_2009_version1: View MML (Java required)
- oyehaug_2009_version2: View MML (Java required)
palecek_horwitz_lauffenburger_1999
Kinetic Model for Integrin-mediated Adhesion Release During Cell Migration
- palecek_horwitz_lauffenburger_1999: No JSim version is currently available. (View error log)
pandit_clark_giles_demir_2001
A Mathematical Model of Action Potential Heterogeneity in Adult Rat Left Ventricular Myocytes
- pandit_clark_giles_demir_2001_endocardial_cell: View MML (Java required)
- pandit_clark_giles_demir_2001_epicardial_cell: View MML (Java required)
- pandit_clark_giles_demir_2001_mouse_ventricle: View MML
(Java required)
- pandit_clark_giles_demir_2001_rat_ventricle: View MML
(Java required)
pandit_giles_demir_2003
A Mathematical Model of the Electrophysiological Alterations in Rat Ventricular Myocytes in Type-I Diabetes
- pandit_giles_demir_2003: View MML (Java required)
panerai_1980
A Model of Cardiac Muscle Mechanics and Energetics
- panerai_1980: View MML (Java required)
parent_supplisson_loo_wright_1992
Electrogenic Properties of the Cloned Na+/Glucose Cotransporter: II. A Transport Model under Nonrapid Equilibrium Conditions
- Parent_et_al_1992: View MML (Java required)
- pasek_model_2006: View MML
(Java required)
- pasek_model_2006_surface_membrane: View MML (Java required)
- pasek_model_2006_tubular_membrane: View MML (Java required)
- pasek_simurda_christe_2006_a: View MML (Java required)
- pasek_simurda_christe_2006_b: View MML (Java required)
pasek_simurda_orchard_christe_2008
A model of the guinea-pig ventricular cardiac myocyte incorporating a transverse-axial tubular system
- pasek_simurda_orchard_christe_2008: View MML (Java required)
pedersen_bertram_sherman_2005
Intra- and inter-islet synchronization of metabolically driven insulin secretion
- pedersen_bertram_sherman_2005: View MML (Java required)
perelson_kirschner_deboer_1993
Dynamics of HIV infection of CD4+ T cells
- perelson_1993a: View MML (Java required)
- perelson_1993b: View MML (Java required)
- perelson_1993c: View MML (Java required)
- perelson_1993d: View MML
(Java required)
perelson_neumann_markowitz_leonard_ho_1996
HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time
- perelson_neumann_markowitz_leonard_ho_1996: View MML (Java required)
- peterson_2010: View MML
(Java required)
phillips_2007
A quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system
- phillips_2007: View MML (Java required)
phillips_2008
Sleep deprivation in a quantitative physiologically based model of the ascending arousal system
- phillips_baseline_2008: View MML (Java required)
- phillips_sleep_deprivation_2008: View MML (Java required)
pivonka_zimak_smith_gardiner_dunstan_sims_martin_mundy_2008
Model structure and control of bone remodeling: a theoretical study
- pivonka_2008_matlab: View MML (Java required)
plant_1981
Bifurcation and resonance in a model for bursting nerve cells
- plant_1981: View MML (Java required)
potter_greller_cho_nuttall_stroup_suva_tobin_2005
Response to continuous and pulsatile PTH dosing: a mathematical model for parathyroid hormone receptor kinetics
- potter_greller_cho_nuttall_stroup_suva_tobin_2005_a: View MML (Java required)
- potter_greller_cho_nuttall_stroup_suva_tobin_2005_b: View MML (Java required)
potter_zager_barton_2006
Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats.
- potter_zager_barton_2006: View MML (Java required)
priebe_beuckelmann_1998
Simulation Study of Cellular Electrical Properties in Heart Failure
- priebe_beuckelmann_1998: View MML (Java required)
proctor_2005
Modelling the actions of chaperones and their role in ageing.
- proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005: View MML (Java required)
proctor_2007
An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline
- proctor_tsirigotis_gray_2007: View MML (Java required)
puglisi_bers_2001
LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport
- puglisi_bers_2001: View MML
(Java required)
purvis_butera_2005
Ionic Current Model of a Hypoglossal Motoneuron
- purvis_butera_2005: View MML (Java required)
purvis_smith_koizumi_butera_2007
Intrinsic Bursters Increase the Robustness of Rythm Generation in an Excitatory Network
- purvis_smith_koizumi_butera_2007: View MML (Java required)
- purvis_smith_koizumi_butera_2007_npc: View MML (Java required)
qu_maclellan_weiss_2003
Dynamics of the Cell Cycle: Checkpoints, Sizers, and Timers
- qu_maclellan_weiss_2003: View MML (Java required)
ralser_wamelink_kowald_gerisch_heeren_struys_klipp_jakobs_breitenbach_lehrach_krobitsch_2007
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress
- ralser_2007: View MML (Java required)
ramirez_nattel_courtemanche_2000
Mathematical analysis of canine atrial action potentials: rate, regional factors, and electrical remodeling
- ramirez_nattel_courtemanche_2000: View MML
(Java required)
rangamani_2007
Survival and apoptotic pathways initiated by TNF-alpha: modeling and predictions
- rangamani_2007: View MML (Java required)
raposo_sobrinho_ferreira_2002
A minimal mathematical model of calcium homeostasis
- raposo_2002: View MML (Java required)
rattananakul_lenbury_krishnamara_wollkind_2003
Modeling of bone formation and resorption mediated by parathyroid hormone: response to estrogen/PTH therapy
- rattananakul_lenbury_krishnamara_wollkind_2003_a: View MML (Java required)
- rattananakul_lenbury_krishnamara_wollkind_2003_b: View MML (Java required)
- rattananakul_lenbury_krishnamara_wollkind_2003_c: View MML (Java required)
razumova_bukatina_campbell_1999
Stiffness-distortion sacromere model for muscle stimulation
- razumova_bukatina_campbell_1999: View MML (Java required)
razumova_bukatina_campbell_2000
Different Myofilament Nearest-Neighbor Interactions Have Distinctive Effects on Contractile Behavior
- razumova_bukatina_campbell_2000: View MML (Java required)
reed_nijhout_sparks_ulrich_2004
A mathematical model of the methionine cycle
- reed_nijhout_sparks_ulrich_2004: View MML (Java required)
reidl_borowski_sensse_starke_zapotocky_eiswirth_2006
Model of Calcium Oscillations Due to Negative Feedback in Olfactory Cilia
- reidl_borowski_sensse_starke_zapotocky_eiswirth_2006: View MML
(Java required)
revilla_garcia-ramos_2003
Fighting a virus with a virus: a dynamic model for HIV-1 therapy
- revilla_garcia-ramos_2003: View MML (Java required)
riccobene_omann_linderman_1999
Modeling Activation and Desensitisation of G-Protein Coupled Receptors Provides Insight into Ligand Efficacy
- riccobene_omann_linderman_1999: View MML (Java required)
rice_jafri_winslow_2000
Modeling short-term interval-force relations in cardiac muscle
- rice_jafri_winslow_2000: View MML
(Java required)
rice_wang_bers_detombe_2008
Approximate model of cooperative activation and crossbridge cycling in cardiac muscle using ordinary differential equations
- rice_wang_bers_detombe_2008: View MML (Java required)
rice_winslow_hunter_1999
Comparison of putative cooperative mechanisms in cardiac muscle: length dependence and dynamic responses (model 1)
- rice_winslow_hunter_1999_a: View MML (Java required)
- rice_winslow_hunter_1999_b: View MML
(Java required)
- rice_winslow_hunter_1999_c: View MML
(Java required)
- rice_winslow_hunter_1999_d: View MML
(Java required)
- rice_winslow_hunter_1999_e: View MML
(Java required)
rice_winslow_jafri_1999
Modeling Gain and Gradedness of Ca2+ Release in the Functional Unit of the Cardiac Diadic Space
- rice_winslow_jafri_1999: No JSim version is currently available. (View error log)
riemer_sobie_tung_1998
Stretch-induced changes in arrhythmogenesis and excitability in experimentally based heart cell models
- riemer_sobie_tung_1998: View MML
(Java required)
rivlin_saunders_1951
Large Elastic Deformations of Isotropic Materials. VII. Experiments on the Deformation of Rubber
- rivlin_saunders_1951: View MML (Java required)
rogers_mcculloch_1994
A collocation--Galerkin finite element model of cardiac action potential propagation
- rogers_mcculloch_1994: View MML (Java required)
romond_rustici_gonze_goldbeter_1999
Alternating Oscillations and Chaos in a Model of Two Coupled Biochemical Oscillators Driving Successive Phases of the Cell Cycle
- romond_rustici_gonze_goldbeter_1999: View MML (Java required)
rong_perelson_2009
Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy
- rong_2009a: View MML (Java required)
- rong_2009b: View MML (Java required)
roux_noble_noble_marhl_2006
Modelling of calcium handling in airway myocytes
- roux_noble_noble_marhl_2006: View MML (Java required)
rubin_shevtsova_ermentrout_smith_rybak_2009
Multiple rhythmic states in a model of the respiratory central pattern generator
- rubin_2009: View MML (Java required)
sachse_glanzel_seemann_2003
Modeling of Protein Interactions Involved in Cardiac Tension Development
- sachse_glanzel_seemann_2003: No JSim version is currently available. (View error log)
sachse_moreno_abildskov_2008
Electrophysiological Modeling of Fibroblasts and Their Interaction with Myocytes
- sachse_moreno_abildskov_2008_a: View MML (Java required)
- sachse_moreno_abildskov_2008_b: View MML (Java required)
saftenku_williams_sitsapesan_2001
Markovian Models of Low and High Activity Levals of Cardiac Ryanodine Receptors
- saftenku_williams_sitsapesan_2001_H1_model: View MML (Java required)
- saftenku_williams_sitsapesan_2001_H2_model: View MML (Java required)
- saftenku_williams_sitsapesan_2001_low_model: View MML (Java required)
sakmann_spindler_bryant_linz_noble_2000
Distribution of a persistent sodium current across the ventricular wall in guinea pigs.
- sakmann_spindler_bryant_linz_noble_2000_a: View MML (Java required)
- sakmann_spindler_bryant_linz_noble_2000_b: View MML (Java required)
- sakmann_spindler_bryant_linz_noble_2000_c: View MML (Java required)
salem_saidel_stanley_cabrera_2002
Mechanistic Model of Myocardial Energy Metabolism Under Normal and Ischemic Conditions
- salem_saidel_stanley_cabrera_2002: View MML (Java required)
sarai_matsuoka_kuratomi_ono_noma_2003
Role of individual ionic current systems in the SA node hypothesized by a model study
- sarai_matsuoka_kuratomi_ono_noma_2003: View MML (Java required)
sarkar_lauffenburger_2003
Cell-Level Pharmacokinetic Model of Granulocyte Colony-Stimulating Factor: Implications for Ligand Lifetime and Potency in Vivo
- sarkar_lauffenburger_2003: View MML
(Java required)
- saucerman_2008_cytosol: View MML (Java required)
- saucerman_2008_dyadic_cleft: View MML (Java required)
- saucerman_2008_sarcolemma: View MML (Java required)
- saucerman_bers_2008: View MML (Java required)
saucerman_brunton_michailova_mcculloch_2003
Modeling beta-adrenergic control of cardiac myocyte contractility in silico
- saucerman_brunton_michailova_mcculloch_2003: No JSim version is currently available. (View error log)
saucerman_mcculloch_2004
Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation
- saucerman_mcculloch_2004: View MML (Java required)
schenzle_1994
A model for AIDS pathogenesis
- schenzle_1994: View MML (Java required)
schlosser_selgrade_2000
A model of gonadotropin regulation during the menstrual cycle in women: qualitative features
- schlosser_selgrade_2000: View MML (Java required)
schmid_nash_young_hunter_2006
Myocardial Material Parameter Estimation - A Comparative Study for Simple Shear
- schmid_nash_young_hunter_2006_a: View MML (Java required)
- schmid_nash_young_hunter_2006_b: View MML (Java required)
schneider_shimayoshi_amano_matsuda_2006
Mechanism of the Frank-Starling law-- A simulation study with a novel cardiac muscle contraction model that includes titin and tropomyosin
- schneider_shimayoshi_amano_matsuda_2006: View MML (Java required)
schoeberl_eichlerjonsson_gilles_muller_2002
Computational Modeling of the Dynamics of the MAP Kinase Cascade Activated by Surface and Internalized EGF Receptors.
- Schoeberl_EichlerJonsson_Gilles_Muller_2002: View MML (Java required)
schuster_beny_meister_2003
Modelling the electrophysiological endothelial cell response to bradykinin
- schuster_beny_meister_2003: View MML
(Java required)
sedaghat_sherman_quon_2002
A mathematical model of metabolic insulin signaling pathways
- sedaghat_sherman_quon_2002: View MML
(Java required)
- sedaghat_sherman_quon_2002_feedback: View MML
(Java required)
seemann_sachse_weib_dossel_2003
Quantitative Reconstruction of Cardiac Electromechanics in Human Myocardium: Regional Heterogeneity
- seemann_sachse_weib_dossel_2003: No JSim version is currently available. (View error log)
shannon_wang_puglisi_weber_bers_2004
A Mathematical Treatment of Integrated Ca Dynamics within the Ventricular Myocyte
- shannon_wang_puglisi_weber_bers_2004_a: View MML (Java required)
- shannon_wang_puglisi_weber_bers_2004_b: View MML (Java required)
shaw_chase_starfinger_smith_hann_desaive_ghuysen_2007
Modeling the Cardiovascular System
- shaw_chase_starfinger_smith_hann_desaive_ghuysen_2007: View MML
(Java required)
shaw_rudy_1997
Electrophysiological effects of acute myocardial ischemia: a theoretical study of altered cell excitability and action potential duration
- shaw_rudy_1997: View MML
(Java required)
- EAtrium: No JSim version is currently available. (View error log)
- EVentricle: No JSim version is currently available. (View error log)
- ModelHeart: No JSim version is currently available. (View error log)
- ModelMain: No JSim version is currently available. (View error log)
- ModelPul: No JSim version is currently available. (View error log)
- ModelSys: No JSim version is currently available. (View error log)
- ParaHeart: View MML (Java required)
- ParaPul: View MML (Java required)
- ParaSys: View MML (Java required)
- TempCDa: No JSim version is currently available. (View error log)
- TempCDv: No JSim version is currently available. (View error log)
- TempR: No JSim version is currently available. (View error log)
- TempRC: No JSim version is currently available. (View error log)
- TempRLC: No JSim version is currently available. (View error log)
- TestCDv3: No JSim version is currently available. (View error log)
- Units: View MML (Java required)
shiferaw_watanabe_garfinkel_weiss_karma_2003
Model of Intracellular Calcium Cycling in Ventricular Myocytes
- shiferaw_watanabe_garfinkel_weiss_karma_2003: View MML
(Java required)
- shim_leem_abe_noma_2006: View MML (Java required)
shorten_ocallaghan_davidson_soboleva_2007
A mathematical model of fatigue in skeletal muscle force contraction
- shorten_ocallaghan_davidson_soboleva_2007: View MML (Java required)
- shorten_ocallaghan_davidson_soboleva_2007_variant01: View MML (Java required)
shorten_robson_mckinnon_wall_2000
CRH-induced Electrical Activity and Calcium Signalling in Pituitary Corticotrophs
- shorten_robson_mckinnon_wall_2000: View MML
(Java required)
shorten_wall_2000
A Hodgkin-Huxley Model Exhibiting Bursting Oscillations
- shorten_wall_2000: View MML (Java required)
shrestha_hollot_chipkin_schmitt_chait_2010
A mathematical model of parathyroid hormone response to acute changes in plasma ionized calcium concentration in humans
- shrestha_2010: View MML (Java required)
siebert_rode_herzog_till_blickhan_2008
Nonlinearities make a difference: comparison of two common Hill-type models with real muscle
- siebert_CC_2008: View MML (Java required)
- siebert_CC_SEC_2008: View MML (Java required)
skouibine_trayanova_moore_1999
Anode/cathode make and break phenomena in a model of defibrillation
- skouibine_trayanova_moore_1999: View MML
(Java required)
smith_1980
Hypothalamic regulation of pituitary secretion of luteinizing hormone. II. Feedback control of gonadotropin secretion
- smith_1980: View MML (Java required)
smith_abdala_koizumi_rybak_paton_2007
- smith_2007_aug_E: View MML (Java required)
- smith_2007_early_I: View MML (Java required)
- smith_2007_post_I: View MML (Java required)
- smith_2007_pre_I: View MML (Java required)
- smith_2007_synaptic_coupling: No JSim version is currently available. (View error log)
smith_chase_nokes_shaw_wake_2004
Minimal haemodynamic system model including ventricular interaction and valve dynamics.
- smith_chase_nokes_shaw_wake_2004: View MML (Java required)
smith_crampin_2004
Development of models of active ion transport for whole-cell modelling: cardiac sodium-potassium pump as a case study
- smith_crampin_2004: View MML (Java required)
sneyd_dufour_2002
A dynamic model of the type-2 inositol triphosphate receptor
- sneyd_dufour_2002: View MML (Java required)
sneyd_tsaneva-atanasova_yule_thompson_shuttleworth_2004
Sneyd et al.'s 2004 mathematical model for Ca2+ oscillations and their control by membrane fluxes.
- sneyd_tsaneva-atanasova_yule_thompson_shuttleworth_2004: View MML (Java required)
sneyd_tsanevaatanasova_bruce_straub_giovannucci_yule_2003
A Model of Calcium Waves in Pancreatic and Parotid Acinar Cells
- sneyd_tsanevaatanasova_bruce_straub_giovannucci_yule_2003: No JSim version is currently available. (View error log)
sneyd_wetton_charles_sanderson_1995
Intercellular calcium waves mediated by diffusion of inositol trisphosphate: a two-dimensional model
- sneyd_1995: View MML (Java required)
snyder_palmer_moore_2000
A Mathematical Model of Cardiocyte Ca2+ Dynamics with a Novel Representation of Sarcoplasmic Reticular Ca2+ Control
- snyder_palmer_moore_2000: View MML (Java required)
sobie_dilly_dossantoscruz_lederer_jafri_2002
Termination of Cardiac Ca2+ Sparks: An Investigative Mathematical Model of Calcium-Induced Calcium Release
- sobie_dilly_dossantoscruz_lederer_jafri_2002: No JSim version is currently available. (View error log)
soboleva_vetharaniam_nixon_montenegro_pearson_sneyd_2005
Mathematical modelling of prolactin-receptor interaction and the corollary for prolactin receptor gene expression in skin
- soboleva_vetharaniam_nixon_montenegro_pearson_sneyd_2005_a: View MML (Java required)
- soboleva_vetharaniam_nixon_montenegro_pearson_sneyd_2005_b: View MML
(Java required)
spiro_parkinson_othmer_1997
A model of excitation and adaptation in bacterial chemotaxis
- spiro_parkinson_othmer_1997: View MML (Java required)
sriram_bernot_kepes_2007
A minimal mathematical model combining several regulatory cycles from the budding yeast cell cycle
- sriram_bernot_kepes_2007: View MML (Java required)
starbuck_wiley_lauffenburger_1990
Epidermal Growth Factor Binding and Trafficking Dynamics in Fibroblasts: Relationship to Cell Proliferation
- starbuck_wiley_lauffenburger_1990: View MML
(Java required)
stern_song_sham_yang_boheler_rios_1999
Local Control Models of Cardiac Excitation-Contraction Coupling A Possible Role for Allosteric Interactions between Ryanodine Receptors
- stern_song_sham_yang_boheler_rios_1999: View MML (Java required)
stewart_aslanidi_noble_noble_boyett_zhang_2009
Mathematical models of the electrical action potential of Purkinje fibre cells
- stewart_aslanidi_noble_noble_boyett_zhang_2009: View MML (Java required)
sthilaire_gronfier_zeitzer_klerman_2007
A physiologically based mathematical model of melatonin including ocular light suppression and interactions with the circadian pacemaker
- sthilaire_gronfier_zeitzer_klerman_2007: View MML
(Java required)
stilianakis_dietz_schenzle_1997
Analysis of a Model for the Pathogenesis of AIDS
- stilianakis_dietz_schenzle_1997: View MML (Java required)
surkis_peskin_tranchina_leonard_1998
Recovery of Cable Properties Through Active and Passive Modeling of Subthreshold Membrane Responses From Laterodorsal Tegmental Neurons
- surkis_peskin_tranchina_leonard_1998: No JSim version is currently available. (View error log)
sveiczer_csikasznagy_gyorffy_tyson_novak_2000
Modeling the fission yeast cell cycle: quantized cycle times in wee1- cdc25Delta mutant cells.
- sveiczer_csikasznagy_gyorffy_tyson_novak_2000: View MML (Java required)
swanson_true_lin_buhler_vessella_murray_2001
A Quantitative Model for the Dynamics of Serum Prostate-Specific Antigen as a Marker for Cancerous Growth
- swanson_true_lin_buhler_vessella_murray_2001: View MML (Java required)
- swat_2004: View MML (Java required)
tabak_mascagni_bertram_2010
Mechanism for the Universal Pattern of Activity in Developing Neuronal Networks
- tabak_mascagni_bertram_2010: View MML (Java required)
tabak_toporikova_freeman_bertram_2007
Low dose of dopamine may stimulate prolactin secretion by increasing fast potassium currents
- tabak_toporikova_freeman_bertram_2007_a: View MML (Java required)
- tabak_toporikova_freeman_bertram_2007_b: View MML (Java required)
tentusscher_noble_noble_panfilov_2004
A model for human ventricular tissue
- tentusscher_noble_noble_panfilov_2004_a: View MML (Java required)
- tentusscher_noble_noble_panfilov_2004_b: View MML (Java required)
- tentusscher_noble_noble_panfilov_2004_c: View MML (Java required)
tentusscher_noble_noble_panfilov_2006
- tentusscher_noble_noble_panfilov_2006_c: View MML
(Java required)
tentusscher_panfilov_2006
Alternans and spiral breakup in a human ventricular tissue model.
- ten_tusscher_model_2006_IK1Ko_M_units: View MML (Java required)
- ten_tusscher_model_2006_IK1Ko_endo_units: View MML (Java required)
- ten_tusscher_model_2006_IK1Ko_epi_units: View MML (Java required)
terkildsen_niederer_crampin_hunter_smith_2008
- Hinch_et_al_2004: View MML (Java required)
- Niederer_et_al_2006: View MML (Java required)
- Pandit_Hinch_Niederer: View MML (Java required)
- Pandit_et_al_2001_endo: View MML (Java required)
- terkildsen_niederer_crampin_hunter_smith_2008: View MML (Java required)
teusink_passarge_reijenga_esgalhado_vanderweijden_schepper_walsh_bakker_vandam_westerhoff_snoep_2000
Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry.
- teusink_annotated_2000: View MML (Java required)
- teusink_passarge_reijenga_esgalhado_vanderweijden_schepper_walsh_bakker_vandam_westerhoff_snoep_2000: View MML (Java required)
tham_2008
A pharmacodynamic model for the time course of tumor shrinkage by gemcitabine + carboplatin in non-small cell lung cancer patients
- tham_2008: View MML (Java required)
thomas_2000
Inner medullary lactate production and accumulation: a vasa recta model
- thomas_2000: View MML (Java required)
thomsen_neubig_1989
Rapid kinetics of alpha 2-adrenergic inhibition of adenylate cyclase. Evidence for a distal rate-limiting step
- thomsen_neubig_1989: View MML
(Java required)
tolic_mosekilde_sturis_2000
Modelling the Insulin-Glucose Feedback System: The Significance of Pulsatile Insulin Secretion
- tolic_mosekilde_sturis_2000: View MML (Java required)
tomida_hirose_takizawa_shibasaki_iino_2003
NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation
- tomida_hirose_takizawa_shibasaki_iino_2003: View MML (Java required)
topp_promislow_devries_miura_finegood_2000
A Model of Beta-Cell Mass, Insulin, and Glucose Kinetics: Paythways to Diabetes
- topp_promislow_devries_miura_finegood_2000: View MML (Java required)
tran_2009
A metabolite-sensitive, thermodynamically-constrained model of cardiac cross-bridge cycling: Implications for force development during ischemia
- tran_2009: View MML (Java required)
tran_smith_loiselle_crampin_2009
A Thermodynamic Model of the Cardiac Sarcoplasmic/Endoplasmic Ca(2+) (SERCA) Pump
- tran_smith_loiselle_crampin_2009: View MML (Java required)
- tran_smith_loiselle_crampin_2009_variant01: View MML (Java required)
tyson_1991
Modeling the Cell Division Cycle:cdc2 and Cyclin Interactions
- tyson_1991: View MML (Java required)
tyson_hong_thron_novak_1999
A Simple Model of Circadian Rhythms Based on Dimerization and Proteolysis of PER and TIM
- tyson_hong_thron_novak_1999: View MML (Java required)
ueda_hagiwara_kitano_2001
Robust oscillations within the interlocked feedback model of Drosophila circadian rhythm
- ueda_hagiwara_kitano_2001: View MML (Java required)
vanbeek_2007
Adenine nucleotide-creatine-phosphate module in myocardial metabolic system explains fast phase of dynamic regulation of oxidative phosphorylation
- vanbeek_2007: View MML (Java required)
vancapelle_durrer_1980
Computer simulation of arrhythmias in a network of coupled excitable elements
- vancapelle_durrer_1980: View MML
(Java required)
vanderpol_vandermark_1928
The Heartbeat Considered as a Relaxation Oscillation, and an Electrical Model of the Heart.
- vanderpol_vandermark_1928: View MML (Java required)
vangoor_lebeau_krsmanovic_sherman_catt_stojilkovic_2000
Amplitude-Dependent Spike-Broadening and Enhanced Ca2+ Signaling in GnRH-Secreting Neurons
- vangoor_lebeau_krsmanovic_sherman_catt_stojilkovic_2000: No JSim version is currently available. (View error log)
vasalou_henson_2010
A multiscale model to investigate circadian rhythmicity of pacemaker neurons in the suprachiasmatic nucleus
- vasalou_2010: View MML (Java required)
vaseghi_baumeister_rizzi_reuss_1999
In Vivo Dynamics of the Pentose Phosphate Pathway in Saccharomyces cerevisiae
- vaseghi_baumeister_rizzi_reuss_1999: View MML (Java required)
vempati_karagiannis_popel_2007
A Biochemical Model of Matrix Metalloproteinase 9 Activation and Inhibition
- vempati_karagiannis_popel_2007: View MML (Java required)
vendelin_kongas_saks_2000
Regulation of mitochondrial respiration in heart cells analyzed by reaction-diffusion model of energy transfer
- vendelin_kongas_saks_2000: No JSim version is currently available. (View error log)
vilar_2006
Signal processing in the TGF-beta superfamily ligand-receptor network
- vilar_2006: View MML (Java required)
- vilar_rnx_2006: View MML (Java required)
vilar_kueh_barkai_leibler_2002
Mechanisms of noise-resistance in genetic oscillators
- vilar_kueh_barkai_leibler_2002: View MML (Java required)
vinnakota_kemp_kushmerick_2006
Dynamics of Muscle Glycogenolysis Modeled with pH Time Course Computation and pH-Dependent Reaction Equilibria and Enzyme Kinetics
- vinnakota_kemp_kushmeric_2006_exp29frA02: View MML (Java required)
- vinnakota_kemp_kushmeric_2006_exp29frA40: View MML (Java required)
- vinnakota_kemp_kushmeric_2006_exp45: View MML (Java required)
vinnakota_rusk_palmer_shankland_kushmerick_2010
Common Phenotype of Resting Mouse EDL and SOL Muscles: EDL
- vinnakota_rusk_palmer_shankland_kushmeric_2010_edl: View MML (Java required)
- vinnakota_rusk_palmer_shankland_kushmeric_2010_soleus: View MML (Java required)
viswanathan_shaw_rudy_1999
Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study (Midmyocardial Cell Model)
- viswanathan_shaw_rudy_1999_a: View MML (Java required)
- viswanathan_shaw_rudy_1999_b: View MML (Java required)
- viswanathan_shaw_rudy_1999_c: View MML (Java required)
wanant_quon_2000
Insulin receptor binding kinetics: modeling and simulation studies
- wanant_quon_2000_a: View MML (Java required)
- wanant_quon_2000_b: View MML (Java required)
wang_cirit_haugh_2009
PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk
- wang_2009: View MML (Java required)
wang_huang_huang_2006
A quantitative kinetic model for ATP-induced intracellular Ca2+ oscillations
- wang_2006: View MML (Java required)
wang_li_kuang_2007
Mathematical modeling and qualitative analysis of insulin therapies
- wang_li_kuang_2007: View MML (Java required)
wang_lin_lin_wu_2008
Effect of riluzole on action potential in cultured human skeletal muscle cells
- wang_lin_lin_wu_2008: View MML (Java required)
wang_sobie_2008
Mathematical model of the neonatal mouse ventricular action potential
- wang_sobie_2008: View MML (Java required)
warashina_ogura_2004
Modeling of simulation-secretion coupling in a chromaffin cell
- warashina_ogura_2004: View MML
(Java required)
warren_tawhai_crampin_2009
Mathematical modelling of calcium wave propagation in mammalian airway epithelium: evidence for regenerative ATP release
- warren_2010: View MML (Java required)
waugh_sherratt_2006
Macrophage Dynamics in Diabetic Wound Healing
- waugh_sherratt_2006_a: View MML (Java required)
- waugh_sherratt_2006_b: View MML
(Java required)
- waugh_sherratt_2006_c: View MML
(Java required)
waugh_sherratt_2007
Modeling the effects of treating diabetic wounds with engineered skin substitutes
- waugh_sherratt_2007_a: View MML
(Java required)
- waugh_sherratt_2007_b: View MML
(Java required)
- waugh_sherratt_2007_c: View MML
(Java required)
- waugh_sherratt_2007_d: View MML
(Java required)
webb_sherratt_fish_2002
Cells behaving badly: a theoretical model for the Fas/FasL system in tumour immunology
- webb_sherratt_fish_2002: View MML (Java required)
wein_damato_perelson_1998
Mathematical analysis of antiretroviral therapy aimed at HIV-1 eradication or maintenance of low viral loads
- wein_1998: View MML (Java required)
- Weinstein_1995_NHE3: View MML (Java required)
- Weinstein_1995_NHE3_Fig2: View MML (Java required)
- Weinstein_1995_NHE3_Fig3: View MML (Java required)
- Weinstein_1995_NHE3_Fig3b: View MML (Java required)
- Weinstein_1995_NHE3_Fig4: View MML (Java required)
- Weinstein_1995_NHE3_Fig4b: View MML (Java required)
- Weinstein_1995_NHE3_Fig5: View MML (Java required)
weinstein_1998
A mathematical model of the inner medullary collecting duct of the rat: acid/base transport
- weinstein_1998_variant01: View MML (Java required)
- weinstein_1998_variant02: View MML
(Java required)
weinstein_2000
A mathematical model of the outer medullary collecting duct of the rat
- Weinstein_2000_AE1: View MML (Java required)
- cons_law1: View MML (Java required)
- cons_law2: View MML (Java required)
- cons_law3: View MML (Java required)
- westermark_2003_1.1: View MML
(Java required)
- westermark_lansner_2003: View MML
(Java required)
wierschem_bertram_2004
Complex bursting in pancreatic islets: a potential glycolytic mechanism
- wierschem_2004: View MML (Java required)
wilkins_sneyd_1998
Intercellular Spiral Waves of Calcium
- wilkins_sneyd_1998: No JSim version is currently available. (View error log)
winograd_destexhe_sanchezvives_2008
Hyperpolarization-activated graded persistent activity in the prefrontal cortex
- winograd_destexhe_sanchezvives_2008: View MML (Java required)
winslow_rice_jafri_marban_ororke_1999
Mechanisms of Altered Excitation-Contraction Coupling in Canine Tachycardia-Induced Heart Failure, II Model Studies
- winslow_rice_jafri_marban_ororke_1999: View MML (Java required)
wodarz_2003
Evolution of Immunological Memory and the Regulation of Competition between Pathogens
- wodarz_2003: View MML (Java required)
wodarz_hamer_2007
Infection dynamics in HIV-specific CD4 T cells: Does a CD4 T cell boost benefit the host or the virus?
- wodarz_hamer_2007_a: View MML (Java required)
- wodarz_hamer_2007_b: View MML (Java required)
- wodarz_hamer_2007_c: View MML (Java required)
- wodarz_hamer_2007_d: View MML (Java required)
wodarz_jansen_2003
A dynamical perspective of CTL cross-priming and regulation: implications for cancer immunology
- wodarz_jansen_2003: View MML (Java required)
wodarz_nowak_1999
Specific therapy regimes could lead to long-term immunological control of HIV
- wodarz_nowak_1999: View MML (Java required)
wodarz_sierro_klenerman_2007
Dynamics of killer T cell inflation in viral infections
- wodarz_sierro_klenerman_2007_a: View MML (Java required)
- wodarz_sierro_klenerman_2007_b: View MML (Java required)
- wodarz_sierro_klenerman_2007_c: View MML (Java required)
wolf_heinrich_2000
Effect of cellular interaction on glycolytic oscillations in yeast: a theoretical investigation
- wolf_heinrich_2000: View MML (Java required)
wolf_passarge_somsen_snoep_heinrich_westerhoff_2000
Transduction of Intracellular and Intercellular Dynamics in Yeast Glycolytic Oscillations
- wolf_passarge_somsen_snoep_heinrich_westerhoff_2000: View MML (Java required)
wolf_sohn_heinrich_kuriyama_2001
Mathematical analysis of a mechanism for autonomous metabolic oscillations in continuous culture of Saccharomyces cerevisae
- wolf_sohn_heinrich_kuriyama_2001: View MML (Java required)
wu_jeneson_beard_2006
Oxidative ATP Synthesis in Skeletal Muscle is Controlled by Substrate Feedback
- wu_jeneson_beard_2006: View MML (Java required)
wu_yang_vinnakota_beard_2007
Computer Modeling of Mitochondrial Tricarboxylic Acid Cycle, Oxidative Phosphorylation, Metabolite Transport, and Electrophysiology
- wu_yang_vinnakota_beard_2007: View MML (Java required)
yamaguchi_takaki_matsubara_yasuhara_suga_1996
Constancy and variability of contractile efficiency as a function of calcium and cross-bridge kinetics: simulation
- yamaguchi_takaki_matsubara_yasuhara_suga_1996: View MML (Java required)
yanagihara_1980
Reconstruction of sino-atrial node pacemaker potential based on the voltage clamp experiments
- yanagihara_model_1980: View MML (Java required)
yang_clark_bryan_robertson_2003
The myogenic response in isolated rat cerebrovascular arteries: smooth muscle cell model
- yang_clark_bryan_robertson_2003: View MML
(Java required)
yang_tong_mccarver_hines_beard_2006
Population-Based Analysis of Methadone Distribution and Metabolism Using an Age-Dependent Physiologically Based Pharmacokinetic Model
- yang_tong_mccarver_hines_beard_2006: View MML (Java required)
yasamura_suga_1987
Crossbridge Model Compatible with the Linear Relationship between Left Ventricular Oxygen Consumption and Pressure-Volume Area
- yasumura_1988: No JSim version is currently available. (View error log)
yates_stark_klein_antia_callard_2007
Understanding the slow depletion of memory CD4+ T cells in HIV infection
- yates_stark_klein_antia_callard_2007_a: View MML (Java required)
- yates_stark_klein_antia_callard_2007_b: View MML (Java required)
- yates_stark_klein_antia_callard_2007_c: View MML (Java required)
yi_fogelson_keener_peskin_2003
A Mathematical Study of Volume Shifts and Ionic Concentration Changes during Ischemia and Hypoxia
- yi_fogelson_keener_peskin_2003: View MML
(Java required)
youm_kim_han_kim_joo_leem_goto_noma_earm_2006
A mathematical model of pacemaker activity recorded from mouse small intestine
- youm_kim_han_kim_joo_leem_goto_noma_earm_2006: View MML (Java required)
zager_schlosser_tran_2007
A delayed nonlinear PBPK model for genistein dosimetry in rats
- zager_schlosser_tran_2007: View MML (Java required)
zeng_laurita_rosenbaum_rudy_1995
Two Components of the Delayed Rectifier K+ Current in Ventricular Myocytes of the Guinea Pig Type
- zeng_laurita_rosenbaum_rudy_1995: View MML
(Java required)
zhang_holden_kodama_honjo_lei_varghese_boyett_2000
Mathematical models of action potentials in the periphery and center of the rabbit sinoatrial node.
- zhang_holden_kodama_honjo_lei_varghese_boyett_2000: View MML (Java required)
Model development and archiving support at physiome.org provided by the following grants: NIH U01HL122199 Analyzing the Cardiac Power Grid, 09/15/2015 - 05/31/2020, NIH/NIBIB BE08407 Software Integration, JSim and SBW 6/1/09-5/31/13; NIH/NHLBI T15 HL88516-01 Modeling for Heart, Lung and Blood: From Cell to Organ, 4/1/07-3/31/11; NSF BES-0506477 Adaptive Multi-Scale Model Simulation, 8/15/05-7/31/08; NIH/NHLBI R01 HL073598 Core 3: 3D Imaging and Computer Modeling of the Respiratory Tract, 9/1/04-8/31/09; as well as prior support from NIH/NCRR P41 RR01243 Simulation Resource in Circulatory Mass Transport and Exchange, 12/1/1980-11/30/01 and NIH/NIBIB R01 EB001973 JSim: A Simulation Analysis Platform, 3/1/02-2/28/07.