A model of pulmonary circulation based on Olansen et al. (2000) and Lu et al. (2001). A model of pulmonary circulation in which a right ventricle input pressure pulse drives blood flow through vascular components.
Model number: 0181
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This is a model of pulmonary circulation based on Olansen et al. (2000) and Lu et al. (2001). A right ventricle input pressure pulse drives blood flow through the following vascular components: proximal pulmonary artery, distal pulmonary artery, pulmonary arterioles, pumonary capillaries and pulmonary veins. All of these compartments are modeled as windkessels, with single resistance and compliance parameters. The proximal and distal pulmonary artery segments are also characterized with inertance parameters. Parameter values for distal pulmonary inertance and radial flow resistance were not provided in Lu et al. (2001)
Figure: Schematic representation of Pulmonary circulation model.
The equations for this model may be viewed by running the JSim model applet and clicking on the Source tab at the bottom left of JSim's Run Time graphical user interface. The equations are written in JSim's Mathematical Modeling Language (MML). See the Introduction to MML and the MML Reference Manual. Additional documentation for MML can be found by using the search option at the Physiome home page.
Lu K, Clark JW, Ghorbel FH, Ware DL, Bidani A. A human cardiopulmonary system model applied to the analysis of the Valsalva maneuver. Am J Physiol Heart Circ Physiol. 281: H2661-H2679, 2001. Olansen JB, Clark JW, Khoury D, Ghorbel F, Bidani A. A closed-loop model of the canine cardiovascular system that includes ventricular interaction. Computers and Biomedical Research. 33: 260-295, 2000. Ohm GS. Die galvanische Kette mathematisch bearbeitet, 1827
- Resistive Element (Model #0069)
- Compliant Element (#0067)
- Single Vessel (#0218)
- Systemic Circulation Olansen et al. 2000 (#0224)
- Pulmonary Circulation Olansen et al. 2000 (#0181)
- Coronary Circulation Zinemanas et al. 1994 (#0128)
- Baroreceptor Lu et al 2001 (#0075)
- Pressure Driven Single Vessel (#0068)
- Ventricle-driven two vessel loop (#0222)
- Stergiopulos 4-element Windkessel (#0219)
- Lumped parameter circulation (#0160)
- Circulation with baroreceptors (#0095)
- Lumped parameter circulation with regulation (#0161)
- Cardiopulmonary mechanics (#0091)
- Cardiopulmonary mechanics with gas exchange (#0092)
- Cardiopulmonary mechanics with gas exchange and blood gas handling (#0093)
- Highly-integrated human (#0153)
- Highly-integrated human with interventions (#0154)
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[This page was last modified 14Mar18, 3:17 pm.]
Model development and archiving support at physiome.org provided by the following grants: NIH U01HL122199 Analyzing the Cardiac Power Grid, 09/15/2015 - 05/31/2020, NIH/NIBIB BE08407 Software Integration, JSim and SBW 6/1/09-5/31/13; NIH/NHLBI T15 HL88516-01 Modeling for Heart, Lung and Blood: From Cell to Organ, 4/1/07-3/31/11; NSF BES-0506477 Adaptive Multi-Scale Model Simulation, 8/15/05-7/31/08; NIH/NHLBI R01 HL073598 Core 3: 3D Imaging and Computer Modeling of the Respiratory Tract, 9/1/04-8/31/09; as well as prior support from NIH/NCRR P41 RR01243 Simulation Resource in Circulatory Mass Transport and Exchange, 12/1/1980-11/30/01 and NIH/NIBIB R01 EB001973 JSim: A Simulation Analysis Platform, 3/1/02-2/28/07.